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1801
AI-driven cybersecurity framework for software development based on the ANN-ISM paradigm
Published 2025“…<p dir="ltr">With the increasing reliance on software applications, cybersecurity threats have become a critical concern for developers and organizations. …”
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1802
Epigenetic DNA Methylation Signatures Associated With the Severity of Paget’s Disease of Bone
Published 2022“…Additionally, methylation profiles in 11 regions showed Bonferroni-significant association with disease severity including six islands (located in VCL, TBX5, CASZ1, ULBP2, NUDT15 and SQSTM1), two gene bodies (CXCR6 and DENND1A), and 3 promoter regions (RPL27, LINC00301 and VPS29). …”
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1803
Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function
Published 2024“…In cardiac muscle, CaM modulates directly or indirectly the activity of several proteins that play a key role in excitation‐contraction coupling (ECC), such as ryanodine receptor type 2 (RyR2), l‐type Ca<sup>2+</sup> (Ca<sub>v</sub>1.2), sodium (NaV1.5) and potassium (KV7.1) channels. …”
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1804
Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the Global Burden of Disease Study
Published 2020“…Globally, between 1990 and 2020, among adults aged 50 years or older, age-standardised prevalence of blindness decreased by 28·5% (–29·4 to −27·7) and prevalence of mild vision impairment decreased slightly (–0·3%, −0·8 to −0·2), whereas prevalence of moderate and severe vision impairment increased slightly (2·5%, 1·9 to 3·2; insufficient data were available to calculate this statistic for vision impairment from uncorrected presbyopia). …”
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1805
Effect of Surface Treatment of Halloysite Nanotubes (HNTs) on the Kinetics of Epoxy Resin Cure with Amines
Published 2020“…Detailed assessment revealed that autocatalytic reaction degree, m increased at low heating rate from 0.107 for neat epoxy/amine system to 0.908 and 0.24 for epoxy/P-HNT and epoxy/A-HNT nanocomposites, respectively, whereas epoxy/F-HNT system had m value of 0.072 as a signature of dominance of non-catalytic reactions. …”
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1806
Chamber investigation of the formation and transformation of secondary organic aerosol in mixtures of biogenic and anthropogenic volatile organic compounds
Published 2022“…The observed average SOA particle mass yields (the organic particle mass produced for a mass of VOC consumed) in descending order were found for the following systems: α-pinene (32 ± 7 %), α-pinene–o-cresol (28 ± 9 %), α-pinene at 1/2 initial reactivity (21 ± 5 %), α-pinene–isoprene (16 ± 1 %), α-pinene at 1/3 initial reactivity (15 ± 4 %), o-cresol (13 ± 3 %), α-pinene–o-cresol–isoprene (11 ± 4 %), o-cresol at 1/2 initial reactivity (11 ± 3 %), o-cresol–isoprene (6 ± 2 %), and isoprene (0 ± 0 %). …”
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1807
Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts
Published 2020“…In order to investigate the inhibitory mechanisms of these two compounds towards fibril formation, we demonstrated that salvianolic acid B binds predominantly to monomers, while dihydromyricetin binds to oligomeric species and to a lower extent to monomers. Remarkably, these two compounds stabilized the soluble non-toxic oligomers lacking β-sheet content after subjecting them to proteinase K digestion.…”
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1808
Salivary α-amylase activity is associated with cardiometabolic and inflammatory biomarkers in overweight/obese, non-diabetic Qatari women
Published 2024“…Additionally, sAAa demonstrated a significant positive association with adiponectin β 0.007 [95% CI 0.001 to 0.01]while concurrently displaying significant negative associations with CRP β -0.02 [95% CI -0.044 to -0.0001], TNF-α β -0.105 [95% CI -0.207 to -0.004], IL-6 β [95% CI -0.39 -0.75 to -0.04], and ghrelin β -5.95 [95% CI -11.71 to -0.20], specifically within the female population.…”
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1809
The impact of enteric coating of aspirin on aspirin responsiveness in patients with suspected or newly diagnosed ischemic stroke: prospective cohort study: results from the (ECASIS...
Published 2022“…Univariate and multivariate logistic regression analysis showed that patients treated with EC-ASA were more likely to have a lower rate of non-responders compared to P-ASA (unadjusted OR 0.78; 95% CI 0.20, 3.11); with the risk highest in type 2 diabetic patients with HBA1c > 6.5% (adjusted OR 6; 95% CI 1.02, 35.27; P = 0.047). …”
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1810
Overview of Artificial Intelligence–Driven Wearable Devices for Diabetes: Scoping Review
Published 2022“…<h3>Background</h3><p dir="ltr">Prevalence of diabetes has steadily increased over the last few decades with 1.5 million deaths reported in 2012 alone. …”
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1811
Exercise training-induced speeding of VO<sub>2 </sub>kinetics is not intensity domain-specific or correlated with indices of exercise performance
Published 2024“…Despite significant increases in maximal VO<sub>2</sub> (VO<sub>2max</sub> ), estimated lactate threshold (θLT), maximal metabolic steady state (MMSS), and peak power output (PPO) for the intervention groups (p < 0.05), there were no significant correlations from PRE to MID or MID to POST between ΔτVO<sub>2</sub> and Δ V O<sub>2max</sub> (r=– 0.221, r = 0.119), ΔPPO (r= – 0.112, r= – 0.017), ΔθLT (r= 0.083, r = 0.142) and ΔMMSS (r= – 0.213, r = 0.049)(p > 0.05).…”
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1812
In vitro effects of multi-purpose contact lens disinfecting solutions towards survivability of Acanthamoeba genotype T4 in Malaysia
Published 2021“…The incidence of Acanthamoeba keratitis has been increasing since the previous decades, especially among contact lens users. …”
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1813
Exploring Unique Physiological and Genetic Features of Desert-dwelling Legumes
Published 2025“…Our presented work will support several crop improvement programs to design research strategies ensuring improved environmental stress tolerance to legumes and non-legumes and eventually address the world food insecurity to a great extent.…”
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1814
Fixed Shading Scenarios to Optimize Lighting Performance and Energy Efficiency in Office Buildings Case Study of Dubai Design District
Published 2021“…The results in chapter 5 show that the Egg-crate scheme performed most effectively on the office building case study achieving a reduction in energy consumption of 8.2% from the base case result in a year. …”
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1815
Efficacy and safety of using Etelcalcetide for controlling secondary hyperparathyroidism
Published 2024“…<h3>Background</h3><p dir="ltr">In Qatar, secondary hyperparathyroidism (SHPT) is a common problem in haemodialysis (HD) patients, associated with significant clinical consequences for Chronic Kidney Disease (CKD) patients, including osteitis fibrosa cystica and calcific cardiovascular disease, broadly referred to as CKD–mineral bone disorder. …”
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1816
Masked phenomenon: renal and cardiovascular complications; review and updates
Published 2024“…Normal blood pressure should be 120/80 mmHg, which generally decreases when a person is sleeping or sitting. High blood pressure or hypertension occurs when the blood pressure is too high. …”
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1817
An ensemble-based machine learning model for predicting type 2 diabetes and its effect on bone health
Published 2024“…ML models were utilized to distinguish diabetes groups from non-diabetes controls. Recursive feature elimination (RFE) was leveraged to identify a subset of features to improve the performance of model. …”
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1818
From past famines to present crises: The epigenetic impact of maternal malnutrition on offspring health in Gaza
Published 2024“…Notably, at least one in four households (over half a million people) are facing catastrophic conditions (IPC Phase 5, Catastrophe) according to the IPC.…”
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1819
The Effect of Atorvastatin (and Subsequent Metformin) on Adipose Tissue Acylation-Stimulatory-Protein Concentration and Inflammatory Biomarkers in Overweight/Obese Women With Polyc...
Published 2019“…</p><p><br></p><p dir="ltr">ISRCTN Number: ISRCTN24474824</p><h2>Other Information</h2><p dir="ltr">Published in: Frontiers in Endocrinology<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3389/fendo.2019.00394" target="_blank">https://dx.doi.org/10.3389/fendo.2019.00394</a></p>…”
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1820
HIV incidence among people who inject drugs in the Middle East and North Africa: mathematical modelling analysis
Published 2018“…It also delineates injecting drug use role as a driver of the epidemic in the population, and estimates impact of interventions.…”