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65341
Image_4_The Valproate Mediates Radio-Bidirectional Regulation Through RFWD3-Dependent Ubiquitination on Rad51.tif
Published 2021“…Here, using the 7,12-dimethylbenz[α]anthracene (DMBA)-induced malignant transformed MCF10A cells, we found that valproate (VPA), a histone deacetylase inhibitor (HDACi), radiosensitized transformed cells while alleviated IR-induced damage in normal cells at a safe dose (0.5 mM). …”
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65342
Data_Sheet_3_Network Modeling of Liver Metabolism to Predict Plasma Metabolite Changes During Short-Term Fasting in the Laboratory Rat.ZIP
Published 2019“…We then measured plasma metabolite profiles in rats fasted for 5–7 or 10–13 h to test our model predictions. Our computational model accounted for two-thirds of the observed directions of change (an increase or decrease) in plasma metabolites, indicating their origin in the liver. …”
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65343
DataSheet_2_Natal environmental conditions modulate senescence of antler length in roe deer.csv
Published 2023“…We found evidence of similar patterns of antler length senescence in both populations, with an onset of senescence around 7 years of age and a decrease of length by about 1–1.5 cm per additional year of life from 7 years of age onwards. …”
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65344
Table_1_PUB11-Dependent Ubiquitination of the Phospholipid Flippase ALA10 Modifies ALA10 Localization and Affects the Pool of Linolenic Phosphatidylcholine.xlsx
Published 2020“…In Arabidopsis, ALA10, a phospholipid flippase of the P<sub>4</sub> type-ATPase family, counteracts the limitation of monogalactosyldiacylglycerol (MGDG) production and has a positive effect on leaf development. …”
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65345
Neutral Gold Complexes with Tridentate <i>SNS</i> Thiosemicarbazide Ligands
Published 2016“…On the other hand, the reduction of Au<sup>III</sup> to Au<sup>I</sup> leads to a considerable decrease of the cytotoxicity.…”
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65346
Induction of apoptosis by pinostrobin in human cervical cancer cells: Possible mechanism of action
Published 2018“…Additionally, a significant increase in the expression of proteins of extrinsic (TRAIL R1/DR4, TRAIL R2/DR5, TNF RI/TNFRSF1A, FADD, Fas/TNFRSF6) and intrinsic pathway (Bad, Bax, HTRA2/Omi, SMAC/Diablo, cytochrome C, Pro-Caspase-3, Cleaved Caspase-3) was observed in the cells exposed to P<sub>N</sub>. …”
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65347
Image_2_Network Modeling of Liver Metabolism to Predict Plasma Metabolite Changes During Short-Term Fasting in the Laboratory Rat.tif
Published 2019“…We then measured plasma metabolite profiles in rats fasted for 5–7 or 10–13 h to test our model predictions. Our computational model accounted for two-thirds of the observed directions of change (an increase or decrease) in plasma metabolites, indicating their origin in the liver. …”
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65348
Table_3_Deciphering the influence of dietary synbiotics in white shrimp gut and its effects in regulating immune signaling pathways.doc
Published 2025“…The diet containing L. acidophilus at 1 × 10<sup>7</sup> CFU/g and M. oleifera at 2.5 g/kg led to an increase in the relative abundance of beneficial microorganisms through a significant decrease in the α diversity. …”
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65349
Synthesis and Biological Evaluation of New Chalcogen Semicarbazone (<i>S</i>, <i>Se</i>) and Their Azole Derivatives against Chagas Disease
Published 2024“…Seleno-compounds demonstrated enhanced activity and selenazoles showed a decrease in selenium-associated toxicity. Compound 4-methyl-2-(2-(1-(3-nitrophenyl)ethylidene)hydrazineyl)-1,3-selenazole (<i><b>Se</b></i><b>2h</b>) emerged as a promising candidate, and its binding to cruzain was investigated. …”
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65350
Supplementary Material for: Population-Attributable Risk Fractions for Antiplatelets and Anticoagulants in Spontaneous Intracranial Hemorrhages
Published 2023“…<b><i>Methods:</i></b> From the National Health Insurance Service-National Sample Cohort including 1,108,369 citizens, 4,385 cases, aged 20 years or more and newly diagnosed as sICHs between 2003 and 2015, were included in this study. A total of 65,775 sICH-free controls were randomly selected at a ratio of 1:15 from individuals with the same birth year and sex according to a nested case-control study design. …”
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65351
Large-Scale Spatio-Temporal Patterns of Mediterranean Cephalopod Diversity
Published 2016“…While the western basin showed a high diversity, our analyses do not support a steady eastward decrease of diversity as proposed in some previous studies. …”
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65352
Table_2_Network Modeling of Liver Metabolism to Predict Plasma Metabolite Changes During Short-Term Fasting in the Laboratory Rat.XLSX
Published 2019“…We then measured plasma metabolite profiles in rats fasted for 5–7 or 10–13 h to test our model predictions. Our computational model accounted for two-thirds of the observed directions of change (an increase or decrease) in plasma metabolites, indicating their origin in the liver. …”
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65353
Metformin treatment inhibited the expression of 4EBP1 and S6K1.
Published 2017“…<p><b>A</b>. KYSE 450 cells were treated with 5, 10, 20 mmol/L of metformin for 48h. …”
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65354
Grüter et al. (2022) PLOS ONE "Expected global suitability..."
Published 2021“…Per crop, four raster maps (.tif raster format) are available:</div><div>The crops' overall current suitability (crop_current.tif), the current climate suitability (crop_climate.tif) based on climate parameters only, the current land and soil suitability (crop_soil.tif) based on land and soil parameters only and the suitability change by 2050 due to climate change according to RCP4.5.</div><div>For the former three maps (crop_current.tif, crop_climate.tif, crop_soil.tif), each raster cell contains a value between 1 to 4 which represent decreasing crop suitability (1: S1 very suitable; 2: S2 moderately suitable; 3: S3 marginally suitable; 4: N unsuitable).…”
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65355
Table_1_No association between incidence of type 1 diabetes and rotavirus vaccination in Swedish children.docx
Published 2023“…Background<p>Rotavirus infection is a potential trigger of type 1 diabetes (T1D) and rotavirus vaccination is hypothesized to decrease the incidence of T1D. …”
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65356
Heat map grid summarizing the effects of LPS and BET inhibitors on target gene mRNA expression in DSCs.
Published 2023“…The significance threshold is 5% FDR (Q<0.05), highlighted in bold. The orange color indicates a significant increase, the blue color indicates a significant decrease regarding the contrasts shown. …”
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65357
DataSheet_1_Natal environmental conditions modulate senescence of antler length in roe deer.csv
Published 2023“…We found evidence of similar patterns of antler length senescence in both populations, with an onset of senescence around 7 years of age and a decrease of length by about 1–1.5 cm per additional year of life from 7 years of age onwards. …”
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65358
Sensitivity of retinal endothelial cells by FP59 and LeTx <i>in vitro</i> and <i>in vivo</i>.
Published 2009“…Immunoblots indicate cleavage of MEK1 following LeTx treatment via loss of N-terminal epitope (MEK1 NT), as well as a decrease in phosphorylated ERK (pERK). (D) <i>In vivo</i> analysis of retinal vasculature following intravitreal injection of FP59 and PA (0.02 µg FP59 and 0.1 µg PA in 1 µL) of postnatal day 10 (PN10) and PN21 C57BL/6 mice. …”
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65359
New diagnostic index for sarcopenia in patients with cardiovascular diseases
Published 2017“…Sarcopenia is diagnosed by a decrease in skeletal muscle index (SMI) and reduction of either handgrip strength or gait speed. …”
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65360
Data_Sheet_1_The Effects of Food Taxes and Subsidies on Promoting Healthier Diets in Iranian Households.docx
Published 2022“…</p>Methods<p>This study was performed in two phases. In phase one, a two-round Delphi study was conducted to determine and prioritize food-related fiscal policies; and in the second phase, using the Iranian Household Income and Expenditure Survey (HIES), we estimated an almost ideal demand system (AIDS) and simulated changes in purchases, nutrient intake, and consumer welfare under six different policy scenarios: (1) 20% subsidy on vegetables, (2) 20% subsidy on fruits, (3) 30% subsidy on legumes, (4) 25% tax on sugar and sweets, (5) 30% tax on sweetened beverages, and (6) 30% tax on hydrogenated oil and animal fats.…”