Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies حسب Fawaz E., Alanazi

"…Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies حسب Fawaz E., Alanazi

"…Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region حسب Dagenais, Renée

"…A secondary search identified studies reporting genotypic and allelic frequencies of assessed genetic polymorphisms within the Middle East and North Africa region. Results Five studies met the inclusion criteria. CYP2C9, CYP2C19, and multidrug resistance protein 1 C3435T variants were evaluated. …"
احصل على النص الكامل
احصل على النص الكامل

Effect of electroless bath composition on the mechanical, chemical, and electrochemical properties of new NiP-C 3 N 4 nanocomposite coatings حسب Fayyad E.M.

"…An electroless bath of 0.5 g L−1 C3N4 offered a nanocomposite coating with the highest microhardness and superior corrosion resistance. …"
احصل على النص الكامل
احصل على النص الكامل

Enhanced performance of nano-sized SiC reinforced Al metal matrix nanocomposites synthesized through microwave sintering and hot extrusion techniques حسب Reddy, M. Penchal

"…In the present study, nano-sized SiC (0, 0.3, 0.5, 1.0 and 1.5 vol%) reinforced aluminum (Al) metal matrix composites were fabricated by microwave sintering and hot extrusion techniques. …"
احصل على النص الكامل
احصل على النص الكامل

Functional characterization of human myosin-binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon-specific cardiac phenotypes in zebrafish model حسب Da'as, Sahar I.

"…We investigated the impact of two novel human MYBPC3 splice-site variants: V1: c.654+2_654+4dupTGG targeting exon 5 using morpholino MOe5i5; and V2: c.772+1G'A targeting exon 6 using MOe6i6; located within C1 domain of cMyBP-C protein, known to be critical in regulating sarcomere structure and contractility. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Nutritional quality and health risk of pepper fruit as affected by magnesium fertilization. حسب Lu, Ming

"…Compared to control, Mg fertilization increased the 2-year average pepper yield by 25.6%, whereas there was no significant yield improvement when Mg rates exceeded 112.5 kg MgO ha . Magnesium application increased concentrations of Mg and capsaicinoids, decreased those of calcium (Ca), zinc (Zn) and vitamin C (Vc), and had no effect on potassium (K) and iron (Fe) in pepper fruit. …"
احصل على النص الكامل
احصل على النص الكامل

Short-Term Effects of Experimental Warming and Precipitation Manipulation on Soil Microbial Biomass C and N, Community Substrate Utilization Patterns and Community Composition حسب LI, Guanlin

"…Decreased and increased precipitation significantly reduced microbial biomass C by 13.5% and 24.9% and microbial biomass N by 22.9% and 17.6% in unwarmed plots, respectively (P < 0.01). …"
احصل على النص الكامل
احصل على النص الكامل

Reducing energy consumption of CO2 desorption in CO2-loaded aqueous amine solution using Al2O3/HZSM-5 bifunctional catalysts حسب Zhang X.

"…The aim of this work is to find a potential way for great decrease in CO2 capture energy requirement. Here, for the first time, a series of bifunctional Al2O3/HZSM-5 catalysts (Al-ZSM) were prepared by the combined precipitation ultrasound method and used for the CO2 desorption process. …"
احصل على النص الكامل
احصل على النص الكامل

Work-from-home, electricity, and water: Evidence from COVID-19 in Qatar حسب Bernstein, David H.

احصل على النص الكامل
احصل على النص الكامل

In silico and in vivo models for Qatari-Specific classical homocystinuria as basis for development of novel therapies. حسب Ismail, Hesham M

احصل على النص الكامل
احصل على النص الكامل

Acute mercury toxicity modulates cytochrome P450, soluble epoxide hydrolase and their associated arachidonic acid metabolites in C57Bl/6 mouse heart حسب Amara, Issa E.A.

"…Mercury toxicity was induced by a single intraperitoneal injection (IP) of 2.5mg/kg of mercuric chloride (HgCl2). Our results showed that mercury treatment caused a significant induction of the cardiac hypertrophy markers, atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP); in addition to Cyp1a1, Cyp1b1, Cyp2b9, Cyp2b10, Cyp2b19, Cyp2c29, Cyp2c38, Cyp4a10, Cyp4a12, Cyp4a14, Cyp4f13, Cyp4f15, Cyp4f16 and Cyp4f18 gene expression. …"
احصل على النص الكامل
احصل على النص الكامل

Cutaneous Aβ-Non-nociceptive, but Not C-Nociceptive, Dorsal Root Ganglion Neurons Exhibit Spontaneous Activity in the Streptozotocin Rat Model of Painful Diabetic Neuropathy . حسب Djouhri, Laiche

"…Compared with control, we found in STZ-rats with established pain hypersensitivity (5 weeks post-STZ) several significant changes including: (a) A 23% increase in the incidence of spontaneous activity (SA) in Aβ-LTMs (but not C-mechanosensitive nociceptors) that may cause dysesthesias/paresthesia suffered by DPNP patients, (b) membrane hyperpolarization and a ∼85% reduction in SA rate in Aβ-LTMs by K7 channel activation with retigabine (6 mg/kg, i.v.) suggesting that K7/M channels may be involved in mechanisms of SA generation in Aβ-LTMs, (c) decreases in AP duration and in duration and amplitude of afterhyperpolarization (AHP) in C-and/or Aβ-nociceptors. …"
احصل على النص الكامل
احصل على النص الكامل

Effects of supervisor’s personality on the support, abuse, and feedback provided to junior accountants حسب Saadullah, Shahriar M.

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Development of CuAg/Cu2O nanoparticles on carbon nitride surface for methanol oxidation and selective conversion of carbon dioxide into formate حسب Nazir, Roshan

احصل على النص الكامل
احصل على النص الكامل

Effect Of Sand Blasting On Soda Lime Glass Properties حسب Bousbaa, C.

احصل على النص الكامل

Global patterns and predictions of seafloor biomass using random forests حسب Wei, C.-L.

احصل على النص الكامل
احصل على النص الكامل

Pharmacologic inhibition of hypoxia-inducible factor (HIF)-hydroxylases ameliorates allergic contact dermatitis حسب Manresa M.C.

احصل على النص الكامل
احصل على النص الكامل

Corrosion behavior of API X100 steel material in a hydrogen sulfide environment حسب Okonkwo, Paul C.

احصل على النص الكامل
احصل على النص الكامل

Enhanced Filtration Characteristics and Reduced Bacterial Attachment for Reverse Osmosis Membranes Modified by a Facile Method حسب Nnadiekwe, Chidera C.

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل