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101
Cardiovascular autonomic neuropathy is associated with increased glycemic variability driven by hyperglycemia rather than hypoglycemia in patients with diabetes
Published 2023“…ResultsOf the 40 participants (20 T1DM and 20 T2DM) (aged 40.70 ± 13.73 years, diabetes duration 14.43 ± 7.35 years, HbA1c 8.85 ± 1.70%), 23 (57.5%) had CAN. Despite a lower coefficient of variation (CV) (31.26 ± 11.87 vs. 40.33 ± 11.03, P = 0.018), they had a higher CONGA (8.42 ± 2.58 vs. 6.68 ± 1.88, P = 0.024) with a lower median LBGI (1.60 (range: 0.20–3.50) vs. 4.90 (range: 3.20–7.40), P = 0.010) and percentage median time spent in hypoglycemia (4 (range:4–13) vs. 1 (range:0–5), P = 0.008), compared to those without CAN. …”
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Cardiovascular autonomic neuropathy is associated with increased glycemic variability driven by hyperglycemia rather than hypoglycemia in patients with diabetes
Published 2023“…</p><h3>Results</h3><p dir="ltr">Of the 40 participants (20 T1DM and 20 T2DM) (aged 40.70 ± 13.73 years, diabetes duration 14.43 ± 7.35 years, HbA1c 8.85 ± 1.70%), 23 (57.5%) had CAN. Despite a lower coefficient of variation (CV) (31.26 ± 11.87 vs. 40.33 ± 11.03, P = 0.018), they had a higher CONGA (8.42 ± 2.58 vs. 6.68 ± 1.88, P = 0.024) with a lower median LBGI (1.60 (range: 0.20–3.50) vs. 4.90 (range: 3.20–7.40), P = 0.010) and percentage median time spent in hypoglycemia (4 (range:4–13) vs. 1 (range:0–5), P = 0.008), compared to those without CAN. …”
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A Numerical Study of Heat Transfer and Fluid Flow in a Channel with an Array of Pin Fins in Aligned and Staggered Configurations
Published 2018“…The dimensionless spacing, S*, defined as the ratio of the gap between the fin walls to the fin diameter, is varied between a value of 0.5 and 1. Nine different approaching velocities are considered in this study which resulted in Reynolds number values ranging between 5 and 160. …”
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Wales’ tourists not a burden for local healthcare
Published 2016“…</p><p>Instead, they found that Welsh residents were responsible for the vast majority of unintentional injury presentations to the emergency department. They also found a decrease in non-resident presentations between 2006 and 2014, the data range that was studied.…”
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Elevated Adipsin and Reduced C5a Levels in the Maternal Serum and Follicular Fluid During Implantation Are Associated With Successful Pregnancy in Obese Women
Published 2022“…Higher numbers of top-quality embryos were associated with increased levels of C3, properdin, C1q, factors H and B, C4, and adipsin, but with reduced C2 and C5a levels (p ≤ 0.01).…”
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Neither Neoadjuvant nor Adjuvant Therapy Increases Survival After Biliary Tract Cancer Resection with Wide Negative Margins
Published 2012“…Immediate resection increased median survival from 42.3 to 53.5 months (p = 0.01). …”
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Age, Disease Severity and Ethnicity Influence Humoral Responses in a Multi-Ethnic COVID-19 Cohort
Published 2021“…Despite large numbers of reported seroprevalence studies, there remains a limited understanding of how the magnitude and epitope utilization of the humoral immune response to SARS-CoV-2 viral anti-gens varies within populations following natural infection. …”
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5G User Equipment Phased Array Antenna Architecture for Millimeter Wave Beamforming Applications
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An Auction-Based Scheduling Approach for Minimizing Latency in Fog Computing Using 5G Infrastructure
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From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease
Published 2025“…</p><h2 dir="ltr">Other Information</h2><p dir="ltr">Published in: Metabolic Brain Disease<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s11011-025-01700-z" target="_blank">https://dx.doi.org/10.1007/s11011-025-01700-z</a></p>…”
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Effect of Reaction Pressure and Carrier Gas on Toluene Disproportionation over Molybdenum-ZSM-5 Catalyst.
Published 2020“…This study was aimed at evaluating the effects of reaction pressure and temp. on toluene disproportionation using a ZSM-5-based catalyst impregnated with molybdenum. …”
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RHO A versus RHO C. (c2014)
Published 2016“…The Rho Protein has subtypes designated as RhoA, RhoB, RhoC, RhoD, RhoE, and RhoH genes. In this study we aim to look at the role both Rho A and Rho C play in protrusion formation where we found that upon RhoA knockdown protrusions are no longer formed, using 2D time lapse microscopy that shows the depletion of RhoA and RhoC leads to the decrease in 2D motility, RhoA knockdown decreases adhesion of cells in contrast RhoC knockdown increases adhesion of astrocytoma, and FRET based biosensors. …”
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Coevolving residues distant from the ligand binding site are involved in GAF domain function
Published 2025“…Here, we combine computational and experimental approaches to demonstrate that two highly coevolving residues, L267 and F295, distant from the ligand binding site, play a critical role in GAF domain allostery. Statistical Coupling Analysis (SCA) of GAF domain sequences identified these residues, and molecular dynamics (MD) simulations of both apo and holo forms of wild-type and mutant (L267A, F295A) PDE5 GAFa domains revealed significant changes in structural dynamics and cGMP interaction. …”
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A potential therapeutic agent for sickle cell anaemia
Published 2016“…They also found increased levels of ROS that were associated with decreased levels of antioxidant enzymes and their co-factors.…”
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Carotid artery revascularization through a radiated field
Published 2003“…In a prospective study, late (>70%) carotid artery stenosis was found in 11.7% of 240 patients who had undergone cervical irradiation.6 The chronic effects of radiation therapy lead to decreased vascularity and increased fibrosis, which in turn lead to risk for tissue necrosis, infection, and ulceration. …”
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Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss
Published 2018“…Significant decreases in SLC7A8 transport activity was detected for patient’s variants (p.Val302Ile, p.Arg418His, p.Thr402Met and p.Val460Glu) further supporting a causative role for SLC7A8 in ARHL. …”
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The promise of tirzepatide: A narrative review of metabolic benefits
Published 2025“…Tirzepatide administration for 72 weeks elicited significant weight reduction ranging from 5 % to 20.9 % across different trials in a dose-dependent manner. …”
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