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point decrease » point increase (Expand Search)
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point decrease » point increase (Expand Search)
fold decrease » fold increase (Expand Search), fold increased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
5 fold » _ fold (Expand Search)
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1101
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1103
The I827K substitution destabilizes the 3D fold of E6AP<sup>C-lobe</sup> (residues 761–875).
Published 2020“…<p>(A) The assigned <sup>1</sup>H-<sup>15</sup>N-HSQC spectrum of 3.5 mM human E6AP catalytic C-lobe (residues 761–875) using the one-letter amino acid code and residue number according to the human E6AP sequence. …”
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1104
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1105
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1106
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1107
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1109
Validation of primary screen hits reveals compounds that recapitulate increased spheroid size (swell) or decreased MUC5AC in the lumen.
Published 2023“…Compounds that appeared to cause toxicity were identified by observing a significant decrease in spheroid counts in the swell readout or a significant decrease in the total nuclear intensity of the MUC5AC ratio readout. …”
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1110
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1111
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1112
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1113
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1114
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1115
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1119
Increase of proliferating progenitor cells and decrease of terminally differentiated granule neurons in the immature dentate gyrus of <i>PC3/Tis21</i>-null mice at P14.
Published 2009“…(<b>B</b>, <b>C</b>) The same significant increase is observed for the number of dividing progenitor cells, identified either as (<b>B</b>) Ki67-positive, or as (<b>C</b>) Ki67/Sox2-positive cells (1.5-fold). (<b>D</b>) The newly generated neurons (1 hour pulse of BrdU) decreased sharply (20%). …”
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1120