PSG-specific <i>Fzr</i> mutation decreases the expression of silk protein genes. by Wenliang Qian (639395)

“…(<b>B-D</b>) <i>Fzr</i> mutation in the PSG decreased the transcription of silk protein genes, including <i>FibH</i> (B), <i>FibL</i> (C), and <i>P25</i> (D). …”

WT1 siRNA decreases proliferation, pAKT, and Bcl2 expression. by Ayana E. Morales (17756335)

“…<b>C.</b> RT-qPCR of WT1, p<0.05(*), vFLIP(ns), LANA, p<0.0001(****), K8.1, p<0.0001(****), and BCL2 p<0.05(*) in the setting of WT1 knockdown in ISLK BAC-16 with WT1 siRNA in comparison to a control siRNA using two-sided, unpaired student’s t-tests. …”

Prolonged exposure to oxidized LDL particles decreases Cx36 levels in β-cells. by Jacques-Antoine Haefliger (134116)

Overexpression of constitutively active Fyn kinase in K562 cells decreases cell growth. by Melissa M. Singh (293682)

Decreased TRAF6 levels are sufficient to impair host control of influenza virus replication. by Carrie M. Rosenberger (42649)

GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age. by Nicole K. Polinski (10947787)

“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”

Brain and liver GCase activity are significantly decreased in heterozygous <i>GBA1</i> D409V KI mice, with varying differences in glucosphingolipid lipids in brain and liver. by Nicole K. Polinski (10947787)

“…<p>(A-B) GCase, (C-D) gluocosylceramide (GlcCer), and (E-F) glucosylsphingosine (GlcSph) levels measured in whole brain homogenate and liver homogenate of C57Bl/6 wild type (WT) and <i>GBA1</i> D409V KI heterozygous (HET) mice at 5 months of age (n = 10/age). …”

Activation, inactivation, and deactivation kinetics differ between Ca_V3.3 WT and variants as well as among the variants. by Yousra El Ghaleb (22075892)

Subjects:

VPA decreases cell proliferation. by Muriel Rhinn (406515)

Proviral load in blood was decreased in HTLV-1 infected CD133+ Hu-mice when vCTCF-BS was deleted. by Ancy Joseph (5634794)

Rapamycin decreases phosphorylation of S6. by Adam L. Hartman (308128)

Reduced expression of Tks5 leads to decreased growth of tumor cells <i>in vitro</i> and <i>in vivo</i>. by Barbara Blouw (715467)

Resveratrol decreased nitrite production. by André Quincozes-Santos (108426)

Expression of WT dyskerin can rescue the expression of <i>LGR5</i>, <i>WLS</i> and <i>FRZB</i>. by Bai-Wei Gu (740949)

Subjects:

Doxorubicin decreased the adiponectin levels. by Luana Amorim Biondo (2576386)

Increasing TPP side chain length decreases melanoma cell viability and clonogenic survival. by Kyle C. Kloepping (9928265)

“…A375 melanoma cells were treated with 0.25 μM, 0.5 μM, or 1.0 μM 5-, 8-, 10-, 12-,14-, or 16-TPP for (C) 24 h and (D) 48 h and analyzed for clonogenic survival (* represents when 12-, 14-, and 16-TPP were significant relative to 5-TPP and 8-TPP; Ψ represents when 10-TPP was significant relative to 5-TPP and 8-TPP; p < 0.05; n = 3 from 2 separate experiments; N = 6). …”

The novel <i>carboxylesterase 1</i> variant c.662A>G may decrease the bioactivation of oseltamivir in humans by Jaeseong Oh (3947381)

“…A novel <i>CES1</i> c.662A>G single nucleotide polymorphism (SNP) was predicted to decrease CES1 enzymatic activity in an <i>in silico</i> analysis. …”

Decreased translation efficiency of DENV reporter constructs by RyDEN. by Youichi Suzuki (407067)

Loss of C9orf72 decreases mTOR activation. by Janet Ugolino (3359054)

“…Knockdown of C9orf72 significantly decreased p-S6K1 levels compared with cells treated with control shRNA (n = 3, *<i>p</i><0.5). …”

Botulinum toxin A (3.5 U/kg) decreases mechanical allodynia induced by IoNC- injury in rats. by Boris Filipović (336089)