Longitudinal MRI study of changes in BTB permeability and rCBV of brain metastases. by Heling Zhou (368949)

“…All the tumors except one (yellow arrowhead) still kept BTB intact at week 4. rCBV maps were created and rCBV values of the tumors were presented in the table (<b>B</b>). <b>C.</b> A total of 32 lesions in 5 animals were seen on both scans of weeks 3 and 4. rCBV of brain metastases (solid) was initially similar to that of contralateral normal brain (open; mean  = 1.05±0.05 (se) vs. 0.96±0.04), but decreased significantly (p<0.05) and became significantly lower as compared to their contralateral normal brain in the late scan (mean  = 0.88±0.06 vs. 1.00±0.06; p<0.05).…”

Data_Sheet_1_N6-Methyladenine in Eukaryotic DNA: Tissue Distribution, Early Embryo Development, and Neuronal Toxicity.PDF by Sara B. Fernandes (10860612)

“…Furthermore, exposure to a neurotoxic environmental pollutant during the same early life period may led to a decrease in the levels of this modification in female rats. …”

ROP18 directly phosphorylates Irga6 at T102 and T108 in vitro. by Tobias Steinfeldt (154465)

“…<p>(A) Bacterially expressed, purified wt or T102A and T108A mutant Irga6 proteins (300 ng) were coincubated with bacterially expressed, purified GST-ROP18-Ty (10 µl, 5 µl, 1.7 µl respectively; 1 µl ∼20 ng) in the presence of γ³²P-ATP in vitro. …”

Redox Active Cage for the Electrochemical Sensing of Anions by Valeria Amendola (1966936)

“…Such a behavior parallels the gradual decrease of the equilibrium constant for anion inclusion into the [Co^II(<b>1</b>)]⁵⁺ receptor.…”

The TYDQYI-motif in the SBD of PauR is essential for the overall functionality of the receptor and DAR-sensing. by Sophie Brameyer (731567)

“…<p>The most drastic effects on DAR-sensing were gained with the replacement of S38A, T62A, Y66A, D75A and D75N in the SBD of PauR and a decreased effect on DAR-sensing were gained with the replacement of Y90C and I113S in PauR (lower right quadrant). …”

The effects of Hb binding site number and strength on noise. by David M. Holloway (95831)

“…(C) Simulation with 6 Bcd sites and 2 Hb sites, compare to (D) lacZ in a pThb5 embryo (promoter indicated by green arrows in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1001069#pcbi-1001069-g002" target="_blank">Figure 2A</a>). …”

Image analyses of heterodimerization between TASK1 and TALK2. by Yoshiaki Suzuki (7037)

“…<b>(B)</b> FRET analysis based on acceptor photobleaching was carried out using a confocal microscope. YFP within the ROI 1–5 (white rectangles in the figures) in HEK293 cells co-expressing TASK1-YFP+CFP-TALK2 was selectively photobleached using a laser at 514 nm wavelength. …”

Table_1_Bioinformatics Analysis Identifies Potential Ferroptosis Key Genes in the Pathogenesis of Intracerebral Hemorrhage.DOCX by Tongye Liu (10931763)

“…Treadmill training increased the expression of anti-inflammatory molecules TNFAIP3 and SLC2A1 and reduced the expression of MAPK1, ATF4, and MAPK8, indicating that treadmill training may be utilized as antioxidant therapy to decrease neuronal ferroptosis. …”

Table_1_Bioinformatics Analysis Identifies Potential Ferroptosis Key Genes in the Pathogenesis of Intracerebral Hemorrhage.DOCX by Tongye Liu (10931763)

“…Treadmill training increased the expression of anti-inflammatory molecules TNFAIP3 and SLC2A1 and reduced the expression of MAPK1, ATF4, and MAPK8, indicating that treadmill training may be utilized as antioxidant therapy to decrease neuronal ferroptosis. …”

<b>Effects of obesity and hyperglycemia on postprandial insulin-mediated and non-insulin-mediated glucose disposal</b> by Bettina Mittendorfer (88840)

AMPK activators reduce DVL3 in cervical cancer cells. by H. T. Kwan (291038)

“…(C) Upon treatment with A23187 at different doses (0, 1.25 and 2.5 μM) for twenty hours, C33A and SiHa cells showed 80–90% reduction of DVL3 expression in a dose-dependent manner. …”

Supplementary Material for: Interdigitation and Ellipsoid Zones Disruption Correlate with Visual Outcomes among Treatment-Naive Patients with Diabetic Macular Edema by Sharef N. (10349900)

“…Patients underwent 3.9 ± 2.9 anti-VEGF injections for a mean of 9.1 ± 4.8 months. Following treatment, the mean Snellen visual acuity (VA) improved from 20/52 to 20/44 (<i>p</i> = 0.05), CMT decreased from 432.5 ± 141.4 μm to 375.2 ± 121.4 µm (<i>p</i> = 0.05) and IZ/EZ defect size decreased from 259.83 ± 375.94 µm to 65.34 ± 143.97 µm (<i>p</i> = 0.001). …”

Data_Sheet_1_Expression of the Neuroblastoma-Associated ALK-F1174L Activating Mutation During Embryogenesis Impairs the Differentiation of Neural Crest Progenitors in Sympathetic G... by Lucie Vivancos Stalin (6591539)

“…First, ALK-F1174L mediated an embryonic lethality at mid-gestation and an enlargement of SG with a disorganized architecture in Sox10-Cre;LSL-ALK-F1174L embryos at E10.5 and E11.5. …”

Oral Health Policy in Brazil: changes and ruptures during the period 2018-2021 by Lília Paula de Souza Santos (6146060)

“…Federal funding dropped in 2018 and 2019 (8.45%), followed by an increase in 2020 (59.53%) and decrease in 2021 (-5.18%). The study period was marked by economic and political crises aggravated by the COVID-19 pandemic. …”

Proton Transfer and Structure-Specific Fluorescence in Hydrogen Bond-Rich Protein Structures by Dorothea Pinotsi (1305144)

The effects of binge-pattern alcohol consumption on orthodontic tooth movement by Cristiano Miranda de Araujo (4643266)

“…Significance level was set at 5%.RESULTS: There was a decrease in the number of osteoclasts in EG at day 28. …”

Isocorydine Inhibits Cell Proliferation in Hepatocellular Carcinoma Cell Lines by Inducing G2/M Cell Cycle Arrest and Apoptosis by Hefen Sun (163541)

“…In addition, isocorydine treatment led to a decrease in the percentage of CD133⁺ PLC/PRF/5 cells. …”

Representative micro-CT images and bone mineral density (BMD). by Arianna B. Lovati (424733)

“…The image of group II shows a diffuse cortical and endosteal bone loss as signs of osteomyelitis; C) The histogram shows a high statistically significant difference in the BMD relative decrease of group II versus group III (unpaired t-test, ***P<0.0001; n = 5).…”

AD LCLs demonstrate differences in mitochondrial function as compared to control LCLs at baseline and after exposure to DMNQ. by Shannon Rose (506720)

“…(<b>C</b>) Maximal respiratory capacity was significantly elevated in the AD LCLs at 0 µM and 5 µM DMNQ compared to control LCLs, and the AD LCLs exhibited a greater decrease in maximal capacity as DMNQ increased as compared to control LCLs. …”

Knock-down of α2 and α3 integrin subunits by siRNA affects pancreatic cell adhesion to Netrin-4 and expression of islet-specific differentiation gene expression. by Mayra Yebra (346967)

“…Down-regulation of α2 and α3 integrin subunits in pancreatic cells resulted in a significant reduction of adhesion to Collagen IV (<b>B</b>) Laminin-5 (<b>C</b>), and to Netrin-4 (<b>D</b>), as well as a decrease in glucagon and/or insulin gene expression when cultured overnight on Netrin-4 (<b>E</b>). …”