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Exposure to low CO<sub>2</sub> levels decreases ER cholesterol levels.
Published 2023“…<b>(D, E)</b> The free cholesterol and cholesterol ester levels in the ER membrane from the cells as in <b>(C)</b>, were quantified with shotgun lipidomics analysis (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s007" target="_blank">S7 Fig</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s012" target="_blank">S5 Table</a>) (mean ± SE, <i>n</i> = 3 independent experiments, **<i>P</i> < 0.01, *<i>P</i> < 0.05, nonsignificant (ns) two-sided Student’s <i>t</i> test). …”
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Cinacalcet administered early in the inactive phase markedly decrease parathyroid Ki-67 index.
Published 2025“…(B) For each group, the median Ki-67 immunostained parathyroid sample closest to the group mean is shown. Each dot represents one sample. Scale bars measures 50μm.…”
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Increased osteoblastic activity and decreased osteoclastogenesis in TgLRAP cells <i>in vitro</i>.
Published 2021“…Compared with the co-culture of WT BMCs and WT calvarial cells (WT / WT), the number of osteoclasts were significantly decreased at 50% in the co-cultures of TgLRAP BMCs and TgLRAP calvarial cells (TgLRAP / TgLRAP) (graph). …”
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Decreased ISCs and increased goblet cells after intestinal specific loss of MLL1.
Published 2021“…(C) Decrease in ISC markers, OLFM4 and SOX9 in <i>Mll1</i><sup><i>FC/FC; Vil-Cre-ERT2/+</i></sup> intestinal sections. …”
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5-HT2A and Foxo are required in R2/R4 neurons to mediate the effects of death perception on lifespan.
Published 2023“…<p>Knock-down of <i>5-HT2A</i> mRNA expression in R2 alone (A), in R4d alone (B), or in R2/R4 inhibited lifespan differences due to death perception. …”
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Plot of mean vigor by group and time.
Published 2024“…There was a general trend towards increases in CS in the Heartfulness group compared to the gratitude group. …”
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Plot of mean Burnout by group and time.
Published 2024“…There was a general trend towards increases in CS in the Heartfulness group compared to the gratitude group. …”
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