Prostaglandin E2 regulates the level and stability of cyclooxygenase-2 mRNA through activation of p38 mitogen-activated protein kinase in interleukin-1β-treated human synovial fibr... حسب Faour, Wissam

"…We observed a rapid (5 min), massive (>30-fold), and sustained (>48 h) increase in COX-2 mRNA, protein, and PGE2 release following a recombinant human (rh) IL-1β signal that was inhibited by NS-398, a COX-2 inhibitor, and SB202190, a selective, cell-permeable p38 MAPK inhibitor. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Patients’ Perspectives About Factors Affecting Their Use of Electronic Personal Health Records in England: Qualitative Analysis حسب Alaa Abd-Alrazaq (17430900)

"…A convenience sample was recruited in 4 GPs in West Yorkshire, England. …"

Beauvericin potentiates the activity of pesticides by neutralizing the ATP-binding cassette transporters in arthropods حسب Charbel Al Khoury (13167975)

"…</p><h2>Other Information</h2> <p> Published in: Scientific Reports<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1038/s41598-021-89622-5" target="_blank">http://dx.doi.org/10.1038/s41598-021-89622-5</a></p>…"

10-Day structured initiation protocol from multiple daily injection to hybrid closed-loop system in children and adolescents with type 1 diabetes حسب Goran Petrovski (129836)

"…The mean HbA1c decreased from 8.2 ± 1.4% (66 ± 15.3 mmol/mol) at baseline to 6.7 ± 0.5% (50 ± 5.5 mmol/mol) at the end of the study (p = 0.017). …"

Tranexamic acid for the prevention of blood loss after cesarean section: an updated systematic review and meta-analysis of randomized controlled trials حسب Huzaifa Ahmad Cheema (16328980)

"…</p> <h3>Methods</h3> <p>We used the revised Cochrane “Risk of Bias" tool (RoB 2.0) to assess the quality of included RCTs. RevMan 5.4 was used to conduct all statistical analyses under a random-effects model.…"

National-level and state-level prevalence of overweight and obesity among children, adolescents, and adults in the USA, 1990–2021, and forecasts up to 2050 حسب Marie, Ng

"…For individuals older than 18 years, overweight was defined as having a BMI of 25 kg/m2 to less than 30 kg/m2 and obesity was defined as a BMI of 30 kg/m2 or higher, and for individuals younger than 18 years definitions were based on International Obesity Task Force criteria. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The E3 ubiquitin-protein ligase UHRF1 promotes adipogenesis and limits fibrosis by suppressing GPNMB-mediated TGF-β signaling حسب Muneera Vakayil (12037693)

National-level and state-level prevalence of overweight and obesity among children, adolescents, and adults in the USA, 1990–2021, and forecasts up to 2050 حسب Marie, Ng

"…For individuals older than 18 years, overweight was defined as having a BMI of 25 kg/m2 to less than 30 kg/m2 and obesity was defined as a BMI of 30 kg/m2 or higher, and for individuals younger than 18 years definitions were based on International Obesity Task Force criteria. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the Global Burden of Disease Study حسب Rupert Bourne (603842)

"…Globally, between 1990 and 2020, among adults aged 50 years or older, age-standardised prevalence of blindness decreased by 28·5% (–29·4 to −27·7) and prevalence of mild vision impairment decreased slightly (–0·3%, −0·8 to −0·2), whereas prevalence of moderate and severe vision impairment increased slightly (2·5%, 1·9 to 3·2; insufficient data were available to calculate this statistic for vision impairment from uncorrected presbyopia). …"

Effect of Surgical Margin Status on Survival and Site of Recurrence After Hepatic Resection for Colorectal Metastases حسب Pawlik, Timothy

"…Results: On final pathologic analysis, margin status was positive in 45 patients, and negative by 1 to 4 mm in 129, 5 to 9 mm in 85, and ≥1 cm in 298. At a median follow-up of 29 months, the 1-, 3-, and 5-year actuarial survival rates were 97%, 74%, and 58%; median survival was 74 months. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Lifetime prevalence of mental disorders in Lebanon حسب Dimassi, Hani

"…War exposure increased the risk of first onset of anxiety (odds ratio [OR] 5.92, 95% confidence interval [CI] 2.5–14.1), mood (OR 3.32, 95% CI 2.0–5.6), and impulse control disorders (OR 12.72, 95% CI 4.5–35.7). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Effects of Operating Conditions on Water Absorption Capacity of Superabsorbent Hydrogels حسب Abdelwahab, Noun

احصل على النص الكامل

Programming Effects of Short Prenatal Exposure to Dexamethasone in Sheep حسب Abouantoun, Tamara

"…At 130 days of gestation, dexamethasone administered between 26 to 28 days of gestation (group DF; n8), resulted in an increased expression of angiotensinogen in hypothalamus (in arbitrary units: 2.5 0.3 versus 1.3 0.3 in the saline group [group SF], n10; P0.05). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Role of PDE3 and PDE4 for β-adrenergic control of cAMP and ICa,L in adult rat ventricular myocytes حسب Leroy, Jerome

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The changing face of Qatar حسب Nature Research (16552612)

"…Although Qatar has seen a significant improvement in under-five and maternal mortality rates, and lowest rates of communicable disease and all-cause mortality rates, it has an extremely high prevalence of obesity, and this is continuing to increase. …"

Cost-Effectiveness of Fetal Fibronectin Testing to Predict Preterm Birth in Pregnant Women with Symptoms of Premature Labour حسب Dina Abushanab (10696501)

"…The fFN group had 12% success rate in prolonging delivery at 48 hours following receiving one cycle of atosiban and antenatal corticosteroids compared to 5% with no-fFN group, [risk ratio (RR)= 0.93; 95% CI, 0.85 to 1.01; P = 0.08]. fFN testing was estimated to dominate the no-fFN testing group, at a cost saving of QAR 236,702 (US$ 64,850), with total healthcare costs of QAR 171,623 (US$ 47,020) versus QAR 408,325 (US$ 111,870), respectively. …"

Metal Organic Frameworks Electrodes for Microbial Fuel Cell Applications and Hydrogen Production حسب Al-Murisi, Mohammed Abdullah Taher Mohammed

احصل على النص الكامل

Assessment of resin systems as solution for well integrity challenge in carbonate reservoirs حسب Albertus Retnanto (17269237)

"…Based on the performed experimental tests results, the optimal additive resin for a class G cement slurry is the microbond additive at a concentration of 7.5%. …"

The Kumaraswamy Pareto IV Distribution حسب Tahir, M. H.

احصل على النص الكامل

MRP4 حسب Abi-Gerges, Aniella

"…Application of ISO (1nM) induced a similar increase in cAMP level in WT and MRP4 KO mice (YFP/CFP: 4.4 ± 0.15 in WT vs 4.1 ± 0.44 in KO cells), whereas cAMP signal was greater in MRP4 KO compared to WT mice after PDE inhibition by IBMX (ISO 1nM + IBMX 300µM: 8.1 ± 0.6 in WT vs 11.8 ± 0.62 in KO cells; p<0.01). …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل