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point decrease » point increase (Expand Search)
fold decrease » fold increase (Expand Search), fold increased (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
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Magnification X2 of Fig 4A.
Published 2024“…<i>intracellularis</i> bacterial load peaks at 5 dpi. The induction of pro-inflammatory cytokines expression is consistent with the decreased viability of <i>L</i>. …”
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9164
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Critical roles of Thy28 associated with the <i>Pax5</i> 1A promoter in <i>Pax5</i> expression.
Published 2015“…<b>(C)</b> Interaction of Thy28 with the <i>Pax5</i> 1A promoter. The primer positions for real-time PCR are shown (upper panel). …”
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9168
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9169
Table5_Potential Target Analysis of Triptolide Based on Transcriptome-Wide m6A Methylome in Rheumatoid Arthritis.xlsx
Published 2022“…Molecular docking and in vitro experiment suggested that TP and IGF2BP3 had a high binding affinity and TP could decrease the mRNA expression of IGF2BP3 in PBMCs and MH7A.This research established a transcriptional map of m<sup>6</sup>A in RA PBMCs and displayed the hidden association between RNA methylation alterations and associated genes in RA. …”
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9170
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9171
Epigenetic Alterations Affecting Transcription Factors and Signaling Pathways in Stromal Cells of Endometriosis
Published 2017“…Genes found to have DM included examples encoding transporters (<i>SLC22A23</i>), signaling components (<i>BDNF</i>, <i>DAPK1</i>, <i>ROR1</i>, and <i>WNT5A</i>) and transcription factors (<i>GATA</i> family, <i>HAND2</i>, <i>HOXA</i> cluster, <i>NR5A1</i>, <i>OSR2</i>, <i>TBX3</i>). …”
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9172
Table5_Identification of a novel Scn3b mutation in a Chinese Brugada syndrome pedigree: implications for Nav1.5 electrophysiological properties and intracellular distribution of Na...
Published 2024“…Confocal imaging and Western blot analysis demonstrated decreased plasma membrane localization of SCN3B and SCN5A in the P87l group. …”
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9174
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9175
Discovery and Development of <i>N</i>‑[4-(1-Cyclobutylpiperidin-4-yloxy)phenyl]-2-(morpholin-4-yl)acetamide Dihydrochloride (SUVN-G3031): A Novel, Potent, Selective, and Orally Act...
Published 2019“…A series of chemical optimizations guided by in vitro affinity at a histamine H<sub>3</sub> receptor (H<sub>3</sub>R), physicochemical properties, and pharmacokinetics in rats resulted in identification of <i>N</i>-[4-(1-cyclobutyl-piperidin-4-yloxy)phenyl]-2-(morpholin-4-yl)acetamide dihydrochloride (<b>17v</b>, SUVN-G3031) as a clinical candidate. …”
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9177
Transcriptional repression of synapse-related genes and a decrease in spine density by AAV-hGATA1 and AAV-hGATA2 in DG of the rat hippocampus.
Published 2014“…(h) Density of dendritic spines (arrowheads) was significantly decreased in AAV-hGATA1- and AAV-hGATA2-injected rats compared with AAV-ctl-injected rats (a main effect of virus, <i>F</i><sub>2,13</sub> = 12.9, <i>P</i><0.0001; AAV-hGATA1: <i>F</i><sub>1,10</sub> = 21.15, <i>P</i> = 0.0009; AAV-hGATA2: <i>F</i><sub>1,7</sub> = 5.63, <i>P</i> = 0.04). …”
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Top 5 templates of CNN1 isoform 2 by PHYRE2 tool.
Published 2023“…Further, molecular docking experimentation of CNN1 showed the significant interactions at S102, L105, A106, K123, Y124 with five selected PTB-drugs, Allylestrenol (-7.56 kcal/mol), Hydroxyprogesterone caproate (-8.19 kcal/mol), Retosiban (-9.43 kcal/mol), Ritodrine (-7.39 kcal/mol) and Terbutaline (-6.87 kcal/mol). …”
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Amino acid metabolic pathways are influenced by the NC1 POM cycle over expression.
Published 2025“…Metabolites displaying an increase (FC > 1.5, <i><i>p</i> </i>< 0.05) in the NC1 strain are displayed in red. …”
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