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Lithium Decreases Glial Fibrillary Acidic Protein in a Mouse Model of Alexander Disease
Published 2015“…Here we tested whether lithium treatment would decrease levels of GFAP in a mouse model of Alexander disease. …”
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Genes correlated with SARS-CoV-2 viral load over time are similarly expressed in independent datasets of SARS-CoV-2 infected lung and upper airway cells.
Published 2025“…<p><b>(a)</b> Differential expression patterns for the 112 genes correlated with SARS-CoV-2 viral load across our serial sampling cohort (p<0.001, from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0317033#pone.0317033.g003" target="_blank">Fig 3A</a>) were examined in two independent RNA-seq datasets of SARS-CoV-2 infection: one of lung cancer cell lines (A549 and Calu-3) infected with SARS-CoV-2 at multiplicity-of-Infection (MOI) of 2 for 24 hours (in biological triplicate)[<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0317033#pone.0317033.ref028" target="_blank">28</a>], and one of nasopharyngeal/oropharyngeal samples in 238 patients with COVID-19, other viral, or non-viral acute respiratory illnesses [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0317033#pone.0317033.ref029" target="_blank">29</a>]. …”
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P<i><sub>TET</sub></i>-driven OE of 20 genes results in decreased or increased growth rate. A. Impact of OE on the growth rates of 257 OE strains.
Published 2012“…Genes in orange correspond to those whose OE decreased growth with a fold equal to 2. Data are mean and SD of 3 experiments. …”
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