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Technical assessment of different extraction methods and transcriptome profiling of RNA isolated from small volumes of blood
Published 2023“…Such non-invasive sampling of small volumes of blood offers practical advantages. The quality of gene expression data is strictly dependent on the steps used for the sample collection, extraction, preparation and sequencing. …”
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Long-Chain Acyl-CoA Synthetase 1 Role in Sepsis and Immunity: Perspectives From a Parallel Review of Public Transcriptome Datasets and of the Literature
Published 2019“…Finally, while ACSL1 expression was induced in blood in vitro by a wide range of pathogen-derived factors as well as TNF, induction of ACSL4 appeared restricted to flagellated bacteria and pathogen-derived TLR5 agonists and IFNG. …”
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163
Thrombotic and Hypercoagulability Complications of COVID-19: An Update
Published 2021“…<p dir="ltr">The current COVID-19 pandemic emerged in December 2019, in China, affecting millions of people worldwide. COVID-19 is mainly a disease of the respiratory system, yet systematic complications have also been reported among SARS-CoV-2 infected patients. …”
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Dietary Trichosporon mycotoxinivoron modulates ochratoxin-A induced altered performance, hepatic and renal antioxidant capacity and tissue injury in broiler chickens
Published 2021“…<p dir="ltr">Ochratoxin A (OTA), an important fungal metabolite in foods and feeds has been shown to induce oxidative stress and cellular injuries to human and animal subjects. …”
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Immune thrombocytopenia relapse post covid-19 vaccine in young male patient
Published 2021“…<p dir="ltr">Immune thrombocytopenic purpura (ITP) is a blood disorder in which antibodies coating platelets cause platelets destruction in the spleen with resultant low platelets count and an increased tendency for bleeding. …”
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166
Regulative Loop between β-catenin and Protein Tyrosine Receptor Type γ in Chronic Myeloid Leukemia
Published 2020“…Furthermore, we demonstrated that the increased expression of β-catenin in PTPRG-negative CML cell lines correlates with DNA (cytosine-5)-methyl transferase 1 (DNMT1) over-expression, which is responsible for PTPRG promoter hypermethylation, while its inhibition or down-regulation correlates with PTPRG re-expression. …”
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A Study on Impact of Change in Contractor’s Project Organization Structure on Project Performance
Published 2016“…Moreover, contractor’s senior managers play an essential and a vital role in establishing and management the project organization structure, ID # 2013122149 Dissertation MSc.CM P a g e | 4 consequently any unnecessary changes and slow or inadequate response to the project organization structure change will lead to negative impact on the project performance like increase the project activity reworks; weak communication between project team; increase of material wastages; time delay and cost overrun. …”
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169
Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis
Published 2025“…Ex vivo incubation of LAT2KO muscle with rapamycin recovered proteolysis function, demonstrating a mTORC1‐dependent pathway. Decreased proteolysis in LAT2KO animals was associated with increased mTORC1 translocation to the lysosome (mTORC1‐Lamp1 colocalization in fasted LAT2KO muscles was 1.23‐fold, <i>p</i> < 0.0001). …”
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Akkermansia, a Possible Microbial Marker for Poor Glycemic Control in Qataris Children Consuming Arabic Diet—A Pilot Study on Pediatric T1DM in Qatar
Published 2021“…Moreover, genus <i>Akkermansia</i> was higher in the subjects with poor glycemic control (HbA1c > 7.5%). When we classified the subjects based on dietary patterns and nationality, <i>Akkermansia</i> was significantly enriched in Qataris subjects without the CSII therapy consuming Arabic diet than expatriates living in Qatar and eating a Western/mixed diet. …”
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Platelet Protein-Related Abnormalities in Response to Acute Hypoglycemia in Type 2 Diabetes
Published 2021“…</p><h3>Methods </h3><p dir="ltr">A case-control study of T2D (n=33) and control subjects (n=30) who underwent a hyperinsulinemic clamp to induce normoglycemia in T2D subjects: T2D: baseline glucose 7.5 ± 0.3mmol/l (135.1 ± 5.4mg/dl), reduced to 4.5 ± 0.07mmol/l (81 ± 1.2mg/dl) with 1-hour clamp; Controls: maintained at 5.1 ± 0.1mmol/l (91.9 ± 1.8mg/dl). …”
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Biomarkers of COVID-19 severity may not serve patients with polycystic ovary syndrome
Published 2021“…Whilst the comparison with absolute disease-free normality is relevant, an increasing proportion of the population have insulin resistant states with associated metabolic conditions; an example of such a metabolic condition is polycystic ovary syndrome (PCOS) where it has been shown that protein expression patterns may differ compared to those without PCOS [3]. …”
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Experimental investigations on the performance of a thermo-mechanical refrigeration system utilizing ultra-low temperature waste heat sources
Published 2023“…At a heat source temperature of 85 °C, a condenser water temperature of 15 °C, and an evaporator water temperature of 33 °C, the energy efficiency of the ORC and COP of the VCC are increased to 9.85 % and 3.99, respectively. …”
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Layered homologous compounds (ZnO)<sub><em>k</em></sub>In<sub>2</sub>O<sub>3</sub> (<i>k</i> = 3, 5, and 7) as novel photocatalysts for visible-light-driven photocatalytic degradat...
Published 2024“…<p dir="ltr">Homologous compounds (ZnO)<sub><em>k</em></sub>In<sub>2</sub>O<sub>3</sub> (hereafter IZO-<i>k</i>, where <i>k</i> = 3, 5, and 7) consist of a layered structure that features optically active and electrically conductive segments together. …”
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175
MicroRNA Expression Profiling on Paired Primary and Lymph Node Metastatic Breast Cancer Revealed Distinct microRNA Profile Associated With LNM
Published 2020“…The expression of 14 miRNAs (Up: hsa-miR-155-5p, hsa-miR-150-5p, hsa-miR-146a-5p, hsa-miR-142-5p and down: hsa-miR-200a-3p, hsa-miR-200b-3p, hsa-miR-200c-3p, hsa-miR-205-5p, hsa-miR-210-3p, hsa-miR-214-3p, hsa-miR-141-3p, hsa-miR-127-3p, hsa-miR-125a-5p, and hsa-let-7c-5p) was subsequently validated in a second cohort of 32 breast and 32 matched LNM tumor tissues. …”
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176
Association Between Periodontitis and COVID-19
Published 2024“…</p><h3>Recent Findings</h3><p dir="ltr">A growing body of evidence suggests that periodontitis could increase the risk of COVID-19 infection and its complications. …”
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177
Comparative Genomic Mapping Implicates LRRK2 for Intellectual Disability and Autism at 12q12, and HDHD1, as Well as PNPLA4, for X-Linked Intellectual Disability at Xp22.31
Published 2020“…<p dir="ltr">We report a genomic and phenotypic delineation for two chromosome regions with candidate genes for syndromic intellectual disability at 12q12 and Xp22.31, segregating independently in one family with four affected members. …”
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The relationship of soluble neuropilin-1 to severe COVID-19 risk factors in polycystic ovary syndrome
Published 2021“…SARS-CoV-2 uses the viral spike protein for cell entry, cleaving the protein that then attaches to NRP1 [5]. …”
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Tolfenamic Acid Derivatives: A New Class of Transcriptional Modulators with Potential Therapeutic Applications for Alzheimer’s Disease and Related Disorders
Published 2023“…More importantly, the proteome of treated cells displayed ~75% of the downregulated products as SP1 targets. Specific levels of SP1-driven genes and AD biomarkers such as amyloid precursor protein (APP) and Tau proteins were also decreased as part of this targeted systemic response. …”
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State-of-the-Art Review on Recent Advancements on Lateral Control of Autonomous Vehicles
Published 2022“…</p><h2>Other Information</h2><p>Published in: IEEE Access<br>License: <a href="https://creativecommons.org/licenses/by/4.0/legalcode" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1109/access.2022.3217213" target="_blank">https://dx.doi.org/10.1109/access.2022.3217213</a></p>…”