SARS-CoV-2-specific CD4 and cTfh responses decrease in magnitude in late convalescence. حسب Sushma Boppana (7181300)

The gut microbiome and metabolome in kidney transplant recipients with normal and moderately decreased kidney function حسب Yang Lan (1750390)

Locations of projected refugia for all five taxa with 2°C and 4.5°C warming. حسب Rhosanna L. M. Jenkins (11167230)

Spleen PAX5 significantly decreased in APRIL/BLyS blockade treated mice. حسب Natalie M. Bath (6316517)

Detection of the Challenging mutations at 1% VAF and 50 ng DNA input. حسب Lizhi Yu (12476136)

الموضوعات:

Sulforaphane decreases IL-6, TNF-α, IL-17, and total IgG levels. حسب Su-Jin Moon (424173)

Locations of refugia with 2°C and 4.5°C warming. حسب Rhosanna L. M. Jenkins (11167230)

Excision of HIF1α decreases viral reactivation from latency in infected splenocytes in vivo. حسب Darlah M. López-Rodríguez (8098544)

Loss of virulence in the SIN kinase mutants is characterized by decreased fungal burden and host response to infection. حسب Ana Camila Oliveira Souza (8180958)

"…<i>fumigatus</i> specific DNA in 500 ng of total DNA. * p < 0.02. Quantitation of IL-1β <b>(B)</b> and TNFα <b>(C)</b> revealed decreased host response in SIN kinase mutant infected mice. …"

Knock-down of Atox1 in SW620 cells decreased cell migration and colony formation. حسب Arundhati Jana (157555)

Hydroxymethylnitrofurazone (NFOH) decreases parasitaemia, parasitism and tissue lesion caused by infection with the Bolivia Trypanosoma cruzi type I strain in Swiss and C57BL/6 mic... حسب Cauê Benito Scarim (5222987)

"…In both experimental murine models, NFOH was able to reduce parasitemia blood avoiding parasitic reactivation, during immunosuppression period (dexamethasone 5mg/kg, 14 days), in 100% of the mice, and decrease tissue parasite nests, demonstrating absence of amastigote forms in all organs (100%) analyzed, data similar to benznidazole (BZN). …"

Changes of peritoneal structure and function in rats. حسب Yangyang Yin (14323701)

الموضوعات:

The effect of MiR-132-3p on protein expression in TGF-<i>β</i>1/Smad2/3 signaling pathway was observed by immunofluorescence. حسب Yangyang Yin (14323701)

الموضوعات:

Maximum concentrations (ng/L) of 88 pharmaceuticals detected at least once (in order of decreasing number of detections across all regions and samples) in water samples from wadeab... حسب Paul M. Bradley (523469)

Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model حسب Christopher C. Marvin (1338228)

"…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. The anti-mTNF conjugate <b>ADC5</b> fully inhibited inflammation in mouse contact hypersensitivity with minimal effects on corticosterone, a biomarker for systemic GRM effects, at doses up to and including 100 mg/kg. …"

Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model حسب Christopher C. Marvin (1338228)

"…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. The anti-mTNF conjugate <b>ADC5</b> fully inhibited inflammation in mouse contact hypersensitivity with minimal effects on corticosterone, a biomarker for systemic GRM effects, at doses up to and including 100 mg/kg. …"

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations حسب Hui Li (32376)

"…Here, we evaluated the aging and neurodegenerative effects of F-53B using the C. elegans model. After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …"

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations حسب Hui Li (32376)

"…Here, we evaluated the aging and neurodegenerative effects of F-53B using the C. elegans model. After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …"

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations حسب Hui Li (32376)

"…Here, we evaluated the aging and neurodegenerative effects of F-53B using the C. elegans model. After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …"

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in <i>C. elegans</i> at Low Concentrations حسب Hui Li (32376)

"…Here, we evaluated the aging and neurodegenerative effects of F-53B using the C. elegans model. After exposure to F-53B at 2, 10, and 50 ng/L, C. elegans showed an aging phenomenon as lipofuscin was significantly increased by 48.7–57.5% and locomotion, such as center point speed, was significantly decreased in all exposure groups. …"