CMS121 and C75 reduce the infectivity of HSV-1 viral particles. by Camilla Albano (16446679)

Homozygous deletion of <i>ERG251</i> results in decreased fitness at low initial cell density and increased fitness in the presence of low concentrations of FLC (≤1μg/ml). by Xin Zhou (54275)

Mutations eliminating positive charge from the C-terminal helix of UNO decrease chromatin binding of SU and interfere with normal chromosome conjunction during meiosis. by Zeynep Kabakci (9449519)

<i>Emx1</i>-cKO mice lack the neocortex. by Sathish Venkataramanappa (10331993)

Association between dietary flavonoid and decreased eGFR/increased uACR in the US population. by Peijia Liu (3694051)

Histograms of model vertex von Mises stress values exceeding 5 MPa. by Nathan L. Wright (18389458)

NatB inactivation decreased the level of MAPK and proposed model of EGFR/MAPK signaling regulation by NatB and the N-end rule pathways. by Zhentao Sheng (107495)

“…(C) <i>psid-D4</i> clones in wing disc, marked by GFP expression (pointed by arrowheads), showed decreased MAPK level. …”

Reduction of OPL and decreased number of horizontal cells in P18 Oc-deficient mice. by Michaela Kreplova (9239560)

TG6-44 treatment leads to decrease in A/X31-induced cell death in THP-1 cells. by Juan A. De La Cruz (11154187)

EGFR/ERK signaling activity decreases throughout LEC elimination with endocytic activity dependency. by Kevin Yuswan (19845885)

Alternative bounded and monotonically decreasing functions do not accurately fit the bias in the naïve SI. by Liron Sheintuch (12078310)

“…<p>(A-D) Fitting the naïve SI (blue) of simulated data using different types of bounded and monotonically decreasing functions with three free parameters. BAE (green; C) yields a more accurate estimation of the true SI (cyan) compared to an exponential function (red; A) or a power law (magenta; B). …”

FTY720 decreased viability, proliferation, and motility and induced apoptosis in human hepatoblastoma cells. by Laura L. Stafman (6577184)

“…<p>(A) Following 24 hours of treatment with FTY720, the viability of HuH6 cells measured using the alamarBlue cell viability assay was significantly decreased (LD₅₀ = 8.4 μM, p ≤ 0.05). (B) Following 24 hours of treatment with FTY720, the proliferation of HuH6 cells measured using the CellTiter 96 cell proliferation assay was significantly decreased (IC₅₀ = 6.4 μM, p ≤ 0.05). …”

Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(F)</b> qPCR analysis for cholesterogenic genes from NIH3T3 cells exposed to cholesterol (50 μm) or 25-hydroxycholesterol (10 μm) under 5% or 1% CO₂ for 4 h (mean ± SE, <i>n</i> = 3 biological replicates per condition, ***<i>P</i> < 0.001, nonsignificant (ns), two-way ANOVA with Bonferroni’s multiple comparisons test). …”

SARS-CoV-2-specific CD4 and cTfh responses decrease in magnitude in late convalescence. by Sushma Boppana (7181300)

Expression of ApoB-50 decreased lipid accumulation and inhibited HCV production. by Bei Wang (116772)

Prb1 overexpression decreased APCs in ESCRT-mutant cells after nitrogen starvation. by Zulin Wu (4451572)

“…Either Prb1 or Snf7 in <i>snf7Δ</i> cells facilitated GFP-Atg8 degradation and prApe1 maturation (bottom), but only Snf7 (not Prb1) facilitated phagophore closure in <i>snf7Δ</i> cells. The red arrows point to these key results. <b>F.</b> The blots shown in panel E were quantified as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010431#pgen.1010431.g006" target="_blank">Fig 6A and 6B</a>. …”

Deletion of <i>sagA</i> alone results in a decrease in nasopharyngeal infection. by Blake A. Shannon (14197601)

Hematoxylin and eosin (H&E) staining, Sirius Red staining, and Oil Red staining of liver tissues from mice in each group after 8 weeks of treatment with either vehicle or Kylo-0603... by Xueqin lu (22250795)

Locations of projected refugia for all five taxa with 2°C and 4.5°C warming. by Rhosanna L. M. Jenkins (11167230)

Spleen PAX5 significantly decreased in APRIL/BLyS blockade treated mice. by Natalie M. Bath (6316517)