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FLCN-deficiency leads to decreased Rho activity in sub-confluent cells and delays in wound closure.
Published 2013“…<b>B)</b> Rho activity was measured using a Rhotekin binding assay at 70% confluence. The FLCN-null UOK257 cells had a 2.5-fold decrease in active Rho levels (Rho GTP) compared to the FLCN re-expressing UOK257-2 cells (n = 3, p<0.05). …”
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Fold change with steady state myocardial mRNA levels for components of the inflammasome.
Published 2024Subjects: -
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Variability and correlations decrease during task states in human fMRI data.
Published 2020“…<p>Figures for the replication cohort are in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1007983#pcbi.1007983.s004" target="_blank">S4 Fig</a>. …”
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Decrease in Vitamin D Status in the Greenlandic Adult Population from 1987–2010
Published 2014“…</p><p>Conclusion</p><p>We identified a remarkable decrease in vitamin D status from 1987 to 2005–2010 and a presently low vitamin D status among Inuit in Greenland. …”
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Zcchc11 deficiency decreases IGF-1 expression <i>in vivo</i>.
Published 2012“…<p>(A) IGF-1 mRNA, measured by qRT-PCR, was decreased by Zcchc11 deficiency in 8-day-old livers. …”
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Discovery of a Colon-Targeted Azo Prodrug of Tofacitinib through the Establishment of Colon-Specific Delivery Systems Constructed by 5‑ASA–PABA–MAC and 5‑ASA–PABA–Diamine for the T...
Published 2022“…Specifically, compound <b>20g</b> displayed a 3.67-fold decrease of plasma AUC<sub>(tofacitinib, 0–∞)</sub> and a 9.61-fold increase of colonic AUC<sub>(tofacitinib, 0–12h)</sub>, compared with tofacitinib at a molar equivalent oral dose. …”
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