Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic... حسب Muhanad Alhujaily (11630107)

"…<h3>Background</h3><p dir="ltr">Tumor glycolysis is a target for cancer chemotherapy. Methylglyoxal (MG) is a reactive metabolite formed mainly as a by-product in anaerobic glycolysis, metabolized by glyoxalase 1 (Glo1) of the glyoxalase system. …"

Appropriateness of gentamicin therapeutic drug monitoring at a Middle Eastern tertiary hospital setting: a retrospective evaluation and quality audit حسب Fatima Khalifa Al-Sulaiti (14152056)

"…</p><h3>Objective</h3><p dir="ltr">This study aimed to evaluate the appropriateness of gentamicin therapeutic drug monitoring (TDM) at a tertiary care hospital in Qatar.</p><h3>Methods</h3><p dir="ltr">A one-year quantitative retrospective chart review of all gentamicin TDM records was conducted. …"

Correction: Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study حسب Ayman Al-Dahshan (8962568)

"…<p dir="ltr">Correction to: Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study. <a href="https://doi.org/10.1371/journal.pone.0234386" target="_blank">https://doi.org/10.1371/journal.pone.0234386</a>, published online 11 June 2020.…"

High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis حسب Nabil, Shallik

"…HFNO was associated with a significant decrease in mortality and intubation rates (0.28 (95% CI; 0.19, 0.39) and 0.28 (95% CI; 0.18, 0.41), respectively). …"
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High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis حسب Nabil Shallik (15900256)

"…HFNO was associated with a significant decrease in mortality and intubation rates (0.28 (95% CI; 0.19, 0.39) and 0.28 (95% CI; 0.18, 0.41), respectively). …"

Thermodynamic Analysis of Gravity Assisted Solar-Powered Reverse Osmosis Unit for Greenhouses Situated in a Depleted Zone with Performance Evaluation and Improvements Using Nanoflu... حسب Yasser Mohamed Mohamed Taher Abdellatif (20741534)

"…<p dir="ltr">The Sabkha-Tah region of Western Sahara is a location where adverse weather conditions make it difficult for certain crops' conventional farming. …"

MHD Heat Transfer Enhancement in a Curvilinear Enclosure With Oscillating Wall and Nano‐Encapsulated PCM: A Fluid‐Structure Interaction Analysis حسب Mohammed Azeez Alomari (20482592)

"…</p><h2>Other Information</h2><p dir="ltr">Published in: Heat Transfer<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1002/htj.23399" target="_blank">https://dx.doi.org/10.1002/htj.23399</a></p>…"

Feasibility of a group-based laughter yoga therapy on anxiety and happiness among community-dwelling older adults: A quasi-experimental study حسب Mona Metwally El-Sayed (17725127)

"…</p><p><br></p><h3>Results</h3><p dir="ltr">A statistically significant decrease in anxiety level among the study group compared to the control group (Pre = 16.68 (7.35), immediate = 6.65 (2.89), post three-month = 7.68 (2.75), p=<0.001 and effect size = 0.715). …"

The impact of metformin therapy for gestational diabetes on fetal growth in women with risk factors for fetal growth restriction- a registry-based study from Qatar حسب Komal Rafique (17075074)

"…<h3>Background</h3> <p>Gestational diabetes mellitus (GDM) has been the most prevalent medical condition in pregnancy, often managed by a multidisciplinary team. Numerous studies have demonstrated that metformin therapy for GDM offers advantages including a reduced risk of macrosomia, neonatal hypoglycemia, and admission to neonatal intensive care units (NICU). …"

Diabetes-related cardiovascular and economic burden in patients hospitalized for heart failure in the US: a recent temporal trend analysis from the National Inpatient Sample حسب Menatalla Mekhaimar (14103708)

"…Crude mortality gradually decreased from 2.7% in 2005 to 2.4% in 2014 but was still lower than that of non-diabetes patients’ mortality on a yearly comparison basis. …"

Resource recovery through bioremediation of fuel-synthesis wastewater in a biofilm photobioreactor using purple non-sulfur bacteria: A circular bioeconomy approach حسب Sultan Shaikh (19256497)

"…Specifically, the effects of four different FSW strengths (25–100 %) and nitrogen sufficiency (N⁺) or deficiency (N⁻) were evaluated in eight biofilm photobioreactors. This study observed a direct correlation between the concentration of FSW and PHB content; specifically, as the FSW content decreased from 100 % (undiluted) to 25 % the PHB content decreased. …"

Monitoring the Athlete Match Response: Can External Load Variables Predict Post-match Acute and Residual Fatigue in Soccer? A Systematic Review with Meta-analysis حسب Karim Hader (2548618)

"…For every 100-m run above 5.5 m·s⁻¹, CK activity measured 24 h post-match increased by 30% and CMJPPO decreased by 0.5%. …"

There Is Selective Increase in Pro-thrombotic Circulating Extracellular Vesicles in Acute Ischemic Stroke and Transient Ischemic Attack: A Study of Patients From the Middle East an... حسب Abdelali Agouni (181926)

"…Compared to controls, there was also an increase in EVs derived from activated endothelial cells, platelets, granulocytes, leukocytes, and pro-coagulant EVs (Annexin V⁺) at 5 and 30-days following the acute events, while a decrease was observed in erythrocyte-derived EVs. …"

The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 20... حسب Sudabeh Alatab (11257335)

"…The age-standardised rate of DALYs decreased from 26·5 (21·0–33·0) per 100 000 population in 1990 to 23·2 (19·1–27·8) per 100 000 population in 2017. …"

Genome-Wide Association Study of Vitamin D Deficiency in the Middle East With a Relevant Characterization of the Novel <i>SDR42E1 </i>Gene حسب Nagham Nafiz Ahmad Hendi (19938204)

"…Significant gene associations between the SDR42E1 and genes involved in Vitamin D pathways were identified, including alkaline phosphatase, placental type (ALPP), ATP-binding cassette C1 (ABCC1), solute carrier 7A5 (SLC7A5). Gene regulators of cellular senescence and cancer prognosis were found to be significantly affected after the knockout and knockout of SDR42E1 in HaCat and HCT116 cells. …"

A Quadratic Non-Isolated High Step-Up Single-Input Dual-Output DC–DC Topology Based on Coupled Inductors with Low Input Current Ripple حسب Vafa Marzang (17347048)

"…The proposed SIDO (or SISO) topology includes two CI, two independent switches, four (three) diodes, and five (four) capacitors. The proposed converter produces high DC output voltages at a low value of duty cycles and low voltage stress across the power MOSFETs. …"

A survey on communication technologies and requirements for internet of electric vehicles حسب Islam Safak Bayram (18421482)

"…<p>Electric vehicles (EVs) are becoming a more attractive transportation option, as they offer great cost savings, decrease foreign oil dependency, and reduce carbon emissions. …"

Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-... حسب Mohamed Yassin (4166515)

"…Real-world studies of crizanlizumab showed a reduction in complicated VOC events. The high discontinuation rate and results of the STAND trial led to a significant decrease in the use of crizanlizumab. …"

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 co... حسب Alize J, Ferrari

"…Non-communicable diseases contributed 1·73 billion (95% UI 1·54–1·94) DALYs in 2021, with a decrease in age-standardised DALY rates since 2010 of 6·4% (95% UI 3·5–9·5). …"
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Evaluating the Successful Initiation of a New Dialysate Potassium Management Protocol: “Reduced Emergency Department Admission with Hyperkalemia in Hamad General Hospital Dialysis... حسب Shajahan Joseph K (18472465)

"…</p><h3>Results</h3><p dir="ltr">ED admission of dialysis patients with hyperkalemia which require dialysis reduced from 12% to 0% (Figure 1) and the number of patients who are using low potassium bath of 1.0 mmol/L in Dialysate solution decreased from 56 in Jan 2022 to 7 patients in June 2023 (Figure 2)</p><h3>Conclusion </h3><p dir="ltr">The new potassium protocol was found to be very effective, and has a direct impact on the quality and safety of HD patients. …"