Showing 141 - 160 results of 34,559 for search '(( 5 c decrease ) OR ((( 50 ng decrease ) OR ( 100 ((ng decrease) OR (a decrease)) ))))', query time: 0.77s Refine Results
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    Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

    Published 2024
    “…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. …”
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    Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

    Published 2024
    “…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. …”
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    Decreased expression of SAGA components, ERBB2, and ERBB3 upon deletion of <i>Usp22</i> in mammary gland epithelial cells (MECs) collected from 100-day old NIC mice. by Xianghong Kuang (17811238)

    Published 2024
    “…HSP70, HSP90AB1 and HSP90 protein levels were not affected when analyzed by western blotting in the same lysates. n = 3 for each group. (B, C) qRT-PCR analysis of total RNA collected from <i>Usp22</i><sup><i>FL/FL</i></sup><i>- NIC</i> MECs confirmed that mRNA levels of <i>Usp22</i> and <i>Erbb2</i> were drastically decreased compared to <i>Usp22</i><sup><i>+/+</i></sup><i>- NIC</i>. p<0.0001 for both <i>Usp22</i> and <i>Erbb2</i>, as determined by two-tailed unpaired t test. n = 5 for each group. …”
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    GSK343 treatment decreased <i>in vivo</i> tumor volume and growth. by Laura V. Bownes (10276762)

    Published 2021
    “…Tumor volumes were monitored three times per week. (A) Animals treated with GSK343 had significantly decreased fold change in tumor volumes compared to mice treated with vehicle. …”