Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Pharmacological Mechanism of the Non-hallucinogenic 5‑HT_2A Agonist Ariadne and Analogs by Michael J. Cunningham (14267038)

“…Compared to DOM, Ariadne shows lower signaling potency and efficacy in multiple signaling pathways examined (G_q, G₁₁, and β-arrestin2) coupled to 5-HT_2A receptors. We confirmed the shift in signaling for an α-propyl analog and provide a molecular docking rationale for the progressive decrease in signaling potency with the growing length of the α-substituent. …”

Proposed model of miR-199a-5p profibrotic function in lung fibrogenesis. by Christian Lacks Lino Cardenas (282070)

“…Production of miR-199a-5p in response to TGFβ in lung fibroblasts results in CAV1 downregulation and subsequently, impaired TGFβ/TGFβR complex degradation. …”

Effects of H-80 infusion in the Central Medial thalamus nucleus (CM) on the Apparent Diffusion Coefficient (ADC), Local Field Potentials (LFPs) and awake response threshold. by Yoshifumi Abe (2577568)

Effects of furosemide infusion in the Central Medial thalamus nucleus (CM) on the Apparent Diffusion Coefficient (ADC), Local Field Potentials (LFPs) and awake response threshold u... by Yoshifumi Abe (2577568)

Fig 1 - by Natthaya Chuaypen (6726911)

Fig 2 - by Natthaya Chuaypen (6726911)

Calculation of braiding angle of internal cell A. by Weiliang Zhang (11231646)

Depletion of neutrophils is associated with a decreased number of CD4 T cells, B cells, eosinophils, DCs and MDSc during the chronic stages of <i>P</i>. <i>brasiliensis</i> infecti... by Juan David Puerta-Arias (3187089)

The principal coordinates analysis (PCoA) of different pig fecal samples including A1, A2, A3, A4, B5, B6, B7, and B8. by Shuai Huang (60512)

Table5_Kinematics and Aerodynamics of Dragonflies (Pantala flavescens, Libellulidae) in Climbing Flight.XLSX by Liansong Peng (11285773)

Statistics of predicted bandgaps by SVR, GBDT, RF and MLP algorithms based on a 9-dimensional feature space. by Yu Zhang (12946)

Early surface PSA-NCAM reduction induced by glutamate exposure. by María Fernanda Podestá (639243)

“…<p>Hippocampal neurons in culture (DIV 12–13) were briefly exposed to 5 µM glutamate and evaluated 1, 3 and 6 h later. …”

Effect of CoQ10 on blood levels of hematological parameters, lymphocyte percentage (LYM%), granulocytes percentage (GRA%), and medium size cells percentage of monocytes, eosinophil... by Yousif Jameel Jbrael (17797560)

Gene expression of chemokines and their receptors after spinal cord injury (SCI). by Kazumichi Yagura (4537504)

“…All data are expressed the relative level (fold) to compare with pod 0 (basal level) after normalization against <i>Gapdh</i> as a housekeeping gene (n = 6 mouse at each time-point). …”

Time-course of changes induced on NCAM and SYN synaptic patterns and levels by glutamate exposure. by María Fernanda Podestá (639243)

“…<p>Hippocampal neurons in culture (DIV 12–13) were briefly exposed to 5 µM glutamate and evaluated 1, 3, 6 and 12 h later. …”

Effect of CoQ10 on blood glucose levels and serum levels of resistin, TNF-α, and omentin. by Yousif Jameel Jbrael (17797560)

Effect of CoQ10 on serum levels of LPPLA2, troponin, and creatinine kinase-MB. by Yousif Jameel Jbrael (17797560)

Summary of subgroup analysis results. by Junyin Pan (20700411)

Subjects:

Original study data. by Junyin Pan (20700411)

Subjects: