A modified lipid composition in Fabry disease leads to an intracellular block of the detergent-resistant membrane-associated dipeptidyl peptidase IV by Rizk, Sandra

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mTORC1 loss impairs epidermal adhesion via TGF-b/Rho kinase activation by Georgess, Dan

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Graph-Guided Regularized Regression of Pacific Ocean Climate Variables to Increase Predictive Skill of Southwestern U.S. Winter Precipitation by Tejedor, Alejandro

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Positive regulation of oxidative phosphorylation by nuclear myosin 1 protects cells from metabolic reprogramming and tumorigenesis in mice by Tomas Venit (17248420)

“…<p dir="ltr">Metabolic reprogramming is one of the hallmarks of tumorigenesis. Here, we show that nuclear myosin 1 (NM1) serves as a key regulator of cellular metabolism. …”

Urinary Metabolomic Markers of Protein Glycation, Oxidation, and Nitration in Early-Stage Decline in Metabolic, Vascular, and Renal Health by Jinit Masania (7164239)

“…We recruited 200 human subjects with early-stage health decline and healthy controls. …”

ACTB Loss-of-Function Mutations Result in a Pleiotropic Developmental Disorder by Sara Cuvertino (18892069)

“…Fibroblasts derived from an affected individual and <i>ACTB</i> siRNA knockdown in wild-type fibroblasts showed altered cell shape and migration, consistent with known roles of cytoplasmic β-actin. We also demonstrate that <i>ACTB</i> haploinsufficiency leads to reduced cell proliferation, altered expression of cell-cycle genes, and decreased amounts of nuclear, but not cytoplasmic, β-actin. …”

Correlating process parameters to thrust forces and torque in the friction stir processing of AZ31B by Ammouri, Ali

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Structural performance of buried prestressed concrete cylinder pipes with harnessed joints interaction using numerical modeling by Hajali, Masood

“…The results show that the internal fluid pressure required to cause failure can be as much as 34% lower when the damage is at the barrel of the pipe, and that the internal pressure that causes yielding of the wire wraps decreases by 66% as the damage worsens from 5 to 100 wire breaks.…”
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Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro by Najem, Sonia A.

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Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice by Ayman Alzu'bi (18192898)

“…These findings were found to be correlated with increased level of <u>oxidative stress, neuroinflammation,</u> and apoptosis markers, and reduced expression of brain-derived neurotrophic factor (BDNF), which plays an essential role in modulating <u>synaptic plasticity</u> integral for promoting learning and memory in the hippocampus. Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …”

Epstein–Barr Virus Epidemiology, Serology, and Genetic Variability of LMP-1 Oncogene Among Healthy Population: An Update by Maria K. Smatti (4675852)

“…Here, we provide a review of the EBV epidemiology and the genetic variability of the oncogene LMP-1. …”

Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017 by LBD Double Burden of Malnutrition Collaborators (18567880)

“…</p><h2>Other Information</h2><p dir="ltr">Published in: Nature Medicine<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1038/s41591-020-0807-6" target="_blank">https://dx.doi.org/10.1038/s41591-020-0807-6</a></p>…”

Investigating the Quality Combined Effect of Root Cause Analysis (RCA) in Quality Management in Manufacturing Firms by ALBLOOSHI, ROUDHA KHALID ABDULLA

“…By employing tools such as flowcharts, fishbone diagrams, and statistical analysis, the research pinpointed the inadequate 4KV surge protection as a primary defect contributor. Implementing a 6KV surge protector for higher-wattage lights significantly reduced defect rates by 0.5%. …”
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Research on the potential of photovoltaic technologies in reducing energy consumption in an urban mixed use residential community. A Case study for net zero energy community in Dub... by SUGATHAN, SANAL

“…Reaching net zero energy (NZE) status across every single building may not be feasible, but it is realistic if we evaluate them with their connected systems as a collective unit at the community scale. …”
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The cost-benefit associated with the maturity of the Antimicrobial Stewardship Program versus prematurity in Heart Hospital of Hamad Medical Corporation in Qatar by Dina Abushanab (10696501)

Effects of Different Processing Methods on the Antibiotic Enrofloxacin Residues Occurrence in Middle Eastern Dairy Products by Haddad, Rita

“…Results showed that pasteurization (Holder and High Temperature Short Time) significantly decreased ENF concentration. A significant increase in ENF by 3.5 folds was reported upon curding milk into Baladi, and by 1.9 folds upon acidifying/boiling the whey into Double Crème. …”
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The Effect of Treated Waste-Water on Compaction and Compression of Fine Soil by Attom, Mousa

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Investigating the mechanism by which the platelet-derived growth factor receptor promotes metastasis in medulloblastoma by AbouAntoun, Thamara Jihad

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On the sampling and integration rates of process noise by Saab, Samer S.

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Optimal load distribution for the detection of VM-based DDoS attacks in the cloud by Abdel Wahab, Omar

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