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fold decrease » fold increase (Expand Search), fold increased (Expand Search)
ns decrease » nn decrease (Expand Search), _ decrease (Expand Search), we decrease (Expand Search)
ng decrease » nn decrease (Expand Search), _ decrease (Expand Search), we decrease (Expand Search)
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5 ng » 5 mg (Expand Search), 5 g (Expand Search), 5 nm (Expand Search)
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Exposure to low CO<sub>2</sub> levels decreases ER cholesterol levels.
Published 2023“…<b>(C)</b> Total cholesterol quantification (with fluorometric assay kit) in NIH3T3 cells depleted with sterols for 2 h or exposed to different CO<sub>2</sub> levels for 4 h (mean ± SE, <i>n</i> = 3 biological replicates per condition, **<i>P</i> < 0.01, nonsignificant (ns), two-sided Student’s <i>t</i> test). <b>(D, E)</b> The free cholesterol and cholesterol ester levels in the ER membrane from the cells as in <b>(C)</b>, were quantified with shotgun lipidomics analysis (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s007" target="_blank">S7 Fig</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002367#pbio.3002367.s012" target="_blank">S5 Table</a>) (mean ± SE, <i>n</i> = 3 independent experiments, **<i>P</i> < 0.01, *<i>P</i> < 0.05, nonsignificant (ns) two-sided Student’s <i>t</i> test). …”
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Discovery of New Inhibitors of Hepatitis C Virus NS3/4A Protease and Its D168A Mutant
Published 2019“…However, in the same assay, the potency of the approved drug, simeprevir, decreased 5.7-fold for the mutant enzyme relative to the wild type. …”
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The <i>rcan-1</i> rearrangement allele decreases expression of <i>rcan-1</i>.
Published 2020“…Cyan: p<0.01, log<sub>2</sub>(Fold Change) < -1. (The list of differential expressed genes with significance are available in <b><a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1008606#pgen.1008606.s018" target="_blank">S5 Table</a></b>). …”
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