Spatiotemporal Dynamics of β-Adrenergic cAMP Signals and L-Type Ca2+ Channel Regulation in Adult Rat Ventricular Myocytes by Leroy, Jerome

“…Consistently, cAMP-PDE assay on ARVMs briefly (15 seconds) exposed to isoprenaline showed a pronounced (up to ≈50%) dose-dependent increase in total PDE activity, which was mainly attributable to activation of PDE4. …”
Get full text
Get full text
Get full text
Get full text

DNA Base-Calling Techniques by Odeh, Fadi

Get full text

T-cell-derived interleukin-17 regulates the level and stability of cyclooxygenase-2 (COX-2) mRNA through restricted activation of the p38 mitogen-activated protein kinase cascade by Faour, Wissam

“…In preliminary work, recombinant human (rh) IL-17 stimulated a rapid (5–15 min), substantial (>8-fold), and sustained (>24 h) increase in COX-2 mRNA, protein, and prostaglandin E2 release. …”
Get full text
Get full text
Get full text

Brain and plasma riluzole pharmacokinetics by Milane, Aline

Get full text
Get full text
Get full text
Get full text

Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017) by Khalil, Nathalie

“…All the PC cell lines investigated exhibited G0/G1 cell cycle arrest at 72 hours following arginine depletion treatment. Additionally, all five PC cell lines stained negative for annexin V and showed the lack of caspase activation following 24 and 48 hours of arginine deprivation. …”
Get full text
Get full text
Get full text

Strain rate effect on twip/trip high entropy alloy by El Batal, Omar Mohammad Marwan

Get full text

Sensibilisation du baroréflexe sympathique durant le stress émotionnel chez le rat by Kanbar, R.

“…The latter effect was a consequence of an increase (P ≪ 0.01) in the maximal range of variations of RSNA (from 285 ± 33 to 619 ± 59 NU). …”
Get full text
Get full text
Get full text
Get full text

Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal by Zehra Irshad (18614869)

“…</p><p><br></p><h2>Other Information</h2><p dir="ltr">Published in: Scientific Reports<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1038/s41598-019-44358-1" target="_blank">https://dx.doi.org/10.1038/s41598-019-44358-1</a></p>…”

The sympathetic baroreflex is enhanced during emotional stress in rats by Kanbar, Roy

“…The latter effect was a consequence of an increase (P<0.01) in the maximal range of variations of RSNA (from 285 +/- 33 to 619 +/- 59 NU). …”
Get full text
Get full text
Get full text
Get full text

Simultaneous Resections of Colorectal Cancer and Synchronous Liver Metastases by Reddy, Srinevas

Get full text
Get full text

Is extended hepatectomy for hepatobiliary malignancy justified? by Abdalla, Eddie

“…The median survival was 41.9 months. The overall 5-year survival rate was 25.5%. Conclusions: Extended hepatectomy can be performed with a near-zero operative mortality rate and is associated with long-term survival in a subset of patients with malignant hepatobiliary disease. …”
Get full text
Get full text
Get full text

Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide. by Sara, Sokary

“…Also, it enhanced glycemic control, as evidenced by significant reductions in hemoglobin A1C (HbA1c) with the 0.5 mg and 1.0 mg doses. From a baseline range of 8.1–8.7%, 0.5mg dose lowered HbA1c by 1.2–1.5%, while the 1.0 mg dose reduced it by 1.4–1.8%. …”
Get full text
Get full text
Get full text

Prostaglandin E2 regulates the level and stability of cyclooxygenase-2 mRNA through activation of p38 mitogen-activated protein kinase in interleukin-1β-treated human synovial fibr... by Faour, Wissam

“…We observed a rapid (5 min), massive (>30-fold), and sustained (>48 h) increase in COX-2 mRNA, protein, and PGE2 release following a recombinant human (rh) IL-1β signal that was inhibited by NS-398, a COX-2 inhibitor, and SB202190, a selective, cell-permeable p38 MAPK inhibitor. …”
Get full text
Get full text
Get full text

Patients’ Perspectives About Factors Affecting Their Use of Electronic Personal Health Records in England: Qualitative Analysis by Alaa Abd-Alrazaq (17430900)

“…A convenience sample was recruited in 4 GPs in West Yorkshire, England. …”

Beauvericin potentiates the activity of pesticides by neutralizing the ATP-binding cassette transporters in arthropods by Charbel Al Khoury (13167975)

“…</p><h2>Other Information</h2> <p> Published in: Scientific Reports<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1038/s41598-021-89622-5" target="_blank">http://dx.doi.org/10.1038/s41598-021-89622-5</a></p>…”

Tranexamic acid for the prevention of blood loss after cesarean section: an updated systematic review and meta-analysis of randomized controlled trials by Huzaifa Ahmad Cheema (16328980)

“…</p> <h3>Methods</h3> <p>We used the revised Cochrane “Risk of Bias" tool (RoB 2.0) to assess the quality of included RCTs. RevMan 5.4 was used to conduct all statistical analyses under a random-effects model.…”

National-level and state-level prevalence of overweight and obesity among children, adolescents, and adults in the USA, 1990–2021, and forecasts up to 2050 by Marie, Ng

“…For individuals older than 18 years, overweight was defined as having a BMI of 25 kg/m2 to less than 30 kg/m2 and obesity was defined as a BMI of 30 kg/m2 or higher, and for individuals younger than 18 years definitions were based on International Obesity Task Force criteria. …”
Get full text
Get full text
Get full text

The E3 ubiquitin-protein ligase UHRF1 promotes adipogenesis and limits fibrosis by suppressing GPNMB-mediated TGF-β signaling by Muneera Vakayil (12037693)

National-level and state-level prevalence of overweight and obesity among children, adolescents, and adults in the USA, 1990–2021, and forecasts up to 2050 by Marie, Ng

“…For individuals older than 18 years, overweight was defined as having a BMI of 25 kg/m2 to less than 30 kg/m2 and obesity was defined as a BMI of 30 kg/m2 or higher, and for individuals younger than 18 years definitions were based on International Obesity Task Force criteria. …”
Get full text
Get full text
Get full text

Effect of Surgical Margin Status on Survival and Site of Recurrence After Hepatic Resection for Colorectal Metastases by Pawlik, Timothy

“…Results: On final pathologic analysis, margin status was positive in 45 patients, and negative by 1 to 4 mm in 129, 5 to 9 mm in 85, and ≥1 cm in 298. At a median follow-up of 29 months, the 1-, 3-, and 5-year actuarial survival rates were 97%, 74%, and 58%; median survival was 74 months. …”
Get full text
Get full text
Get full text