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Therapeutic targeting of the TPX2/TTK network in colorectal cancer
منشور في 2023"…<h3>Background</h3><p dir="ltr">While the increased screening, changes in lifestyle, and recent advances in treatment regimen have decreased colorectal cancer (CRC) mortality, metastatic disease and recurrence remains a major clinical challenge. …"
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A potential therapeutic agent for sickle cell anaemia
منشور في 2016"…Also, supplementing patients with substances that possess antioxidant properties could reduce the complications of the disease,” says biochemist Lamia Al-Naama, the lead author of the paper. Substances that decrease the frequency of episodes of red blood cell destruction or employing molecular approaches that can reduce ROS production could alter the course of the disease and the incidence of associated complications, she adds.…"
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Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study
منشور في 2020"…<h3>Background </h3><p dir="ltr">Polypharmacy has become a global public health concern particularly in the elderly population. …"
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Correction: Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study
منشور في 2020"…<p dir="ltr">Correction to: Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study. <a href="https://doi.org/10.1371/journal.pone.0234386" target="_blank">https://doi.org/10.1371/journal.pone.0234386</a>, published online 11 June 2020.…"
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Comparison of Burr-Hole Craniostomy versus Twist-Drill Craniostomy Operations for Patients with Chronic Subdural Hematoma: A Systematic Review and Network Meta-Analysis
منشور في 2023"…</p><h2>Other Information</h2><p dir="ltr">Published in: World Neurosurgery<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.wneu.2023.05.022" target="_blank">https://dx.doi.org/10.1016/j.wneu.2023.05.022</a></p>…"
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Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2...
منشور في 2024"…From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20·7% [13·9–27·7]) and environmental and occupational risks (decrease of 22·0% [15·5–28·8]), coupled with a 49·4% (42·3–56·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. …"
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Association Between Serum Bicarbonate Levels and Prediabetes and Subclinical Inflammation in Young Healthy Adults: A Cross-sectional Study
منشور في 2023"…</p><h3>Results</h3><p dir="ltr">A total of 825 participants with mean age 29.2 years (5.9) of which 365 (44.2%) were males. …"
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Outcomes of POCUS‐Guided Peripheral Intravenous Access in Difficult Venous Access Patients: A Systematic Review and Meta‐Analysis
منشور في 2025"…A systematic review of 15 studies with 1485 patients, sourced from five databases, including PubMed, Cochrane Library, MEDLINE, Web of Science, and Google Scholar, showed POCUS significantly improved success rates (OR: 4.25), first‐attempt success (OR: 5.31), reduced attempts (MD: −0.83), and decreased procedure time (MD: −9.75 min). …"
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Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension
منشور في 2023"…There was no significant difference in the mean initial blood glucose between neonates in the hypertensive versus non-hypertensive groups of mothers (1.7 vs 1.6 mmol/L). However, a sub-group comparison of neonates (with initial blood glucose <2.6 mmol/L) showed methyldopa to be marginally associated with a 2 mmol/L decrease from the mean initial blood glucose, mean 1.6 ± 0.5 mmol/L, and methyldopa (1.4 ± 0.5 mmol/L; p= .045). …"
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Prevalence of bullying and violence among adolescents in Arab Gulf countries: a systematic review
منشور في 2025"…</p><h3 dir="ltr">Subject and methods</h3><p dir="ltr">We conducted a comprehensive search across PubMed, EMBASE, Scopus, and Web of Science databases from inception to April 2025. …"
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Particle size impact on pyrolysis of multi-biomass: a solid-state reaction modeling study
منشور في 2023"…Both activation energy and pre-exponential factor decreased from 18.78 to 5.57 kJ/mol and 1.16 E+10 to 1.48 E+08 with reducing particle sizes. …"
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Maternal Body Mass Index and Recommended Gestational Weight Gain in a Middle Eastern Setting
منشور في 2023"…</p><h3>Results</h3><p dir="ltr">The mean maternal age was 29.7 ± 5.5 years, prepregnancy BMI was 27.5 ± 5.8 kg/m2, GWG was 9.58 kg ± 6.87 kg and gestational age at birth was 38.5 ± 1.9 weeks. …"
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Solar Technology and District Cooling System in a Hot Climate Regions: Optimal Configuration and Technology Selection
منشور في 2022"…The PVT-DCS configuration has the lowest operation cost and the highest environmental performance by decreasing the global warming potential by 89.5%. The T-DCS configuration becomes economically competitive only at high electricity tariffs.…"
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Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity
منشور في 2013"…Using this approach, a total of 47 proteins showed at least 1.5 fold change between lean and obese subjects. …"
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Efficacy and safety of the newer oral hypoglycemic agents in patients with T2DM during Ramadan: A systematic review and meta-analysis
منشور في 2020"…Glucagon-like peptide (GLP-1) agonist therapy was associated with a significant decrease in Hb<sub>A1c</sub> (%) (SMD -0.68) and a non-significant decrease in weight (kg) (SMD -2.57) and systolic blood pressure (SBP) (mmHg) (SMD -3.50) after Ramadan. …"