Cytotoxicity of [HuArgI (co)-PEG5000]-induced arginine deprivation to ovarian Cancer cells is autophagy dependent by Nasreddine, Ghenwa

“…Ovarian cancer cell lines were negative for annexinV staining while showing loss of membrane integrity and absence of caspase activation, indicating caspase-independent, non-apoptotic cell death. [HuArgI (Co)-PEG5000]-induced arginine deprivation led to extensive and prolonged activation of autophagy, which proved to be deleterious to cell survival since its inhibition led to a significant decrease in cytotoxicity. …”
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The contribution of autophagy in glioblastoma multiforme cells treated with human recombinant arginase I-induced arginine deprivation. (c2018) by El Jbeily, Elie

“…Moreover, it is resistant to traditional chemotherapies and radiotherapies. All this results in a poor survival rate in GBM patients, which doesn’t exceed 1 year. …”
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A Numerical Study of Heat Transfer and Fluid Flow in a Channel with an Array of Pin Fins in Aligned and Staggered Configurations by Issa, Johnny

“…The dimensionless spacing, S*, defined as the ratio of the gap between the fin walls to the fin diameter, is varied between a value of 0.5 and 1. Nine different approaching velocities are considered in this study which resulted in Reynolds number values ranging between 5 and 160. …”
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Secrecy Performance of a RIS-Assisted Wireless Network: A Comprehensive Analysis Under Outdated CSI by Tasneem Alshamaseen (22392382)

“…Moreover, increasing the number of REs can mitigate CSI aging effects where an SOP level of 3×10⁻⁵ can be achieved with 140 REs at <i>ρ</i>=0.9 in the absence of a transmitter-receiver direct link. …”

Women’s empowerment as a determinant of neonatal mortality in Sub-Saharan Africa: a narrative review focused on Nigeria by Joel-Medewase Victor Idowu (22155178)

“…</p><h2>Other Information</h2><p dir="ltr">Published in: Global Health Action<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1080/16549716.2024.2394256" target="_blank">https://dx.doi.org/10.1080/16549716.2024.2394256</a></p>…”

Origin of arrhythmias in a heart model by Sheheitli, Hiba

“…An investigation of the nonlinear dynamics of a heart model is presented. The model compartmentalizes the heart into one part that beats autonomously (the x oscillator), representing the pacemaker or SA node, and a second part that beats only if excited by a signal originating outside itself (the y oscillator), representing typical cardiac tissue. …”
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Screening for antiretroviral drug resistance among treatment-naive human immunodeficiency virus type 1-infected individuals in Lebanon by Mokhbat, Jacques M.

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Wales’ tourists not a burden for local healthcare by Nature Research (16552612)

“…</i></p><p></p><h2>Other Information</h2><p>Published in: QScience.com Highlights, Published by Nature Research for Hamad bin Khalifa University Press (HBKU Press)<br>License: <a>http://creativecommons.org/licenses/by/4.0</a><br></p>…”

A clustering metaheuristic for large orienteering problems by Almiqdad Elzein (13141038)

“…</p><h2 dir="ltr">Other Information</h2><p dir="ltr">Published in: PLOS ONE<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1371/journal.pone.0271751" target="_blank">https://dx.doi.org/10.1371/journal.pone.0271751</a></p>…”

When Should a Brain MRI Be Performed in Children with New-Onset Seizures? Results of a Large Prospective Trial by Hourani, R.

“…Univariate analysis showed a significant increase in the frequency of epileptogenic lesions with decreasing age, the presence of developmental delay, and the number and types of seizures at presentation. …”
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Prehospital plasma transfusion versus standard of care following traumatic injury: a review of the systematic reviews and a meta-analysis by Ayman El-Menyar (440103)

“…</p><h2 dir="ltr">Other Information</h2><p dir="ltr">Published in: European Journal of Trauma and Emergency Surgery<br>License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1007/s00068-025-03033-z" target="_blank">https://dx.doi.org/10.1007/s00068-025-03033-z</a></p>…”

Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells by Ejlal Abu-El-Rub (5168183)

“…Similarly, genetic knockdown of HSP90 in RKO cells produced comparable effects, including reduced cell survival and a decreased PINK1/BNIP3 ratio.</p><h3>Conclusion</h3><p dir="ltr">Targeting HSP90 in colon cancer cells disrupts their survival by decreasing PINK1 and increasing BNIP3, which activates oxidative and endoplasmic reticulum stress, ultimately triggering apoptosis.…”

Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection? by Abu Saleh Md Moin (6189512)

“…<h3>Introduction</h3><p dir="ltr">Neuropilin-1(NRP1) is a cofactor that enhances SARS-CoV-2 coronavirus cell infectivity when co-expressed with angiotensin-converting enzyme 2(ACE2). …”

Exploring The Effect of [HuArgI (Co)-PEG5000]-Induced Autophagy on The Migration, Adhesion, And Invasion of U87 Glioblastoma cells by Haidar, Sara

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Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes by Maryam Aghadi (17128819)

“…Functional assays demonstrated an increase in lipid accumulation, bile acid synthesis and glycerol production, while a decrease in glucose uptake, glycogen storage, and Albumin secretion. …”

The role of RhoG in migration and invasion of glioblastoma cells. (c2017) by Ezzeddine, Amani M.

“…Finally, a pull-down assay was done for the Rho family of GTPases which showed that RhoG downregulates RhoA and Rac1 activation levels. …”
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A cluster-based model for QoS-OLSR protocol by Otrok, Hadi

“…The QOLSR is a multimedia protocol that was designed on top of the Optimized Link State Routing (OLSR) protocol. …”
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A potential therapeutic agent for sickle cell anaemia by Nature Research (16552612)

“…</p><p>Patients with sickle cell anaemia produce 10 to 30 times more of a natural by-product of oxygen metabolism called reactive oxygen species (ROS) than healthy patients. …”

The DJ-1 superfamily members YhbO and YajL from Escherichia coli repair proteins from glycation by methylglyoxal and glyoxal by Abdallah, Jad

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Crystallization properties of arsenic doped GST alloys by Vinod E. Madhavan (8136774)

“…Though both the GST and arsenic doped GST are amorphous in the as-deposited state, only GST alloy turns to crystalline NaCl-type structure after annealing at 150 °C for 1 h. Results from the resistance versus temperature study show a systematic increase in the transition temperature and resistivity in the amorphous and crystalline states when the arsenic percentage in the GST alloy increases. …”