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FLCN-deficiency leads to decreased Rho activity in sub-confluent cells and delays in wound closure.
Published 2013“…<b>B)</b> Rho activity was measured using a Rhotekin binding assay at 70% confluence. The FLCN-null UOK257 cells had a 2.5-fold decrease in active Rho levels (Rho GTP) compared to the FLCN re-expressing UOK257-2 cells (n = 3, p<0.05). …”
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Zcchc11 deficiency decreases IGF-1 expression <i>in vivo</i>.
Published 2012“…<p>(A) IGF-1 mRNA, measured by qRT-PCR, was decreased by Zcchc11 deficiency in 8-day-old livers. …”
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Dox-inducible expression of HA-MAD1 in colon is sufficient to decrease p53 expression and cause chromosome missegregation.
Published 2024“…Colors indicate samples from different animals. Large circles show mean of cells from 5 fields of view from a single animal. …”
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Viral loads of CrPV and DCV across host species during single and coinfection.
Published 2023Subjects: