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BRET-based biosensors for SARS-CoV-2 oligonucleotide detection
Published 2024“…Specifically, we designed BioODs against the SARS-CoV-2 parental (Wuhan strain) and B.1.617.2 Delta variant through the conjugation of specific, fluorescently modified molecular beacons (sensor module) through a complementary oligonucleotide handle DNA functionalized with the NanoLuc (NLuc) luciferase protein such that the dissolution of the molecular beacon loop upon the binding of the viral oligonucleotide will result in a decrease in BRET efficiency and, thus, a change in the bioluminescence spectra. …”
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Non-diabetic ketoacidosis secondary to primary hyperthyroidism
Published 2022“…One infrequent complication of hyperthyroidism is non-diabetic ketoacidosis (NDKA). To the best of our knowledge, our case is the third report of NDKA related to thyrotoxicosis.…”
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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
Published 2025“…We envisage that the NB2E3 nanobody-2× Mpro biosensor engineered here will be useful in drug discovery and functional characterization of Mpro mutants in newly emerging SARS-CoV-2 variants as well as in detecting SARS-CoV-2 infection in a point-of-care testing (POCT) format.…”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…”
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The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR)
Published 2023“…These results reiterate the decisive role of 5-Aza-CdR in lung cancer treatment since it induces the epigenetic regulation of NY-ESO-1 antigen, inhibits cell proliferation, increases apoptosis, and decreases invasiveness.…”
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The impact of climatic conditions on the carcinogenic and non-carcinogenic risk of BTEX compounds: A systematic review and meta-analysis
Published 2024“…For different climatic conditions, the overall mean and 95 % confidence interval (CI) of the effect size related to the carcinogenic and non-carcinogenic risk of BTEX were calculated using a random effect model. 26 articles passed the inclusion/exclusion criteria and were included in this review. …”
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Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex
Published 2022“…<p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences <a href="https://dx.doi.org/10.3389/fmolb.2022.846996" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.846996</a>, published online 22 July 2022.…”
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Effect of Intravenous Mannitol on Intraocular Pressure Changes in Vitrectomized and Non-Vitrectomized Eyes: A Systematic Review and Meta-Analysis
Published 2024“…Meta-analysis was performed using a random-effects model. R software (V 4.3) was used for statistical analysis.…”
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Effect of carbon nanotubes on the bonding mechanism of non-corrosive reinforcements to concrete
Published 2024“…This study aimed to assess the impact of waterborne pre-dispersed multiwall carbon nanotubes (MWCNTs) at a concentration of 0.2 wt % on the bond strength between concrete and non-corrosive reinforcements, including stainless steel (SS), glass fiber reinforced polymers (GFRP), and basalt fiber reinforced polymers (BFRP) bars. …”
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Effect of carbon nanotubes on the bonding mechanism of non-corrosive reinforcements to concrete
Published 2024“…<p>This study aimed to assess the impact of waterborne pre-dispersed multiwall carbon nanotubes (MWCNTs) at a concentration of 0.2 wt % on the bond strength between concrete and non-corrosive reinforcements, including stainless steel (SS), glass fiber reinforced polymers (GFRP), and basalt fiber reinforced polymers (BFRP) bars. …”
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A CFD- RSM study of cuttings transport in non-Newtonian drilling fluids: Impact of operational parameters
Published 2022“…The current article provides a theoretical study of the impact of three operational parameters on cuttings transport in non-Newtonian drilling fluids. …”
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Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study
Published 2020“…Best practice guidelines should be developed for improved medical practice in the prescription of medications for such a vulnerable population.</p><p dir="ltr">Correction: Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study <a href="https://doi.org/10.1371/journal.pone.0238343" target="_blank">https://doi.org/10.1371/journal.pone.0238343</a>, published online 24 August 2020.…”
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Drying Studies of Purple Non-Sulphur Bacterial Biomass and Application as a Single-Cell Protein Feed for <i>Litopenaeus vannamei</i>
Published 2024“…In this regard, single-cell protein (SCP) has emerged as an attractive opportunity due to its high productivity rate and lack of competition with arable land. Purple non-sulphur bacteria (PNSB) are one organism with a strong potential for single-cell protein. …”
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Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas
Published 2019“…</p><p dir="ltr"><br></p><h3>Precis: </h3><p dir="ltr">CPHN cell frequency declines steeply from fetal to infant life, as they mature to hormone expression. CPHN cells represent a non-replicative pool of endocrine precursor cells, a proportion of which are likely fated to become beta-cells.…”
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Effective non-intrusive load monitoring of buildings based on a novel multi-descriptor fusion with dimensionality reduction
Published 2020“…This paper presents an efficient non-intrusive load monitoring framework that consists of the following main components: (i) a novel fusion of multiple time-domain features is proposed to extract appliance fingerprints; (ii) a dimensionality reduction scheme is introduced to be applied to the fused time-domain features, which relies on fuzzy-neighbors preserving analysis based QR-decomposition. …”
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Correction: Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study
Published 2020“…<p dir="ltr">Correction to: Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study. …”
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Determinants of Non-Performing Loans in the State of Qatar With Special References to Small and Medium Enterprises
Published 2024“…The findings regarding borrower-specific factors include high-interest rates, overhead costs, public procurement, economic and government policies & regulations, and a highly competitive market influencing the non-payment of loans. …”