Image_3_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…Moreover, C5aR1 deficiency significantly decreased IMQ-induced infiltration of plasmacytoid dendritic cells (pDCs), monocytes and neutrophils in psoriatic skin lesions and functions of pDCs, evidenced by the remarkable reduction in the IMQ-induced production of interferon-α (IFN-α) and tumor necrosis factor α (TNF-α), and FMS-like tyrosine kinase 3 ligand (FLT3L)-dependent pDCs differentiation. …”

Image_7_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…Moreover, C5aR1 deficiency significantly decreased IMQ-induced infiltration of plasmacytoid dendritic cells (pDCs), monocytes and neutrophils in psoriatic skin lesions and functions of pDCs, evidenced by the remarkable reduction in the IMQ-induced production of interferon-α (IFN-α) and tumor necrosis factor α (TNF-α), and FMS-like tyrosine kinase 3 ligand (FLT3L)-dependent pDCs differentiation. …”

Image_4_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…Moreover, C5aR1 deficiency significantly decreased IMQ-induced infiltration of plasmacytoid dendritic cells (pDCs), monocytes and neutrophils in psoriatic skin lesions and functions of pDCs, evidenced by the remarkable reduction in the IMQ-induced production of interferon-α (IFN-α) and tumor necrosis factor α (TNF-α), and FMS-like tyrosine kinase 3 ligand (FLT3L)-dependent pDCs differentiation. …”

Image_6_C5a/C5aR1 Pathway Is Critical for the Pathogenesis of Psoriasis.JPEG by Quan-you Zheng (713217)

“…Moreover, C5aR1 deficiency significantly decreased IMQ-induced infiltration of plasmacytoid dendritic cells (pDCs), monocytes and neutrophils in psoriatic skin lesions and functions of pDCs, evidenced by the remarkable reduction in the IMQ-induced production of interferon-α (IFN-α) and tumor necrosis factor α (TNF-α), and FMS-like tyrosine kinase 3 ligand (FLT3L)-dependent pDCs differentiation. …”

5-hmC is increased during THP1 macrophage differentiation. by Fangfang Sun (2410654)

Subjects:

SARS-CoV-2 induced lung inflammation is increased with IL-10 blockade and decreased with IFNγ blockade. by Christine E. Nelson (18946410)

DGAT-1 Inhibitor A922500 decreases the pro-inflammatory profile and cell death induced by SARS-CoV-2 infection and reduces the viral load in human monocyte. by Suelen Silva Gomes Dias (9928813)

CSE-treated bronchospheres have decreased spheroid area and increased MUC5AC secretion in the lumen compared to control. by Pranjali Beri (14945400)

Fibγ^Δ5 mice display decreased survival following <i>S. aureus</i> peritonitis. by Oscar Negrón (11965511)

Pathways of macrophages and neutrophils were decreased in Ad26.COV2.S vaccinated compared to sham unvaccinated hamsters. by Malika Aid (7303874)

“…<p><b>(A)</b> Sample-enrichment analysis (SLEA) of pathways of monocytes, macrophages M1 and M2 pathways, and neutrophils signaling at 4 dpi following SARS-CoV-2 challenge in vaccinated hamsters (shown in pink and blue colors), sham unvaccinated hamsters (shown in green) and in naïve control hamsters (shown in red). …”

Decreases in muscle size, muscle force, and TB mass in 3-mo Lmna^HSA-cko mice. by Lei Xiong (334812)

Image_3_Chemical Similarity of Co-occurring Trees Decreases With Precipitation and Temperature in North American Forests.jpg by Brian E. Sedio (10875330)

“…This hypothesis predicts that the many defensive compounds found in plants’ metabolomes should increase in richness and decrease in interspecific similarity with precipitation, temperature, and plant diversity. …”

Image_2_Chemical Similarity of Co-occurring Trees Decreases With Precipitation and Temperature in North American Forests.jpg by Brian E. Sedio (10875330)

“…This hypothesis predicts that the many defensive compounds found in plants’ metabolomes should increase in richness and decrease in interspecific similarity with precipitation, temperature, and plant diversity. …”

Image_1_Chemical Similarity of Co-occurring Trees Decreases With Precipitation and Temperature in North American Forests.jpg by Brian E. Sedio (10875330)

“…This hypothesis predicts that the many defensive compounds found in plants’ metabolomes should increase in richness and decrease in interspecific similarity with precipitation, temperature, and plant diversity. …”

Image_4_Chemical Similarity of Co-occurring Trees Decreases With Precipitation and Temperature in North American Forests.jpg by Brian E. Sedio (10875330)

“…This hypothesis predicts that the many defensive compounds found in plants’ metabolomes should increase in richness and decrease in interspecific similarity with precipitation, temperature, and plant diversity. …”

Proinflammatory signaling pathways were decreased in Ad26.COV2.S vaccinated compared to sham unvaccinated hamsters. by Malika Aid (7303874)

“…Columns correspond to individual animals, and rows correspond to individual pathways scaled across all animals using the z-score R function. <b>(C)</b> Gene heatmaps of the row scaled expression of the leading genes from pathways shown in panel A increased or decreased at 4 dpi in vaccinated hamsters compared to sham unvaccinated and control naïve animals. …”

<i>Med23</i> deletion causes decreased H3K9me2 occupancy among the promoter of <i>Ccl5</i> and <i>Cxcl10</i>. by Zhichao Wang (3570413)

Fig 5 - by Farheen Naz (12646756)

D-4F and L-5F did not affect body, liver and adipose tissue weight gain. by Kristine C. McGrath (8269155)

Subjects:

Longer polyQ sequences decrease the transcriptional activity of AR. by Carlos M. Roggero (11909585)