Young (3 months) or old (18 months) WT and smcKlf5^−/− mice were infused with Ang II for 28 days. by Dong Ma (584680)

Subjects:

Klf5 down-regulation leads to human VSMC senescence. by Dong Ma (584680)

Subjects:

Chronic high glucose induces apoptosis and proteasome activities decrease in INS-1E cells. by Christophe Broca (538652)

The influence of 5-HT on MSQ43 cells. by Li Gao (131516)

Additional Analysis of visually induced calcium transients in Fig 5. by Maureen M. Sampson (9322886)

“…(<b>A</b>) The change in the secondary response (the magnitude of the calcium decrease following the initial peak). (<b>B</b>) Change in the exponential time constant k (units 1/sec) relative to epoch 1 (defined by ΔF/F(t) = c<i>e</i>^kt) for the time between 10% and 90% of the post-stimulus peak-to-peak difference in ΔF/F. …”

Silencing of RCC1L isoforms alter the levels of mitochondrial ribosomal proteins and biogenesis factors resulting in decreased mitochondrial translation. by Aurelio Reyes (412135)

FTY720 decreased viability, proliferation, and motility and induced apoptosis in human hepatoblastoma cells. by Laura L. Stafman (6577184)

“…(B) Following 24 hours of treatment with FTY720, the proliferation of HuH6 cells measured using the CellTiter 96 cell proliferation assay was significantly decreased (IC₅₀ = 6.4 μM, p ≤ 0.05). (C) HuH6 cells were plated and allowed to reach 80% confluence, at which time the media was changed for fresh media (0, 5, or 8 μM FTY720) and a standard scratch wound was made. …”

<i>Ubr5</i>^<i>mt</i> synovium exhibits markers of increased canonical and decreased non-canonical HH signalling. by David Mellis (2833469)

Repetitive stress induces a decrease in sound-evoked activity. by Ghattas Bisharat (20706928)

“…Activity rates decreased during repeated stress compared to baseline (2-way ANOVA, condition F = 185.6, <i>p</i> = 4.8 × 10⁻⁴², condition: intensity interaction F = 10.37, <i>p</i> = 9.3 × 10⁻²¹, nested ANOVA (mouse nested within session), condition F = 174, <i>p</i> = 1.5 × 10⁻³⁹, condition: intensity interaction F = 12.7, <i>p</i> = 2 × 10⁻²⁶, post hoc for each level baseline versus repetitive stress <i>p</i> < 0.01 for all levels above 50 dB, all Bonferroni corrected). …”

Knockdown of MRN complex decreases HBV cccDNA level. by Kaitao Zhao (3617825)

Knockdown of MRN complex decreases HBV cccDNA level. by Kaitao Zhao (3617825)

Juvenile demyelination leads to a substantial decrease in potassium currents in PV interneurons of the PFC. by Sara Hijazi (21656615)

“…Scale: 500 pA, 100 ms. <b>B</b>. I–V curves showing a significant decrease in Kv amplitude in PV interneurons from mice that underwent juvenile demyelination. …”

Antagonist dosage and occupancy for each 5-HT receptor subtype. by Yukiko Hori (299784)

Subjects:

HPD 1466 decreases empty capsid accumulation in cells replicating HBV. by Daniel P. Bradley (10306893)

The LCS stream is absent in E16.5 <i>Emx1</i>-cKO mice. by Sathish Venkataramanappa (10331993)

GSK343 decreased tumor stemness. by Laura V. Bownes (10276762)

“…Treatment with GSK343 significantly decreased tumorsphere formation by both the COA3 (A) and COA6 (B) cells, representing a decrease in stem cell-like phenotype. …”

Characteristics of patients with AKI diagnosed using KDIGO definition versus patients diagnosed with AKI by eKDIGO only by the decrease in sCr (deKDIGO). by Marina Wainstein (12437091)

Additional Analysis of visually induced calcium transients in Fig 6. by Maureen M. Sampson (9322886)

“…<p>Visually induced calcium transients were recorded in 5-HT2B +/- or 5-HT2B -/- flies as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009003#pgen.1009003.g006" target="_blank">Fig 6</a>. …”

Serotonin modulates L2 neuron visually induced calcium transient kinetics. by Maureen M. Sampson (9322886)

“…Color coded traces representing each 60 s epoch for saline (left panel, cyan to blue) and serotonin (right panel, yellow to red) are shown. (<b>E-E’</b>) Analysis of light flash response from panel D. …”

SARS-CoV-2 induced lung inflammation is increased with IL-10 blockade and decreased with IFNγ blockade. by Christine E. Nelson (18946410)