Cytidine-phosphate-guanosine oligodeoxynucleotides in combination with CD40 ligand decrease periodontal inflammation and alveolar bone loss in a TLR9-independent manner by Qian Zhao (217607)

“…The silk ligature was tied around the maxillary second molars for 14 days, during which the CpG+CD40L mixture or PBS was injected into palatal gingiva on days 3, 6, and 9. Results: For both WT and TLR9 KO mice, CpG significantly induced B cell proliferation, increased IL-10 mRNA expression and protein secretion of IL-10 but reduced CD1dhiCD5+ B cells population; local injection of CpG+CD40L mixture significantly decreased alveolar bone loss and the number of TRAP-positive cells adjacent to the alveolar bone surface, and significantly increased the gingival mRNA expression of IL-10 and decreased RANKL and IFN-γ mRNA expression. …”

Immunostaining of lungs from a control mouse and a mouse infected with SARS-CoV-2. by Germán Ricardo Magaña-Ávila (18446799)

eNOS phosphorylation increased intracellular ROS generation and decreased cell viability in BH4-depleted cells. by Hu Peng (396074)

“…(B) VEGF-mediated eNOS phosphorylation resulted a significant ROS increase in eNOS overexpressing HEK 293 cells (n = 5 fields, *, <i>p</i> < 0.05). (C) eNOS phosphorylation decreased cellular viability in BH4-depleted cells. …”

Image_5_A single amino acid substitution in the AAA-type ATPase LRD6-6 activates immune responses but decreases grain quality in rice.tif by Junjie Yin (3115497)

The expression of 5-hmC was decreased in ESCC tissues and cell lines. by Xuejiao Shi (1684186)

Global Land Use Change Impacts on Soil Nitrogen Availability and Environmental Losses by Jing Wang (6206297)

“…By compiling a global data set of 1,782 paired observations from 185 publications, we show that land use conversion from natural to managed ecosystems significantly reduced NNM by 7.5% (−11.5, −2.8%) and increased NN by 150% (86, 194%), indicating decreasing N availability while increasing potential N loss through denitrification and nitrate leaching. …”

Photostimulation of DRN 5-HT neurons <i>in vivo</i>. by Guillaume P. Dugué (620333)

Blocking C5L2 decreased C5a-primed neutrophils for ANCA-induced respiratory burst. by Jian Hao (160736)

CHAPb Tg mice show decrease cardiac performance. by Willemijn van Eldik (4662955)

C5aR1 Mediates the Progression of Inflammatory Responses in the Brain of Rats in the Early Stage after Ischemia and Reperfusion by Yunwei Shi (10116568)

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C5aR1 Mediates the Progression of Inflammatory Responses in the Brain of Rats in the Early Stage after Ischemia and Reperfusion by Yunwei Shi (10116568)

Subjects:

C5aR1 Mediates the Progression of Inflammatory Responses in the Brain of Rats in the Early Stage after Ischemia and Reperfusion by Yunwei Shi (10116568)

Subjects:

C5aR1 Mediates the Progression of Inflammatory Responses in the Brain of Rats in the Early Stage after Ischemia and Reperfusion by Yunwei Shi (10116568)

Subjects:

C5aR1 Mediates the Progression of Inflammatory Responses in the Brain of Rats in the Early Stage after Ischemia and Reperfusion by Yunwei Shi (10116568)

Subjects:

Decrease of renal fibrosis during AT1 receptor antagonism. by Anne-Cécile Huby (5653777)

“…Values are are mean±SEM; n = 5, 9 and 13 for wild type and RenTg mice before and after irbesartan, respectively; ** P<0,01 vs WT; ^## P<0,01 vs RenTg. …”

Suppression does not depend on a growth rate decrease. by Laurent Jannière (28755)

Decreased Sho levels in different animal models infected with diverse prion strains. by Joel C. Watts (195735)

“…<p>(<b>A</b>) Western blot analysis of brain homogenates prepared from wt FVB mice (expressing the PrP-A allotype) infected with RML, 22L, Me7, and 301V prions, and B6.I mice (expressing the PrP-B allotype) infected with 87V and 301V prions. …”

Phosphosite mutations in Hcm1 decrease fitness in stress. by Michelle M. Conti (13514386)

The differences between 8-week-old K14-VEGF mice and WT mice. by Xuguo Wang (839264)

Receptor for advanced glycation end-products and World Trade Center particulate induced lung function loss: A case-cohort study and murine model of acute particulate exposure - Fig... by Erin J. Caraher (4445902)