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decrease » decreased (Expand Search), increase (Expand Search)
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…Melanoma is an aggressive skin cancer with a high rate of metastasis to other organs. Recent studies specified the overexpression of V-domain Ig suppressor of T-cell activation (VISTA) and Aryl Hydrocarbon Receptor (AHR) in melanoma. …”
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Therapeutic targeting of the TPX2/TTK network in colorectal cancer
Published 2023“…Additionally, gene-drug interaction analysis identified several druggable gene targets enriched in the TPX<sub>2</sub>/TTK network, including AURKA, TOP<sub>2</sub>A, CDK1, BIRC<sub>5</sub>, and many others.</p><h3>Conclusions</h3><p dir="ltr">Our data has implicated an essential role for TPX2 and TTK in CRC pathogenesis and identified numerous potential therapeutic targets and their drug interactions, suggesting their potential clinical use as a novel therapeutic strategy for patients with CRC.…”
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Generalized and pregnancy-related anxiety prevalence and predictors among pregnant women attending primary health care in Qatar, 2018–2019
Published 2020“…</p><h3>Results</h3><p dir="ltr">Out of eight hundred participants, 26.5% reported high pregnancy-related anxiety, while 16.4% had a generalized anxiety disorder. …”
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Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis
Published 2020“…</p><h3>Results</h3><p dir="ltr">A total of 74 SNPs, located in 10 genes: ICAM3, IFN-γ, CCL2, CCL5, AHSG, MBL, Furin, TMPRSS2, IL4, and CD209 promoter, were identified. …”
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The effects of long-term testosterone treatment on endocrine parameters in hypogonadal men: 12-year data from a prospective controlled registry study
Published 2022“…We observed an increase in TT of 15.5 nmol/L (<i>p</i> < 0.0001), a reduction in SHBG of 10.5 nmol/L (<i>p</i> < 0.0001) and an increase in calculated free T of 383.04 pmol/L (<i>p</i> < 0.0001) over the study period. …”
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Cardiorespiratory Fitness and Performance Adaptations to High-Intensity Interval Training: Are There Differences Between Men and Women? A Systematic Review with Meta-Analyses
Published 2023“…Meta-analyses included 19 studies for V̇ O<sub>2max</sub>, eight for peak power output from V̇ O<sub>2max</sub> testing (PPO), and five for threshold power (powerAT). …”
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Wales’ tourists not a burden for local healthcare
Published 2016“…</p><p>Instead, they found that Welsh residents were responsible for the vast majority of unintentional injury presentations to the emergency department. They also found a decrease in non-resident presentations between 2006 and 2014, the data range that was studied.…”
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Meta-Heuristic Algorithm-Tuned Neural Network for Breast Cancer Diagnosis Using Ultrasound Images
Published 2022“…Over the decade, numerous artificial neural network (ANN)-based techniques were adopted in order to diagnose and classify breast cancer due to the unique characteristics of learning key features from complex data via a training process. However, these schemes have limitations like slow convergence and longer training time. …”
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A decision support system for automating document retrieval and citation screening
Published 2021“…<p dir="ltr">The systematic literature review (SLR) process includes several steps to collect secondary data and analyze it to answer research questions. …”
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A Multidecadal Assessment of Haze Development and Fluctuations in Visibility for Arabian Peninsula
Published 2024“…Visibility in KWT was 0.5 km in 1994, indicating a period of exceptionally poor visibility whereas the daily mean visibility for KSA was approximately 0.6 km. …”
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Financial Performance of Islamic and Conventional Banks in Oman: A Comparative Analysis
Published 2021“…The performance assessment of banks aims to ensure that the resources at their disposal are used effectively. It is a systematic process in which all the records, accounting, and other data are taken into account. …”
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Association Between Serum Bicarbonate Levels and Prediabetes and Subclinical Inflammation in Young Healthy Adults: A Cross-sectional Study
Published 2023“…</p><h3>Results</h3><p dir="ltr">A total of 825 participants with mean age 29.2 years (5.9) of which 365 (44.2%) were males. …”
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Football-induced fatigue in hypoxia impairs repeated sprint ability and perceptual-cognitive skills
Published 2019“…RS were affected by football-induced fatigue for DC (4.8%;ES=0.68) and AV (5.5%;ES=0.79). In hypoxia, a 6.5% was found for DC, 6.3% for AV and 3.1% for PV at 1500-m compared to 0-m (P<0.05). …”
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Hypoglossal nerve stimulation for obstructive sleep apnea in adults: An updated systematic review and meta-analysis
Published 2024“…Patient-reported outcomes showed decreased Epworth Sleepiness Scale (ESS) scores by −5.02 (short term) and −4.90 (long term) and improved Functional Outcomes of Sleep Questionnaire (FOSQ) scores by 3.58 (short term) and 3.28 (long term). …”
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Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension
Published 2023“…There was no significant difference in the mean initial blood glucose between neonates in the hypertensive versus non-hypertensive groups of mothers (1.7 vs 1.6 mmol/L). However, a sub-group comparison of neonates (with initial blood glucose <2.6 mmol/L) showed methyldopa to be marginally associated with a 2 mmol/L decrease from the mean initial blood glucose, mean 1.6 ± 0.5 mmol/L, and methyldopa (1.4 ± 0.5 mmol/L; p= .045). …”
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Maternal Body Mass Index and Recommended Gestational Weight Gain in a Middle Eastern Setting
Published 2023“…</p><h3>Methods</h3><p dir="ltr">We performed a population-based retrospective cohort analysis of 3547 singleton births, using routinely collected data from a Middle Eastern hospital database.…”