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601
Characterizing the Protein Coding RNAs (mRNA) and Long Non-Coding RNAs (LncRNAs) in Chemo Resistant Triple Negative Breast Cancer
Published 2023“…Although, death rates due to BC have consistently decreased over time, TNBC still poses a challenge due to its poor prognosis, high rates of relapse and resistance to chemotherapy. …”
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602
Trends in criminal convictions in Japan for vehicle collisions where one driver suffers from an epileptic seizure
Published 2015“…<p dir="ltr">For the last fourteen years in Japan, casualties due to traffic collisions have decreased. There were 9,073 traffic fatalities in 2000 and 4,113 in 2014. …”
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603
Understanding the Molecular Mechanisms of Dysglycemia in Patients with Fanconi-Bickel Syndrome
Published 2023“…It is inherited in an autosomal recessive manner due to<i> SLC2A2 </i>gene mutations. <i>SLC2A2</i> encodes for glucose transporter 2 (GLUT2) which is a low-affinity facilitative transporter of glucose; it is mainly expressed in tissues that are significantly involved in glucose homeostasis. …”
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604
Understanding the Mechanism of Diabetes Mellitus in LRBA-Deficient Patient
Published 2023“…However, aggregates related to CD71+ erythroid cells, which have immunosuppressive characteristic, were highly upregulated in the LRBA-deficient patients.Experimental analysis of MIN6 cell in culture revealed that in siRNA-mediated-knockdown of LRBA revealed a significant decreased intracellular proinsulin and mature insulin inside β-cells in comparison so the wild type cells. …”
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605
Immunoprofile of childhood diabetes
Published 2023“…</p> <p>Methods: Here we collected transcriptomic and metabolomic data from 86 children under 17 years-old to identify the regulatory events that participate in IR development. A comparative analysis of the transcriptome of the two major subtypes of CD4+ T cells, regulatory-T cells (Treg) and conventional T cells (Tcon) was conducted and compared with the plasma metabolome of 14 Control, 19 Obese, 17 Pre-diab, 16 T2D, and 20 T1D cases. …”
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606
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607
Frugal innovation for sustainable rural development
Published 2023“…We developed a classification that identifies the increasing positive and decreasing negative parameters of SDGs to assess the extent to which frugal enterprises contribute to specific SDGs. …”
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608
Frugal innovation for sustainable rural development
Published 2023“…We developed a classification that identifies the increasing positive and decreasing negative parameters of SDGs to assess the extent to which frugal enterprises contribute to specific SDGs. …”
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609
The immune landscape of solid pediatric tumors
Published 2022“…</p><h3>Methods</h3><p dir="ltr">We performed a systematic analysis of public RNAseq data (TARGET) for five pediatric tumor types (408 patients): Wilms tumor (WLM), neuroblastoma (NBL), osteosarcoma (OS), clear cell sarcoma of the kidney (CCSK) and rhabdoid tumor of the kidney (RT). …”
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610
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611
Non-Isolated DC–DC Power Converter With High Gain and Inverting Capability
Published 2021“…The parasitic of the components has been considered in the analysis to show the deviation from the ideal cases. A detailed comparison with the other available converters is presented. …”
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612
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Driving and hypoglycemia
Published 2015“…Hypoglycemia has been associated with cardiac arrhythmia, a decreased ability to drive and driving mishap. …”
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614
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Fibrillar form of α-synuclein-specific scFv antibody inhibits α-synuclein seeds induced aggregation and toxicity
Published 2020“…In vitro studies indicated scFvs inhibit the seeding of α-syn aggregation in a time-dependent manner, decreased α-syn seed-induced toxicity in a cell model of PD, and reduced the production of insoluble α-syn phosphorylated at Ser-129 (pS129-α-syn). …”
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616
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Comparative Genomic Mapping Implicates LRRK2 for Intellectual Disability and Autism at 12q12, and HDHD1, as Well as PNPLA4, for X-Linked Intellectual Disability at Xp22.31
Published 2020“…Using another affected member, DGDP289B, with a microdeletion at Xp22.31, in this family, we performed the genomic and clinical delineation with six published and nine unreported cases. …”
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618
Small molecule inhibitors of α-synuclein oligomers identified by targeting early dopamine-mediated motor impairment in C. elegans
Published 2021“…<h3>Background</h3><p dir="ltr">Parkinson’s disease is a disabling neurodegenerative movement disorder characterized by dopaminergic neuron loss induced by α-synuclein oligomers. …”
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