In silico and in vivo models for Qatari-Specific classical homocystinuria as basis for development of novel therapies. by Ismail, Hesham M

Get full text
Get full text

Acute mercury toxicity modulates cytochrome P450, soluble epoxide hydrolase and their associated arachidonic acid metabolites in C57Bl/6 mouse heart by Amara, Issa E.A.

“…Mercury toxicity was induced by a single intraperitoneal injection (IP) of 2.5mg/kg of mercuric chloride (HgCl2). Our results showed that mercury treatment caused a significant induction of the cardiac hypertrophy markers, atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP); in addition to Cyp1a1, Cyp1b1, Cyp2b9, Cyp2b10, Cyp2b19, Cyp2c29, Cyp2c38, Cyp4a10, Cyp4a12, Cyp4a14, Cyp4f13, Cyp4f15, Cyp4f16 and Cyp4f18 gene expression. …”
Get full text
Get full text

Cutaneous Aβ-Non-nociceptive, but Not C-Nociceptive, Dorsal Root Ganglion Neurons Exhibit Spontaneous Activity in the Streptozotocin Rat Model of Painful Diabetic Neuropathy . by Djouhri, Laiche

“…Compared with control, we found in STZ-rats with established pain hypersensitivity (5 weeks post-STZ) several significant changes including: (a) A 23% increase in the incidence of spontaneous activity (SA) in Aβ-LTMs (but not C-mechanosensitive nociceptors) that may cause dysesthesias/paresthesia suffered by DPNP patients, (b) membrane hyperpolarization and a ∼85% reduction in SA rate in Aβ-LTMs by K7 channel activation with retigabine (6 mg/kg, i.v.) suggesting that K7/M channels may be involved in mechanisms of SA generation in Aβ-LTMs, (c) decreases in AP duration and in duration and amplitude of afterhyperpolarization (AHP) in C-and/or Aβ-nociceptors. …”
Get full text
Get full text

Effects of a single dose of ivermectin on viral and clinical outcomes in asymptomatic sars-cov-2 infected subjects: A pilot clinical trial in lebanon by Samaha, Ali A.

“…Objective: This study was designed to determine the efficacy of ivermectin, an FDA-approved drug, in producing clinical benefits and decreasing the viral load of SARS-CoV-2 among asymptomatic subjects that tested positive for this virus in Lebanon. …”
Get full text
Get full text

Global, regional, and national burden of household air pollution, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 by Fiona B, Bennitt

“…We first estimated the mean fuel type-specific concentrations (in μg/m3) of fine particulate matter (PM2·5) pollution to which individuals using solid fuels for cooking were exposed, categorised by fuel type, location, year, age, and sex. …”
Get full text
Get full text
Get full text

Effects of supervisor’s personality on the support, abuse, and feedback provided to junior accountants by Saadullah, Shahriar M.

Get full text
Get full text
Get full text

Kv7 Channel Activators Flupirtine and ML213 Alleviate Neuropathic Pain Behavior in the Streptozotocin Rat Model of Diabetic Neuropathy by Ahmed, Ashraf Ibrahim

“…Results: STZ rats exhibited behavioral signs of mechanical and heat hypersensitivity as indicated by significant decreases in the mean paw withdrawal threshold (PWT) and mean paw withdrawal latency (PWL), respectively, at 35 days post-STZ treatment. …”
Get full text
Get full text
Get full text

Development of CuAg/Cu2O nanoparticles on carbon nitride surface for methanol oxidation and selective conversion of carbon dioxide into formate by Nazir, Roshan

Get full text
Get full text

Effect Of Sand Blasting On Soda Lime Glass Properties by Bousbaa, C.

“…The as received glass Weibull plot shows a large dispersion expressed by a low Weibull modulus (m = 5.41) and a relatively higher average strength value (smoy = 76 MPa). …”
Get full text

Towards a Comprehensive Study of Fatigue Deducing Techniques for Evaluating the Quality of Experience of Haptic-Visual Applications by Alja'afreh M.

“…With the advancement of cellular communications and the achievement of 5th Generation (5G) mobile networks, a new class of multimedia systems, refereed to as the Tactile Internet, is becoming more prominent. …”
Get full text
Get full text

Global patterns and predictions of seafloor biomass using random forests by Wei, C.-L.

Get full text
Get full text

Pharmacologic inhibition of hypoxia-inducible factor (HIF)-hydroxylases ameliorates allergic contact dermatitis by Manresa M.C.

Get full text
Get full text

Corrosion behavior of API X100 steel material in a hydrogen sulfide environment by Okonkwo, Paul C.

Get full text
Get full text

Enhanced Filtration Characteristics and Reduced Bacterial Attachment for Reverse Osmosis Membranes Modified by a Facile Method by Nnadiekwe, Chidera C.

Get full text
Get full text
Get full text

Clinical significance of P-class pumps in cancer (Review) by Themistocleous, Sophia C.

Get full text
Get full text
Get full text

Effects of Turbulence Intensity and Biogas Composition on the Localized Forced Ignition of Turbulent Mixing Layers by d’Auzay, C. Turquand

Get full text
Get full text

A Reduction in Maximal Incremental Exercise Test Duration 48 h Post Downhill Run Is Associated with Muscle Damage Derived Exercise Induced Pain. by Chrismas, Bryna C R

Get full text
Get full text

Radiofrequency Ablation Versus Antiarrhythmic Drug Therapy for Atrial Fibrillation: Meta-analysis of Safety and Efficacy by Yi F.

“…Random effect summary estimates were calculated as standardized mean differences and odds ratios with 95% confidence intervals for continuous and binary outcomes. …”
Get full text
Get full text

Assessment of Dapagliflozin Effectiveness as Add-on Therapy for the Treatment of Type 2 Diabetes Mellitus in a Qatari Population by Al AdAwi R.M.

“…Administration of dapagliflozin as an add-on therapy was found to decrease HbA1c significantly by 0.8 percentage point after 6 months (P = 0.006) and by 1.5 percentage point after 12 months (P = 0.062). …”
Get full text
Get full text

Limiting the Rise in Core Temperature During a Rugby Sevens Warm-up With an Ice Vest. by Taylor, Lee

“…Athletes in VEST had a lower ΔTc [mean (SD) VEST 1.3°C (0.1°C); CONTROL 2.0°C (0.2°C)] from pre-warm-up to post-warm-up [effect size (ES) ± 90% confidence limit; -1.54; ±0.62] and Tc peak [mean (SD) VEST 37.8°C (0.3°C); CONTROL 38.5°C (0.3°C)] at the end of the warm-up (-1.59; ±0.64) compared to CONTROL. …”
Get full text
Get full text