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ns decrease » nn decrease (Expand Search), _ decrease (Expand Search), a decrease (Expand Search)
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50 ns » 50 ms (Expand Search)
5 c » 25 c (Expand Search)
ns decrease » nn decrease (Expand Search), _ decrease (Expand Search), a decrease (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
c decrease » c decreased (Expand Search), _ decrease (Expand Search), a decrease (Expand Search)
50 ns » 50 ms (Expand Search)
5 c » 25 c (Expand Search)
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Discovery of New Inhibitors of Hepatitis C Virus NS3/4A Protease and Its D168A Mutant
Published 2019“…However, in the same assay, the potency of the approved drug, simeprevir, decreased 5.7-fold for the mutant enzyme relative to the wild type. …”
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Atomically Precise Au<sub>42</sub> Nanorods with Longitudinal Excitons for an Intense Photothermal Effect
Published 2022“…Compared to other rod-shaped nanoclusters, Au<sub>42</sub> possesses a much more effective photothermal conversion with a large temperature increase of ∼27 °C within 5 min (λ<sub>ex</sub> = 808 nm, 1 W cm<sup>–2</sup>) at an ultralow concentration of 50 μg mL<sup>–1</sup> in toluene. …”
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Disrupting Glycolysis-promoting Genes Extends <i>C</i>. <i>elegans</i> Healthspan, Whereas High Glucose and Gluconeogenic Gene Disruptions Shorten Healthspan.
Published 2020“…We note that, in our hands, disruption of C50F4.2 (<i>pfk-1</i>.…”
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DAF-16/FOXO is Required for Locomotory Healthspan and Lifespan Benefits of Genetic Glycolysis Disruption.
Published 2020“…WT later in life [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008982#pgen.1008982.ref091" target="_blank">91</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008982#pgen.1008982.ref092" target="_blank">92</a>]; we note that, although comparison of scores across experiments is not possible due to variation in baseline values, the swimming rate of <i>daf-16(mgDf50)</i> control animals was slightly lower than WT controls on the same day of life (in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008982#pgen.1008982.g001" target="_blank">Fig 1C</a>; mean of 46.17 head thrashes/30 sec. for <i>daf-16</i> vs. 52.17 head thrashes/30 sec. for WT on day 10). …”
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Neurochemical identity of dFB<sup>23E10</sup>Ո<sup>84C10</sup> neurons.
Published 2025“…<b>(G)</b> Quantification of the numbers of dFB neurons contained within the 2 Split-GAL4 lines presented in E and F. We observed 16.00 ± 0.41 (<i>n</i> = 4) dFB cells for <i>84C10-AD; ChAT-DBD</i> and 22.20 ± 0.49 (<i>n</i> = 5) dFB neurons for <i>VGlut-AD; 84C10-DBD.…”