Gene-gene interaction network underlying LRO accumulation of Nile red and autofluorescence. by Alexander A. Soukas (476353)

“…Genes were clustered by <i>k</i>-means clustering, with the heatmap indicating genes that increase LRO Nile red in yellow and decrease LRO Nile red in blue. No inference can be made on the absolute magnitude of the effect from the heatmap as data from each mutant for all 79 genes are normalized and scaled (see <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003908#s4" target="_blank">methods</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003908#pgen.1003908.s007" target="_blank">table S3</a> for absolute fold change differences). …”

Image_1_Genome-Wide Expression Analysis of Glyoxalase I Genes Under Hyperosmotic Stress and Existence of a Stress-Responsive Mitochondrial Glyoxalase I Activity in Durum Wheat (Tri... by Mario Soccio (12961406)

“…Accordingly, in the same tissues, hyperosmotic stress induced an increase (up to about 40%) of both GLYI activity and MG content as well as a decrease of GSH (up to about –60%) and an increase of GSSG content (up to about 7-fold) with a consequent strong decrease of the GSH/GSSG ratio (up to about –95%). …”

Data_Sheet_2_Genome-Wide Expression Analysis of Glyoxalase I Genes Under Hyperosmotic Stress and Existence of a Stress-Responsive Mitochondrial Glyoxalase I Activity in Durum Wheat... by Mario Soccio (12961406)

“…Accordingly, in the same tissues, hyperosmotic stress induced an increase (up to about 40%) of both GLYI activity and MG content as well as a decrease of GSH (up to about –60%) and an increase of GSSG content (up to about 7-fold) with a consequent strong decrease of the GSH/GSSG ratio (up to about –95%). …”

Human brain-derived clonal MSC upregulate immature neuronal markers and downregulate pericyte markers upon neuronal induction. by Gesine Paul (326199)

“…(B) At the same time, mRNA expression for pericyte markers Nestin, α-SMA, RGS5 and PDGFR-β decreased compared to undifferentiated controls. …”

CD14 controls LTA and Pam₃CSK₄ internalization and NF-κB activation. by Karim J. Brandt (362950)

“…CD14 blocking antibody decreases significantly TNF production. Data are represented as mean +/- SD of at least 4 independent experiments. …”

Data_Sheet_1_Incidence and outcomes of acute high-risk chest pain diseases during pregnancy and puerperium.PDF by Shengyong Wu (304695)

“…The most frequent was PE (86.5%), followed by AMI (9.6%) and AD (3.3%). The incidence of PE in pregnancy decreased after 2014 and was lower than AMI and AD, while its incidence in puerperium was higher than AMI and AD consistently (P_trend < 0.0001). …”

Colocalized synaptophysin-GFP puncta. by Irina Antonova (369433)

“…An increase in N1 (for example, comparing glutamate to control) corresponds to a rapid increase in sites at 10 min, an increase in P3 corresponds to a gradual increase (or a smaller decrease) from 10 min to 3 hrs, and an increase in N2 corresponds to an increase in stable sites.…”

Predicted mutation selection windows for <i>E</i>. <i>coli</i> exposed to ampicillin. by Fabrizio Clarelli (3622889)

“…The blue line represents the wild-type strain based on the fits shown in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008106#pcbi.1008106.g005" target="_blank">Fig 5</a>, and the red line represents a strain with a theoretical resistance mutation that decreases the binding rate (<i>k</i>_f) 100-fold and imparts a 15% fitness cost. …”

Baseline Goblet Cell Mucin Secretion in the Airways Exceeds Stimulated Secretion over Extended Time Periods, and Is Sensitive to Shear Stress and Intracellular Mucin Stores by Yunxiang Zhu (326362)

“…HBECCs exposed to low perfusion rates exhibited spike-like increases in BLMS when flow was jumped 5-fold: BLMS increased >4 fold, then decreased within 5 min to a stable plateau at 1.5–2-fold over control. …”

NC score, sCr, normalized fold TIMP-2 expression and staining of urinary sediment of representative patient #1. by Daniela Knafl (4234138)

“…Improvement of renal function was accompanied by an increase of urinary sediment TIMP-2 expression, and decrease in NC score parameter. 100 days after kidney transplantation the patient was alive with a serum creatinine of 2.1 mg/dL. …”

Representative images of HBO-treated MSCs. by Jennifer Schulze (2502799)

“…All pictures are presented at a 200-fold magnification. Scale bar: 100 μm.</p>…”

Altered Heart Rates Precede Death. by David S. Auerbach (470466)

“…Heart rates in DS mice decrease 100 min before death, followed by a sharp increase just prior to the terminal event, while the WT heart rates remains high and constant. (100 minutes = 10:16 PM in WT-1 and DS-1; 7:46 PM in WT-2 and DS-2). …”

Technical and economic viability of rendering mortar produced with incorporation of ornamental rocks residue by Luís Gustavo Fiorese Vinco (4653883)

“…In this research, the mixtures that showed the best results were those with an addition of 100% of ORRC. Regarding production costs, there was a decrease in all the mixtures with the addition of ORRC. …”

Supplementary Material for: One-Year Mortality Rates in US Children with End-Stage Renal Disease by Chavers B.M. (3631768)

“…One-year mortality rates showed evidence of a decrease in the number of peritoneal dialysis patients (6.03 per 100 patient-years, 1995; 2.43, 2010; p = 0.0263). …”

Differential gene expression in 17<i>syn</i>⁺-, 17ΔN/H-, m2kb-S-, and 17-37-infected skin <i>in vivo</i>. by Emilia A. H. Vanni (9922652)

“…For any gene, a positive log₂-fold change indicates an increase in the first virus over the other, whereas a negative value indicates a decrease. …”

TAE-684 inhibits signalling downstream of CLTC-ALK in LM1 cells. by Leandro Cerchietti (103837)

“…Data was normalized to RPL13A levels. Data is presented as fold decrease compared to control (DMSO treated cells). …”

Mechanochemical Activation of Silicone for Large-Scale Fabrication of Anti-Biofouling Liquid-like Surfaces by Nusret Celik (6033221)

“…For example, PDMS-grafted surfaces prepared on a regular-size toilet bowl exhibit a 10⁵-fold decrease in the attachment of bacteria from urine. …”

Marimastat reduces necroinflammatory injury following a single dose of carbon tetrachloride (CCl4) via a TNF-dependent pathway. by Vincent E. de Meijer (343377)

“…Serum ALT levels in TNF p55−/− p75−/− animals were 5-fold lower compared to wild type controls, corroborating the findings on histology and indicating decreased hepatic injury in animals lacking both TNF-receptors (F). …”

NKT-deficient Jα18 KO mice () were primed with ovalbumin and alum as in our standard protocol in Materials and methods by Lei Fang (46620)

“…(B and C) Cytokine and TL1A mRNA expression in bronchial lymph nodes (LN; B) and lung parenchyma (C) determined by real time Taqman PCR. The fold increase or decrease of mRNA in Jα18 KO mice (Jα) adoptively transferred with WT NKT cells over mice adoptively transferred with DN TNFR25-tg NKT (DN NKT) cells is plotted.…”

Image_2_Comparison of the extracellular vesicle proteome between glaucoma and non-glaucoma trabecular meshwork cells.tif by Fiona S. McDonnell (17106334)

“…</p>Results<p>Results showed changes in the percentage of ECM proteins associated with EVs from glaucomatous TM cells compared to non-glaucomatous TM cells (5.7% vs 13.1% respectively). Correspondingly, we found that two ECM-related cargo proteins found across all samples, fibronectin and EDIL3 were significantly less abundant in glaucomatous EVs (<0.3 fold change across all groups) compared to non-glaucomatous EVs. …”