Reply to Comments by Kakkar and Dahiya حسب Chahine, Elias B.

"…Initial reports describing the use of bedaquiline in patients with MDR-TB and extensively drug-resistant TB are promising.3,4 Fortunately, the World Health Organization (WHO) has recently issued an interim policy guidance recommending that bedaquiline may be added to a WHO-recommended regimen in adult patients with MDR-TB when an effective regimen containing 4 second-line drugs in addition to pyrazinamide cannot be designed, and when there is documented evidence of resistance to any fluoroquinolone in addition to multidrug resistance.5 Similarly, the Centers for Disease Control and Prevention (CDC) has also issued provisional guidelines recommending that bedaquiline may be used for 24 weeks in adults with laboratory-confirmed pulmonary MDR-TB when an effective regimen cannot otherwise be provided; on a case-by-case basis in children, persons with HIV, pregnant women, persons with extrapulmonary MDR-TB, and patients with comorbidties when effective regimen cannot otherwise be provided; and on a case-by-case basis for durations longer than 24 weeks when an effective regimen cannot be provided.6 Both WHO and CDC emphasize the need for careful monitoring of patients on bedaquiline therapy for safety concerns.5,6 Until further data become available, the authors believe that patients who meet eligible criteria according to current guidelines may benefit from bedaquiline therapy with careful monitoring for potential side effects and drug interactions.…"
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Patterns of pain medication use in older individuals with cardiovascular disease حسب Kabbara, Wissam K.

"…Background: Pain is common in older adults and clinicians are often faced by many challenges when selecting appropriate treatment due to age-related changes in pharmacokinetics, pharmacodynamics, increased comorbidities, and polypharmacy. Methods: This study assessed the patterns of pain medications used at home among older adults admitted to the cardiology service in a tertiary care teaching center in the US from March to May 2016. …"
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Sciatic nerve stimulation activates the retrotrapezoid nucleus in anesthetized rats حسب Kanbar, Roy

"…Sciatic nerve stimulation (SNstim, 1 ms, 0.5Hz) slightly increased blood pressure (6.6 ± 1.6 mmHg) and heart rate and, at low eeCO2 (<5.5%), entrained PND. …"
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Recent advances in the treatment and outcome of locally advanced rectal cancer حسب Abdalla, Eddie

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Meal pattern of male rats maintained on histidine-, leucine-, or tyrosine-supplemented diet. حسب Bassil, Maya S.

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The Sustainability (Environmental and Economical) impact of upgrading Bahrain building regulations for affordable housing units: Case study in Bahrain حسب Al-Saffar, May

"…However, fast growth of cities and construction development will form a pressure on the energy demand and consequently on the environment and will contribute in the global warming due to the increase of carbon footprint. …"
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Pattern of Postoperative Mortality After Esophageal Cancer Resection According to Center Volume حسب Markar, Sheraz

"…Results The 30-day and in-hospital POM rates were 5.0 and 7.3 %, respectively. Pulmonary complications were the most common, affecting 38.1 % of patients, followed by surgical site infection (15.5 %), cardiovascular complications (11.2 %), and anastomotic leak (10.2 %). …"
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Teaching Benign Paroxysmal Positional Vertigo to Emergency Medicine Residents by Using Gagne’s Nine Steps of Instructional Design حسب Khalid Bashir (9300293)

"…The median score before the course for the DH test was 2 (1.7– 3.0) and improved to 5(4.0– 5.0). Similarly, CR’s median score improved from 2 (1.0– 2.3) to 5 (4.7– 5.0). …"

Epidemiology of gonorrhoea: systematic review, meta-analyses, and meta-regressions, World Health Organization European Region, 1949 to 2021 حسب Omar Chidiac (3158871)

"…Among men who have sex with men, pooled prevalence was 0.9% (95% CI: 0.5–1.4%), 5.6% (95% CI: 3.6–8.1%), and 3.8% (95% CI: 2.5–5.4%), respectively, for current urogenital, anorectal or oropharyngeal infection. …"

Adsorptive Removal of Dyes from Aqueous Solutions Using Metal Organic Frameworks (MOFs) حسب Karami, Abdollah

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Wild carrot oil extract is selectively cytotoxic to human acute myeloid leukemia cells حسب Tawil, Mirna

"…Analysis of mechanism of cell death showed an increase in cells positive for annexinV and for active caspases, indicating that DCOE induces apoptotic cell death in AML. …"
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Education in Tanzania حسب Jane Manyama (22501084)

Exploring environmental, social, and governance and bank performance in the Gulf Cooperation Council region حسب Jaywant Michael (17541642)

"…</p><h2>Other Information</h2><p dir="ltr">Published in: Corporate Law and Governance Review<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.22495/clgrv5i2sip6" target="_blank">https://dx.doi.org/10.22495/clgrv5i2sip6</a></p>…"

Pharmacological interventions targeting β-adrenoceptors in colorectal cancer: an evolving paradigm حسب Aya Ghosn (22997230)

"…</p><h2 dir="ltr">Other Information</h2><p dir="ltr">Published in: Inflammopharmacology<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s10787-025-01925-5" target="_blank">https://dx.doi.org/10.1007/s10787-025-01925-5</a></p>…"

Postprandial hyperaminoacidaemia overcomes insulin resistance of protein anabolism in men with type 2 diabetes حسب Bassil, M.

"…Hyper-2 results were compared with those of diabetic men whose plasma glucose was lowered to 5.5 mmol/l and fasting aminoacidaemia maintained during the hyperinsulinaemic clamp (Hyper-1). …"
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Spatiotemporal Variation in Mangrove Chlorophyll Concentration using Remote Sensing Technique حسب Ali Mohamed (3546578)

Pravastatin plus L-arginine prevents adverse pregnancy outcomes in women with uteroplacental vascular dysfunction حسب Aleksandar Jurisic (17052408)

"…</p><p dir="ltr">10 pregnant women with a poor obstetric history that developed uteroplacental dysfunction (UtA pulsatility index (PI) above the 95th percentile and notching) at 20.5 weeks IQR [17.7–22] gave consent to be treated daily with pravastatin (40 mg) and L-arginine (1.5 g) to improve placental blood flow and pregnancy outcomes. 5 women remained untreated after diagnosis at 21 weeks [20−22] (control group). …"

Water Footprint Assessment and Virtual Water Trade in the Globally Most Water-Stressed Country, Qatar حسب Nayla Higazy (17679453)

Expectations of emergency patients regarding triage system knowledge upon arrival: an interpretive study حسب Mohammad Minwer Alnaeem (19143733)

"…</p><h2>Other Information</h2><p dir="ltr">Published in: Irish Journal of Medical Science (1971 -)<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s11845-024-03706-5" target="_blank">https://dx.doi.org/10.1007/s11845-024-03706-5</a></p>…"

Molecular epidemiology of clinical filamentous fungi in Qatar beyond Aspergillus and Fusarium with notes on the rare species حسب Husam Salah (14723577)

"…<p>Due to an increasing number of patients at risk (i.e., those with a highly compromised immune system and/or receiving aggressive chemotherapy treatment), invasive fungal infections (IFI) are increasingly being reported and associated with high mortality rates. …"