Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle حسب Jinit, Masania

"…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neurons حسب Wesal Habbab (17346961)

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex حسب Wesam S. Ahmed (10170053)

"…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…"

Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex حسب Wesam S. Ahmed (10170053)

"…<p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences <a href="https://dx.doi.org/10.3389/fmolb.2022.846996" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.846996</a>, published online 22 July 2022.…"

Effect of Mg incorporation on the properties of PCL/Mg composites for potential tissue engineering applications حسب Sumama Nuthana Kalva (19206064)

"…However, the elastic modulus decreased by around 50% for the same composition. The thermal study revealed a significant reduction in the degradation temperature from above 400°C for pure PCL to around 300°C for PCL/Mg composite having 15% Mg. …"

Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies حسب Fawaz E., Alanazi

"…Melanoma is an aggressive skin cancer with a high rate of metastasis to other organs. Recent studies specified the overexpression of V-domain Ig suppressor of T-cell activation (VISTA) and Aryl Hydrocarbon Receptor (AHR) in melanoma. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov... حسب Salma, Younes

"…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Impact of trace noble metals on the catalytic performance of LaNiMgO towards methane dry reforming حسب Mohamed, Assem T.

"…On the other hand, at the same time-on-stream LaNiMgO-Rh lost 0.3 and 0.7 % of its maximum CO2 and CH4 conversions, respectively.In durability measurements, and after 140h LaNiMgO-Rh exhibited slight decay in the CO2 conversion from 77.6 % to 70.5%, the CH4 conversion decreased from 72.3% to 64.2%. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Impact of trace noble metals on the catalytic performance of LaNiMgO towards methane dry reforming حسب Yahia H. Ahmad (14340210)

"…In durability measurements, and after 140h LaNiMgO-Rh exhibited slight decay in the CO₂ conversion from 77.6 % to 70.5%, the CH₄ conversion decreased from 72.3% to 64.2%. …"

A genetically encoded BRET-based SARS-CoV-2 Mpro protease activity sensor حسب Anupriya M. Geethakumari (17052375)

"…Further, in vitro assays with the BRET-based Mpro sensors revealed a molecular crowding-mediated increase in the rate of M^pro activity and a decrease in the inhibitory potential of GC376. …"

Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis حسب Maria K. Smatti (4675852)

"…</p><h3>Results</h3><p dir="ltr">A total of 74 SNPs, located in 10 genes: ICAM3, IFN-γ, CCL2, CCL5, AHSG, MBL, Furin, TMPRSS2, IL4, and CD209 promoter, were identified. …"

Theoretical and experimental insights into the C-steel aqueous corrosion inhibition at elevated temperatures in 1.0 M HCl via multi-carbonyl Gemini cationic surfactants حسب Nasser M. El-Basiony (18021631)

Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells حسب Mohamed Qasim, Al-Fahdawi

"…The cytotoxicity of Pt/MgO nanoparticles was determined via the 3-(4,5-dimethylthiazol-2-yl)−2,5-diphenyltetrazolium bromide assay on the human lung and colonic cancer cells (A549 and HT29 respectively) and normal human lung and colonic fibroblasts cells (MRC-5 and CCD-18Co repectively). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... حسب Vijay Ganji (8710491)

BRET-based biosensors for SARS-CoV-2 oligonucleotide detection حسب Asfia Sultana (19170880)

"…Specifically, we designed BioODs against the SARS-CoV-2 parental (Wuhan strain) and B.1.617.2 Delta variant through the conjugation of specific, fluorescently modified molecular beacons (sensor module) through a complementary oligonucleotide handle DNA functionalized with the NanoLuc (NLuc) luciferase protein such that the dissolution of the molecular beacon loop upon the binding of the viral oligonucleotide will result in a decrease in BRET efficiency and, thus, a change in the bioluminescence spectra. …"

There Is Selective Increase in Pro-thrombotic Circulating Extracellular Vesicles in Acute Ischemic Stroke and Transient Ischemic Attack: A Study of Patients From the Middle East an... حسب Abdelali Agouni (181926)

"…Compared to controls, there was also an increase in EVs derived from activated endothelial cells, platelets, granulocytes, leukocytes, and pro-coagulant EVs (Annexin V⁺) at 5 and 30-days following the acute events, while a decrease was observed in erythrocyte-derived EVs. …"

Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications حسب Jingxuan Shan (4711089)

"…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …"

A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate حسب Geethakumari, Anupriya M

"…Here, we report the engineering of a Bioluminescence Resonance Energy Transfer (BRET)-based SARS-CoV-2 main protease (Mpro) biosensor containing the Mpro N-terminal autocleavage sequence in tandem and a nanobody that shows an enhanced rate of Mpro-mediated proteolytic cleavage. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Global, regional, and national burden of household air pollution, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 حسب Fiona B, Bennitt

"…Using a systematic review of the epidemiological literature and a newly developed meta-regression tool (meta-regression: Bayesian, regularised, trimmed), we derived disease-specific, non-parametric exposure–response curves to estimate relative risk as a function of PM2·5 concentration. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Ferroelectric Properties and Electrocaloric Effect in Dy2O3 Substitution on Lead-Free (Na0.5 Bi0.5)0.94 Ba0.06TiO3 Ceramic حسب Turki, O.

"…Using the direct EC measurement, the ceramic corresponding to y = 0.02 exhibited a significant EC response, where ΔT = 1.2 K under 5 kV/mm. …"
احصل على النص الكامل