Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit Masania (7164239)

“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”

Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit, Masania

“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Fetoplacental transmission and placental response to SARS-CoV-2: Evidence from the literature by Henry C. Ezechukwu (13253406)

“…To date, the vertical transmission of SARS-CoV-2 during pregnancy remains controversial. We briefly report recent findings of placental response to SARS-CoV-2 infection and updates on vertical transmission. …”

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Vijay Ganji (8710491)

Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications by Jingxuan Shan (4711089)

“…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …”

COVID-19 and Anemia: What Do We Know So Far? by Luai Abu-Ismail (10712857)

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

“…By elucidating a mechanistic basis for the increased affinity of the N501Y mutant S1-RBD for ACE2, we believe that the results presented here will aid in developing therapeutic strategies against SARS-CoV-2 including designing of therapeutic agents targeting the ACE2-S1-RBD interaction.…”

Ferroelectric Properties and Electrocaloric Effect in Dy2O3 Substitution on Lead-Free (Na0.5 Bi0.5)0.94 Ba0.06TiO3 Ceramic by Turki, O.

“…We report the impact of dysprosium (Dy, with y = 0.01, 0.02, 0.05 and 0.08) substitution in (Na0.5 Bi0.5)0.94 Ba0.06TiO3 (NBT-6BT) lead-free ceramics. …”
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A genetically encoded BRET-based SARS-CoV-2 Mpro protease activity sensor by Anupriya M. Geethakumari (17052375)

“…Further, in vitro assays with the BRET-based Mpro sensors revealed a molecular crowding-mediated increase in the rate of M^pro activity and a decrease in the inhibitory potential of GC376. The sensors developed here will find direct utility in studies related to drug discovery targeting the SARS-CoV-2 M^pro and functional genomics application to determine the effect of sequence variation in M^pro.…”

Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burd... by Katherine R Paulson (8674293)

“…</p><p><br></p><h3>Methods</h3><p dir="ltr">We completed all-cause mortality and cause-specific mortality analyses from 204 countries and territories for detailed age groups separately, with aggregated mortality probabilities per 1000 livebirths computed for neonatal mortality rate (NMR) and under-5 mortality rate (U5MR). …”

Sleeve Gastrectomy in Patients with Type 2 Diabetes: Anthropometric and Cardiometabolic Improvements at 1, 3, 5, 7, and 9 years—Are the Initial Benefits Sustained? by Wahiba Elhag (5245547)

“…We appraised the evolution of 20 outcomes at 1, 3, 5, 7, and 9 years.…”

The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... by Wesal Habbab (17346961)

The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR) by Varghese P. Inchakalody (14557382)

“…We also observed the differential expression of protein Complement C3 (3.3-fold), Destrin (−5.1-fold), Vimentin (−1.7-fold), Peroxiredoxin 4 (−1.6-fold), Fascin (−1.8-fold), Heme oxygenase-2 (−0.67-fold**p < 0.0055), Hsp27 (−0.57-fold**p < 0.004), and Hsp70 (−0.39-fold **p < 0.001), indicating reduced cell growth, cell migration, and metastasis. …”

Crystallization properties of arsenic doped GST alloys by Vinod E. Madhavan (8136774)

“…<p dir="ltr">We present the enhanced properties observed in the phase change memory alloy Ge₂Sb₂Te₅ (GST) when doped with arsenic. …”

Solar hydrogen production via thermochemical magnesium oxide – Magnesium sulfate water splitting cycle by Rahul R. Bhosale (6467102)

“…<p dir="ltr">This investigation reports the thermodynamic scrutiny of the MgO/MgSO₄ water-splitting cycle. At the initial stage, the thermal reduction temperature required for the commencement of the thermal dissociation of MgSO₄ (in the absence of inert Ar) and the maximum temperature below which the water-splitting reaction is feasible is identified by performing thermodynamic equilibrium calculations. …”

Impact of trace noble metals on the catalytic performance of LaNiMgO towards methane dry reforming by Mohamed, Assem T.

“…On the other hand, at the same time-on-stream LaNiMgO-Rh lost 0.3 and 0.7 % of its maximum CO2 and CH4 conversions, respectively.In durability measurements, and after 140h LaNiMgO-Rh exhibited slight decay in the CO2 conversion from 77.6 % to 70.5%, the CH4 conversion decreased from 72.3% to 64.2%. …”
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Impact of trace noble metals on the catalytic performance of LaNiMgO towards methane dry reforming by Yahia H. Ahmad (14340210)

“…In durability measurements, and after 140h LaNiMgO-Rh exhibited slight decay in the CO₂ conversion from 77.6 % to 70.5%, the CH₄ conversion decreased from 72.3% to 64.2%. …”

Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications by Sumama Nuthana Kalva (17302906)

“…Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”

Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells by Mohamed Qasim, Al-Fahdawi

“…The cytotoxicity of Pt/MgO nanoparticles was determined via the 3-(4,5-dimethylthiazol-2-yl)−2,5-diphenyltetrazolium bromide assay on the human lung and colonic cancer cells (A549 and HT29 respectively) and normal human lung and colonic fibroblasts cells (MRC-5 and CCD-18Co repectively). …”
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BRET-based biosensors for SARS-CoV-2 oligonucleotide detection by Asfia Sultana (19170880)

“…Specifically, we designed BioODs against the SARS-CoV-2 parental (Wuhan strain) and B.1.617.2 Delta variant through the conjugation of specific, fluorescently modified molecular beacons (sensor module) through a complementary oligonucleotide handle DNA functionalized with the NanoLuc (NLuc) luciferase protein such that the dissolution of the molecular beacon loop upon the binding of the viral oligonucleotide will result in a decrease in BRET efficiency and, thus, a change in the bioluminescence spectra. …”