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Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
Published 2023“…As oncogenic transcriptomic downregulation is often driven by methylation of the promotor region, we explore the demethylation effect of 5-aza-2′-deoxycytidine (decitabine), on the SLFN11 gene. …”
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102
Enhanced oil recovery using hyperbranched polyglycerol polymer-coated silica nanoparticles
Published 2021“…A D<sub>PSiMNPs</sub> = 100 mg/L was sufficient to achieve %η<sub>dem</sub> of 99.4% for C<sub>oil</sub> = 100 mg/L and slightly decreased to ~93% for C<sub>oil</sub> ~4000 mg/L. …”
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103
Insulin detemir in combination with oral antidiabetic drugs improves glycemic control in persons with type 2 diabetes in Near East countrie
Published 2017“…Mean FPG decreased significantly from 213.7 ± 60.1 mg/dL to 120.3 ± 25.7 mg/dL (P<.001), and mean PPG from 271 ± 65.3 mg/dL to 158.1 ± 36.4 mg/dL (P<.0001). …”
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Comparative proteomic analysis of a Candida albicans DSE1 mutant under filamentous and non-filamentous conditions
Published 2014“…The DSE1 mutant was shown to lack the chitin biosynthesis protein Chs5, explaining the previously observed decrease in chitin biosynthesis. …”
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Did the periodic intensification of routine immunisation strategy (Intensified mission Indradhanush) reduce the demand for pediatric antibiotic formulations in India?
Published 2025“…We conducted interrupted time series analyses by fitting a Poisson regression model. …”
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Glycemic outcomes of Advanced Hybrid Closed Loop system in children and adolescents with Type 1 Diabetes, previously treated with Multiple Daily Injections (MiniMed 780G system in...
Published 2022“…</p><h3>Methods</h3><p dir="ltr">In this prospective open label single-arm, single-center, clinical investigation, we recruited children and adolescents (aged 7–17 years) with T1D on MDI therapy and HbA1c below 12.5%. …”
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10-Day structured initiation protocol from multiple daily injection to hybrid closed-loop system in children and adolescents with type 1 diabetes
Published 2020“…The participants used the sensor for a median of 92% of the time and spent a median of 89% in Auto Mode. The mean HbA1c decreased from 8.2 ± 1.4% (66 ± 15.3 mmol/mol) at baseline to 6.7 ± 0.5% (50 ± 5.5 mmol/mol) at the end of the study (p = 0.017). …”
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108
Interleukin-35 and Thymoquinone nanoparticle-based intervention for liver protection against paracetamol-induced liver injury in rats
Published 2023“…Group IV (PAR) received 600 mg/kg of PAR orally; V (PAR + IL-35) and VI (PAR + TYHO); rats received 600 mg/kg of PAR orally and i.p injection of IL-35 (200 ng/kg) or THYO (0.5 mg/kg), respectively. …”
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Efficacy of Lebanese Cannabis Oil Extract in the Treatment of Folic Acid-Induced Renal Fibrosis in Rats
Published 2023“…In addition, a significant decrease in serum creatinine was observed in groups receiving cannabis extract at the doses of 5 and 10 mg/kg. …”
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Impact of composition and salinity on swelling and gel strength of poly (acrylamide-co-acrylic acid) preformed particle gel
Published 2023“…The PPGs also demonstrated the ability to compete with other commercial PPGs as they have shown physical and thermal stability when aging at 50 °C, specifically those with high crosslinker content (PPG5).…”
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112
One-year experience of hybrid closed-loop system in children and adolescents with type 1 diabetes previously treated with multiple daily injections: drivers to successful outcomes
Published 2022“…HbA1c decreased from 8.2 ± 1.4% (66 ± 15.3 mmol/mol) at baseline, to 6.7 ± 0.5% (50 ± 5.5 mmol/mol) at 3 months (p = 0.02) and remained stable to 7.1 ± 0.6 (54 ± 6.6 mmol/mol) at 12 months (p = 0.02). …”
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Anabolic steroids-induced delirium
Published 2020“…He was discharged on haloperidol 7.5 mg and quetiapine 700 mg daily.</p><h3>Conclusion</h3><p dir="ltr">The purpose of this case report is to emphasize on the neuropsychiatric effects and management of anabolic steroids manifested by delirium, increased aggression, hostility, and destructive impulses.…”
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Impact of the COVID-19 pandemic on sexually transmitted infection testing and diagnosis in Lebanon: A retrospective chart review
Published 2024“…MethodsThis was a retrospective analysis of the clinic's database, including data on voluntary counseling and testing (VCT) for HIV, syphilis, hepatitis B virus (HBV), and hepatitis C virus (HCV). We compared the number and types of services provided, and the number and rate of positive VCT diagnoses pre- (Mar 2019–Feb 2020) and post- (Mar 2020–Feb 2021) COVID-19 onset. …”
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Therapeutic Effect of Lebanese Cannabis Oil Extract in the Management of Sodium Orthovanadate-Induced Nephrotoxicity in Rats
Published 2023“…Rats were intraperitoneally injected with 10mg/Kg Sodium orthovanadate for 10 days followed by 5mg/Kg, 10mg/Kg, or 20mg/Kg intraperitoneal injection of Cannabis oil extract starting day 4 till day 10. …”
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116
Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
Published 2008“…In addition, WP1066 decreased the level of c-Myc and survivin in melanoma cells in a dose- and time-dependent manner. …”
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Interactions between riluzole and ABCG2/BCRP transporter
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Human health risks associated with the consumption of groundwater in the Gaza Strip
Published 2023“…Maximum concentrations of the NO3 and F were 365 and 2.6 mg/L, respectively. The results of probabilistic risk assessment using Monte Carlo simulation showed that NO3 and F consumption through drinking water were above the reference dose for 35 % and 5 % of the trials performed, respectively. …”
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Performance and analysis of kappa-carrageenan hydrogel for PFOA-contaminated soil remediation wastewater treatment
Published 2024“…For 2 cm hydrogel thickness, the water flux of 3%kC-0.3%AC and 3%kC-3%V hydrogels was 25.6 LMH and 21.5 LMH, and the corresponding PFOA rejection was 86.9% for 3%kC-0.3%AC and 85.7% for 3%kC-3%V. …”
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Effects of polyphenol‐rich traditional herbal teas on obesity and oxidative stress in rats fed a high‐fat–sugar diet
Published 2023“…Total phenolic contents (TPC) of <i>Hibiscus rosa-sinensis</i> and <i>Zingiber officinalis</i> extracts were found to be 5.82 and 1.45 mg/g of dry plant material, measured as GAE, while total flavonoid contents (TFC) were 9.17 and 1.95 mg/g of dry plant material, measured as CE, respectively. …”