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Exendin-4 promotes GSIS without increasing β-cell number through upregulation of glucose-sensing apparatus and mitochondrial oxidative phosphorylation machinery genes in hPSC-deriv...
Published 2023“…Interestingly, addition of Exendin-4 (50 nM) during the last 3 days of the differentiation significantly enhanced GSIS associated with increased expression of glucose-sensing apparatus genes (Glut2, G6P2C, GCK) and genes encoding mitochondrial oxidative phosphorylation machinery.…”
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Deciphering the In vitro Role of microRNAs miR-21-3p and miR-222-5p In the Regulation of Clostridioides difficile Flagellin-Induced Inflammation
Published 2024“…Functional assays revealed that miR-222-5p overexpression led to a significant increased expression of key pro-inflammatory cytokines, including IL-8 and TNF-α, while knockdown of these miRNAs resulted in their decreased expression. …”
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masterThesis -
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The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR)
Published 2023“…These results reiterate the decisive role of 5-Aza-CdR in lung cancer treatment since it induces the epigenetic regulation of NY-ESO-1 antigen, inhibits cell proliferation, increases apoptosis, and decreases invasiveness.…”
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Evapotranspiration and water availability response to climate change in the Middle East and North Africa
Published 2021“…Outcomes reveal that the MENA region is indeed vulnerable to a surge in temperature, which can increase evapotranspiration losses and decrease water availability. …”
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Assessment of High-resolution Local Emissions and Land-use in Air Quality Forecasting at an Urban, Coastal, Desert Environment
Published 2022“…The overall forecast error decreased from –51% to 8% for PM2.5 and from –88% to 20% for NOx while a significant improvement was observed in the diurnal profile of predicted ozone. …”
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Food purchase and eating behavior during the COVID-19 pandemic: A cross-sectional survey of Russian adults
Published 2021“…Indeed, the survey results suggested (i) a change in the modality of acquiring food, consumers reduced the number of shopping trips and buying more on each trip to minimize store visits; (ii) a surge of stockpiling of non-perishable food items; (iii) a shift toward healthier diets; (iv) an increase in culinary capabilities; (v) a decrease of food waste. …”
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SARS‐CoV‐2 infection triggers more potent antibody‐dependent cellular cytotoxicity (ADCC) responses than mRNA‐, vector‐, and inactivated virus‐based COVID‐19 vaccines
Published 2024“…</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Medical Virology<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1002/jmv.29527" target="_blank">https://dx.doi.org/10.1002/jmv.29527</a></p>…”
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The effect of Ramadan focused education on patients with type 2 diabetes: A systematic review and meta-analysis
Published 2020“…</p><h3>Conclusions</h3><p dir="ltr">This systematic review and meta-analysis shows that Ramadan-focused diabetes education leads to a decrease in HbA1c and LDL, but an increase in TG and weight during Ramadan. …”
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Long-Haul Northeast Travel Disrupts Sleep and Induces Perceived Fatigue in Endurance Athletes
Published 2018“…</p><p dir="ltr"><br></p><h3>Results: </h3><p dir="ltr">All comparisons are to baseline. There was a most likely decrease in sleep duration on the over-night flight (-4.8 ± 1.2 h; effect size; ±90% confidence limits = 3.06; ±1.26) and a very likely increase in sleep duration on the first night after arrival (0.7 ± 1.0 h; 1.15; ±0.92). …”
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Crystallization properties of arsenic doped GST alloys
Published 2019“…For (GST)<sub>0.85</sub>As<sub>0.15</sub>, V<sub>T</sub> is about 5.2 V, which is higher than GST (4.0 V). …”
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Analysis of Innovative Vapor Compression and Thermal Energy Storage Systems Using Alternative Refrigerants
Published 2016Get full text
doctoralThesis -
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Dietary Trichosporon mycotoxinivoron modulates ochratoxin-A induced altered performance, hepatic and renal antioxidant capacity and tissue injury in broiler chickens
Published 2021“…<p dir="ltr">Ochratoxin A (OTA), an important fungal metabolite in foods and feeds has been shown to induce oxidative stress and cellular injuries to human and animal subjects. …”
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COVID-19 and Anemia: What Do We Know So Far?
Published 2023“…<p dir="ltr">On 11 March 2020, the World Health Organization (WHO) declared the novel SARS-CoV-2 virus responsible for causing COVID-19, a global pandemic. …”
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Layered homologous compounds (ZnO)<sub><em>k</em></sub>In<sub>2</sub>O<sub>3</sub> (<i>k</i> = 3, 5, and 7) as novel photocatalysts for visible-light-driven photocatalytic degradat...
Published 2024“…UV–vis spectroscopy revealed the band gap widening with increasing ‘<i>k</i>’, while IZO-5 and IZO-7 exhibit lower PL emissions in the visible range. …”
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Therapeutic targeting of the TPX2/TTK network in colorectal cancer
Published 2023“…<h3>Background</h3><p dir="ltr">While the increased screening, changes in lifestyle, and recent advances in treatment regimen have decreased colorectal cancer (CRC) mortality, metastatic disease and recurrence remains a major clinical challenge. …”
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An Experimental Investigation of R134a Clathrates with Liquid Additives
Published 2016Get full text
doctoralThesis -
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Generalized and pregnancy-related anxiety prevalence and predictors among pregnant women attending primary health care in Qatar, 2018–2019
Published 2020“…</p><h3>Results</h3><p dir="ltr">Out of eight hundred participants, 26.5% reported high pregnancy-related anxiety, while 16.4% had a generalized anxiety disorder. …”