Validation of Polygenic Risk Scores for Coronary Heart Disease in a Middle Eastern Cohort Using Whole Genome Sequencing by Mohamad Saad (214545)

“…Whole genome sequencing at 30× coverage was performed in 1067 coronary heart disease cases (mean age=59 years; 70.3% males) and 6170 controls (mean age=40 years; 43.5% males).</p><h3>Results</h3><p dir="ltr">The majority of PRSs performed well; odds ratio (OR) per 1 SD increase (OR1sd) was highest for PGS000337 (OR1sd=1.81, 95% CI [1.66–1.98], <i>P</i>=3.07×10−41). …”

Managing International NGO Projects - Context, cultural competence and its impact on performance (A Case study from Kenya) by Dale, Jorunn Marie

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Factors associated with baseline smoking self-efficacy among male Qatari residents enrolled in a quit smoking study by Mohammed Al Thani (7487684)

“…Results showed that after controlling for relevant variables, number of cigarettes smoked (β^ = -0.22; 95% CI: -0.37, -0.06), having at least one quit attempt in the past year (β^ = 2.30; 95% CI: 0.27, 4.35), and reporting a complete home smoking ban (β^ = 3.13; 95% CI: 0.56, 5.70) were significantly associated with higher self-efficacy to quit smoking. …”

Verum- versus Sham-Acupuncture on Alzheimer’s Disease (AD) in Animal Models: A Preclinical Systematic Review and Meta-Analysis by Fei-Yi Zhao (10887219)

“…Alzheimer’s disease (AD) is a common health condition affecting senile people and leads to severe cognitive dysfunctions. …”

Assessing the risk of angiotensin receptor blockers on major cardiovascular events: a systematic review and meta-analysis of randomized controlled trials by Yara Wanas (8744844)

“…</p><h2>Other Information</h2><p dir="ltr">Published in: BMC Cardiovascular Disorders<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1186/s12872-020-01466-5" target="_blank">http://dx.doi.org/10.1186/s12872-020-01466-5</a></p>…”

A new One Health Framework in Qatar for future emerging and re-emerging zoonotic diseases preparedness and response by Devendra, Bansal

“…One Health is increasingly recognized as an optimal approach to address the global risk of health threats originating at the human, animal, and ecosystem interface, and their impact. …”
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Prostate cancer burden in South Asia: A systematic analysis of global burden of disease data (1990–2021) by Vijay Kumar (377076)

Wide Range Voltage Scaling Converter With Extended Duty and Low Voltage Stress for a DC Microgrid Applications by Md Samiullah (16888767)

“…In addition, the closed-loop operation of the converter is validated by its ability to maintain a regulated 400 V dc bus voltage, despite variations in the input voltage.…”

Comfort Assessment of a Fully/Semi-enclosed Courtyard: Case Study of Bahrain Low Rise Villa Housing Model by Al Awadhi, Maryam Hasan

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Chemopreventive effects of wild carrot oil against 7,12-dimethyl benz(a)anthracene-induced squamous cell carcinoma in mice by Abu Zeinab, Rami

“…The extract was administered to animals via gavage (0.02 mL of 100% oil), intraperitoneal (0.3 mL of 2% oil), and topical (0.2 mL of 5, 50, and 100% oil) routes for 20 weeks. Tumor appearance, incidence, yield, and volume were compared with those of a non-treated control group. …”
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Risk factors for early death due to recurrence after liver resection for hepatocellular carcinoma: Results of a multicenter study by Abdalla, Eddie

“…On multivariateanalysis, tumor size greater than 5 cm (P < 0.02; odds ratio, 3.0), multiple tumors(P < 0.01; odds ratio, 3.3), and greater than 5 mitoses per 10 high-power fields(P < 0.03; odds ratio, 3) were associated with increased risk of early death due torecurrence.Conclusions: These findings enable identification of patients with HCC who are athigh risk for early death due to recurrence following potentially curative resection whomight be candidates for adjuvant therapy trials.…”
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Unravelling the predictors of late cancer presentation and diagnosis in Jordan: a cross-sectional study of patients with lung and colorectal cancers by Damsees, Rana

“…The results of backward multivariate logistic regression analyses showed that female gender and not seeking a medical advice when feeling ill combined was associated with an almost three times increased likelihood of reporting a late presentation with cancer (adjusted OR 2.97, 95% CI 1.19 to 7.43). …”
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Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells By Peter Nasr A thesis by Nasr, Peter

“…Positive Annexin V staining, as well as DNA fragmentation, confirm an increase in apoptotic cell death by upregulating the expression of pro-apoptotic proteins which control both intrinsic and extrinsic pathways of apoptosis. …”
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Benthic development on large-scale engineered reefs: a comparison of communities among breakwaters of different age and natural reefs by Burt, John

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Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 by Stein Emil, Vollset

“…FindingsIn the reference scenario forecast, global and super-regional life expectancy increased from 2022 to 2050, but improvement was at a slower pace than in the three decades preceding the COVID-19 pandemic (beginning in 2020). …”
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Overheating risk of a single-family detached house built at different ages under current and future climate in Canada by Mutasim Baba, Fuad

“…This paper confirms that the Canadian buildings have the overheating risk over the hot summer experienced over the past a few years and the risk will be increased in the future. …”
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Social determinants of depression among mid-to-older aged Australians: A prospective study of the effects of neighbourhood disadvantage and crime by Vincent, Learnihan

“…A prospective sample of residentially stable persons who reported depression at two years (n =3120) and five years (n=2249) post-follow-up was developed. …”
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Cost-Benefit Analysis of Antimicrobial Stewardship Program Maturity in Adult Surgical Ward Settings: A Retrospective Study in Qatar by Nurhan Elshafey (18472387)

Perinatal factors impacting echocardiographic left ventricular measurement in small for gestational age infants: a prospective cohort study by Ibrahim Elmakaty (14614270)

“…Furthermore, SGA infants were more likely to be born to nulliparous women (63.16% vs. 38.16%; p<0.001), with lower body mass index (BMI) (29.8 vs. 31.7; p=0.004), a lower prevalence of gestational maternal diabetes (GDM) (14.9 % vs. 35.5%; p<0.001), and a higher prevalence of preeclampsia (18.4 % vs. 6.52%; p<0.001). …”

Design of an integrated system that combines the steam gasification of plastic waste and a solid oxide fuel cell for sustainable power generation by Khaled Abouemara (17823416)

“…Optimal conditions are met at gasifier temperature of 973 K, steam/feed ratio of 1.5, and CaO/feed ratio of 1. Moreover, using H₂ flow rates to assess SOFC performance reveal increasing activation and ohmic losses (0.04 to 0.09 V and 0 to 0.28 V) with a temperature increase (973–1473 K), while concentration losses decreased (0–0.10 V). …”