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Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
Published 2023“…In this study, we examined various approaches to elevate SLFN11 expression in breast cancer cellular models and confirmed a corresponding increase in chemosensitivity with using the most successful efficient one. …”
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Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma
Published 2020“…The aim of this study was to evaluate the oncostatic activities of Rhus coriaria L. (sumac) using animal models (rat and mouse), and cell lines of breast carcinoma. …”
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Temporal patterns of cancer burden in Asia, 1990–2019: a systematic examination for the Global Burden of Disease 2019 study
Published 2024“…Tracheal, bronchus, and lung cancer (both sexes), breast cancer (among females), colon and rectum cancer (both sexes), stomach cancer (both sexes) and prostate cancer (among males) were among top-5 cancers in most Asian countries in terms of ASIR and ASMR in 2019 and cancers of liver, stomach, hodgkin lymphoma and esophageal cancer posted the most significant decreases in age-standardized rates between 1990 and 2019. …”
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β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo
Published 2017“…Cisplatin (2.5 mg/kg; IP) was used as a positive control. Papilloma incidence, yield and volume were monitored, and isolated papillomas were assessed for their pro/anti-apoptotic proteins and morphology. …”
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Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways
Published 2017“…Cell cycle analysis was carried out by flow cytometry, and pro/anti-apoptotic proteins were measured using western blot. The effect of intraperitoneal (IP) treatment with HC (10, 25 and 50 μg/ml) in mice was assessed using the DMH colon carcinogenesis model with Cisplatin (2.5 μg/kg; IP) as a positive control. …”
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The antioxidant and anticancer effects of Wild Carrot oil extract
Published 2012“…Also, DCOE demonstrated a significant increase in cell death and decrease in cell proliferation. …”
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Oral contraceptive pills and possible adverse effects
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Palladin Regulates Invadopodia Formation in Glioblastoma
Published 2021“…The results show an increase in invadopodia as seen by TKS4 and TKS5 staining as well as a decrease in Cdc42 activity following palladin knockdown. …”
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Interactions between riluzole and ABCG2/BCRP transporter
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Chemical characterization and cytotoxic activity evaluation of Lebanese propolis
Published 2017“…Chemical composition, anti-proliferative and proapoptotic activity as well as the effect of various fractions of Lebanese propolis on the cell cycle distribution were evaluated on Jurkat leukemic T-cells, glioblastoma U251 cells, and breast adenocarcinoma MDA-MB-231 cells using cytotoxic assays, flow cytometry as well as western blot analysis. …”
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P-glycoprotein expression and function are increased in an animal model of amyotrophic lateral sclerosis
Published 2010“…In the present study, we used a transgenic mouse model of ALS (G86R mSOD1 mice) to test this hypothesis. …”
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