Decreased early CD4+ and CD8+ T cell expression of TNFα in the lungs and spleens of IFNγ-KO mice infected with the epidemic strain <i>M. massiliense</i> CRM-0019. by Shaobin Shang (205922)

“…Panels B and C show decreased CD4+ and CD8+ T cell expression of TNFα in the lungs (A) and spleens (B) of mice infected with the epidemic strain CRM-0019 compared to CIP 108297 (± SEM, n = 5). …”

The decrease in T cell transduction efficiency by SIV_MAC is not explained by differences in reporter gene expression. by Massimo Pizzato (126906)

NEC survival and intestinal injury. by Joshua S. O’Connell (11785683)

Intestinal proliferation and regeneration. by Joshua S. O’Connell (11785683)

Arid3b^-/- B cells produce normal serum IgG and have no defect in response to LPS during ex vivo culture. by Jeffrey L. Kurkewich (3044211)

The enhancer of <i>Furin</i> M10 is repressed by NKX2-5. by Laurent Dupays (2940330)

“…(C) Electrophoretic mobility shift assay (EMSA) showing that NKX2-5 binds its motif (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0212992#sec002" target="_blank">methods</a>) in the M10 probe (black arrowhead). …”

Anti-Inflammatory Salicin Derivatives from the Barks of <i>Salix tetrasperma</i> by Pei-Qian Wu (12422384)

“…Compounds <b>4</b>–<b>6</b> significantly inhibited NO production in lipopolysaccharide (LPS)-induced RAW 264.7 macrophages, and the most active <b>4</b> obviously suppressed the production of IL-1β and IL-6 and decreased iNOS and COX-2 expression in a dose-dependent manner. …”

Supplementary Material for: Novel digenic variants in COL4A4 and COL4A5 causing X-linked Alport Syndrome by Uedono H. (10917012)

“…The number of cases of digenic AS has increased, but the genotype-phenotype correlation of patient with digenic AS is still unclear. Here, we present a case of digenic AS with novel digenic missense variants in COL4A4 (c.827G>C, p.Gly276Ala) and COL4A5 (c.4369G>C, p.Gly1457Arg). …”

Top 5 drug candidates for DDLB that showed the strongest binding affinity to the non-native structure and weaker affinity to the native structure. by Yang Jiang (46459)

Top 5 drugs for CAT-III that showed the strongest binding affinity to the non-native structure and no binding affinity to the native structure. by Yang Jiang (46459)

Targeted DNA demethylation in human cells by fusion of a plant 5-methylcytosine DNA glycosylase to a sequence-specific DNA binding domain by Jara Teresa Parrilla-Doblas (3825424)

“…In contrast, plants use specific DNA glycosylases that directly excise 5mC and initiate its substitution for unmethylated C in a base excision repair process. …”

OCA-treatment increases the splenic proliferative/activate Treg cells and decreased the apoptotic Treg cells among primary CD4⁺CD25⁺ splenocytes of NASH mice. by Szu-Yu Liu (14241673)

“…<p>IF-based assessments of (<b>A</b>) Foxp3⁺Ki-67⁺ (orange color), (<b>B</b>) Foxp3⁺HLADR⁺ (orange color), (<b>C</b>) TUNEL⁺ (green color) (<b>D</b>) Annexin-5⁺Pi⁺ (green color) cells among primary CD4⁺CD25⁺ Treg cells from Ctrl, Ctrl-OCA, or NASH, NASH-OCA mice. …”

Supplementary Material for: IFNγ-Inducible Chemokines Decrease upon Selenomethionine Supplementation in Women with Euthyroid Autoimmune Thyroiditis: Comparison between Two Doses of... by Pilli T. (4156702)

Immunometabolic remodeling is associated with proinflammatory eicosanoid signaling. by Jeffrey M. Collins (5753942)

Fig 5 - by Wenqi Zhang (2953815)

NREM 1/f slopes calculated from Power Spectrum Densities (PSDs) have a robust nocturnal rhythm at low frequencies that are initially flattened during spontaneous oxycodone withdraw... by Michael Gulledge (20577135)

H + D₂ Reaction Dynamics in the Limit of Low Product Recoil Energy by J. Aldegunde (1373448)

“…Both experiment and theory recently showed that the H + D₂(<i>v</i> = 0, <i>j</i> = 0) → HD­(<i>v</i>′ = 4, <i>j</i>′) + D reactions at a collision energy of 1.97 eV display a seemingly anomalous HD product angular distribution that moves in the backward direction as the value of <i>j</i>′ increases and the corresponding energy available for product recoil decreases. …”

Essential oil from <i>C</i>. <i>obtusa</i> reduces adult lifespan of fruit flies. by Shin-Hae Lee (832213)

Synaptic recruitment of α5-GABA_ARs contributes to wake-dependent enhancement of iLTP. by Kunwei Wu (725668)

“…(B) Representative mIPSC traces and average mIPSC traces at indicated time points in (A) from the CA1 pyramidal neuron in acute hippocampal slices prepared from sleep and wake mice. a+b indicated peak-scaled overlays showing the difference of decay time constants between time points a and b. b+c indicated peak-scaled overlays showing the difference of decay time constants between time points b and c. …”

In vivo assessment of 5-HT_1A and 5-HT₂ post-synaptic receptor function using 8-OH-DPAT-induced change of corticosterone levels and DOI-induced head-twitches. by Thibault Renoir (348572)

“…<p>Compared to paired-saline injected animals, administration of the 5-HT_1A agonist 8-OH-DPAT (0.3 mg/kg, s.c.) significantly increased corticosterone levels in both (A) male and (B) female mice, regardless of the genotype. …”