A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T ce... حسب Abou-Ghazal, Mohamed

"…Results: WP1066 achieved an IC50 of 1.6, 2.3, and 1.5 μmol/L against melanoma cell line A375, B16, and B16EGFRvIII, respectively. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021 حسب Kanyin Liane, Ong

"…However, all evidence indicates that diabetes prevalence is increasing worldwide, primarily due to a rise in obesity caused by multiple factors. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Global, regional, and national prevalence of adult overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021 حسب Marie, Ng

"…While China, India, and the USA will continue to constitute a large proportion of the global population with overweight and obesity, the number in the sub-Saharan Africa super-region is forecasted to increase by 254·8% (234·4–269·5). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Unveiling the Nexus Between Land Use, Land Surface Temperature, and Carbon Footprint: A Multi-Scale Analysis of Building Energy Consumption in Arid Urban Areas حسب Ammar Abulibdeh (15785928)

"…</p><h2>Other Information</h2><p dir="ltr">Published in: Earth Systems and Environment<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s41748-024-00550-6" target="_blank">https://dx.doi.org/10.1007/s41748-024-00550-6</a></p>…"

Co-production of high density biomass and high-value compounds via two-stage cultivation of Chlorella vulgaris using light intensity and a combination of salt stressors حسب Eman A. El-fayoumy (17788952)

"…Cultivation of C. vulgaris in a medium containing 7.5 g L⁻¹ NaCl/ 7.5 g L⁻¹ CaCl₂ had remarkably increased the lipid content (31.15 ± 1.18%) and lipid productivity (14.55 ± 1.48 mg L⁻¹ d⁻¹). …"

Measuring routine childhood vaccination coverage in 204 countries and territories, 1980–2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1 حسب Natalie C Galles (9715361)

"…</p><p><br></p><h3>Findings</h3><p dir="ltr">By 2019, global coverage of third-dose DTP (DTP3; 81·6% [95% uncertainty interval 80·4–82·7]) more than doubled from levels estimated in 1980 (39·9% [37·5–42·1]), as did global coverage of the first-dose measles-containing vaccine (MCV1; from 38·5% [35·4–41·3] in 1980 to 83·6% [82·3–84·8] in 2019). …"

A urokinase-activated recombinant diphtheria toxin targeting the granulocyte-macrophage colony-stimulating factor receptor is selectively cytotoxic to human acute myeloid leukemia... حسب Abi-Habib, Ralph J.

"…The activity of this toxin was then tested on a larger group of 13 human AML cell lines; 5 of the 13 cell lines were sensitive to DTU2GMCSF. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Potential distribution of a noxious weed (<i>Solanum viarum</i> Du-nal), current status, and future invasion risk based on MaxEnt modeling حسب Muhammad Waheed (11719398)

"…Under climate change regimes, the highly suitable area for <i>S. viarum</i> increases by 2–9% under two Representative Concentration Pathways (RCP 4.5 and RCP 8.5). …"

A novel design for battery cooling based on highly thermally conductive phase change composites encapsulated by 3D printed polyethylene/boron nitride layer حسب Safna Nishad (16932474)

"…A battery cooling pack (BCP), designed as a hollow cylindrical structure, effectively manages individual lithium-ion batteries' thermal performance without any PW leakage. …"

Remediation of boron, lithium, and molybdenum by date pits modified with graphene oxide and cellulose nanocrystals: Mechanistic studies حسب Dana A. Da'na (17019120)

"…<p dir="ltr">This work aimed to modify date pits (DP), an agricultural waste product, with graphene oxide (GO) and cellulose nanocrystals (CNC) to develop a novel, environmentally friendly adsorbent referred to as GO-CNC@DP. …"

Global, regional, and national burden of respiratory tract cancers and associated risk factors from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019 حسب Hedyeh Ebrahimi (7321358)

"…Global age-standardised incidence rates of tracheal, bronchus, and lung cancer decreased by 7·4% (−16·8 to 1·6) and age-standardised incidence rates of larynx cancer decreased by 3·0% (−10·5 to 5·0) in males over the past decade; however, during the same period, age-standardised incidence rates in females increased by 0·9% (−8·2 to 10·2) for tracheal, bronchus, and lung cancer and decreased by 0·5% (−8·4 to 8·1) for larynx cancer. …"

Use of Animal Models for Investigating Cardioprotective Roles of SGLT2 Inhibitors حسب Najlaa A. Al Thani (17788493)

"…</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Cardiovascular Translational Research<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s12265-023-10379-5" target="_blank">https://dx.doi.org/10.1007/s12265-023-10379-5</a></p>…"

Forecasting the effects of smoking prevalence scenarios on years of life lost and life expectancy from 2022 to 2050: a systematic analysis for the Global Burden of Disease Study 20... حسب Dana, Bryazka

"…Under our Elimination-2023 scenario, we forecast 2·04 billion (95% UI 1·90–2·21) fewer cumulative YLLs by 2050 compared with the reference scenario, and life expectancy at birth would increase to 77·6 years (95% UI 75·1–79·6) among males and 81·0 years (78·5–83·1) among females. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Cadmium-induced endothelial dysfunction mediated by asymmetric dimethylarginine حسب Hamda A. Al-Naemi (14151675)

"…</p><h2>Other Information</h2><p dir="ltr">Published in: Environmental Science and Pollution Research<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1007/s11356-020-08116-5" target="_blank">http://dx.doi.org/10.1007/s11356-020-08116-5</a></p>…"

The global, regional, and national burden of oesophageal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global... حسب Farin Kamangar (63964)

"…In 2017, age-standardised incidence was 2·7 times higher, mortality 2·9 times higher, and DALYs 3·0 times higher in males than in females. In 2017, a substantial proportion of oesophageal cancer DALYs were attributable to known risk factors: tobacco smoking (39·0% [35·5–42·2]), alcohol consumption (33·8% [27·3–39·9]), high BMI (19·5% [6·3–36·0]), a diet low in fruits (19·1% [4·2–34·6]), and use of chewing tobacco (7·5% [5·2–9·6]). …"

Efficacy of lower arch leveling, lower incisors’ root resorption, and pain associated with the correction of curve of Spee using different orthodontic archwires: a randomized clini... حسب Yousef H. Nasrawi (14146809)

"…The intervention was randomly allocated using the permuted random block size of 3 with a 1:1:1 allocation ratio. In the three groups, a 5-mm depth reverse COS was placed in the AWs. …"

A Quadratic Non-Isolated High Step-Up Single-Input Dual-Output DC–DC Topology Based on Coupled Inductors with Low Input Current Ripple حسب Vafa Marzang (17347048)

"…The proposed SIDO (or SISO) topology includes two CI, two independent switches, four (three) diodes, and five (four) capacitors. The proposed converter produces high DC output voltages at a low value of duty cycles and low voltage stress across the power MOSFETs. …"

The global, regional, and national burden of colorectal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global B... حسب Saeid Safiri (3713035)

"…Although the overall colorectal cancer age-standardised death rate has been decreasing at the global level, the increasing age-standardised incidence rate in most countries poses a major public health challenge across the world. …"

Global, regional, and national mortality among young people aged 10–24 years, 1950–2019: a systematic analysis for the Global Burden of Disease Study 2019 حسب Joseph L Ward (9715619)

"…Annual percentage decrease in all-cause mortality rate since 1990 in adolescents aged 15–19 years was 1·3% in males and 1·6% in females, almost half that of males aged 1–4 years (2·4%), and around a third less than in females aged 1–4 years (2·5%). …"

Awareness of primary health care physicians about human papilloma virus infection and its vaccination: a cross sectional survey from multiple clinics in Saudi Arabia حسب Almughais, Ebtehaj S.

"…Materials and methods: A self-administered survey was conducted in 2017 at eleven PHC clinics in Saudi Arabia. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل