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fold decrease » fold increase (Expand Search), fold increased (Expand Search)
wt decrease » we decrease (Expand Search), _ decrease (Expand Search), awd decreased (Expand Search)
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Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2‑Aminoquinoline Inhibitors
Published 2017“…We previously developed a class of membrane-permeable 2-aminoquinoline inhibitors and later rearranged the scaffold to decrease off-target binding. …”
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Bioavailable Soil Phosphorus Decreases with Increasing Elevation in a Subarctic Tundra Landscape
Published 2014“…Meadow soils did not have lower concentrations of Resin-P than heath soils, but they did have 2–fold and 1.5–fold higher concentrations of NaOH-extractable organic P and Residual P, respectively. …”
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Metabolites which were (A) reversibly decreased and (B) reversibly increased with smoking.
Published 2014“…<p>In panel A (top), differentially regulated metabolites were higher in air controls, decreased with smoking, and increased toward air control levels following smoking cessation. …”
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Clinical and genetic characteristics of 5 patients harboring mutations in the <i>NR5A1</i> gene.
Published 2014Subjects: -
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<i>Mertk</i><sup><i>-/-</i></sup> macrophages exhibit unpolarized distribution of filamentous actin and myosin II, and decreased FAK phosphorylation.
Published 2015“…Scale bars in (A) and (B), 5 μm. (C) Western blotting shows decreased FAK phosphorylation at tyrosine 397 after addition of apoptotic T cells for the indicated time points. …”
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Simultaneous ablation of Syt1 and Syt7 decreases the RRP size at inhibitory synapses: Rescue by WT but not mutant Syt1 or Syt7.
Published 2015“…Recordings were performed in the presence of 1 μM tetrodotoxin, 20 μM CNQX, and 50 μM AP5 to isolate inhibitory currents. <b>B.</b> Simultaneous ablation of Syt1 and Syt7 decreases the RRP size of inhibitory synapses in a manner that is rescued by WT Syt7 (Syt1<sup>WT</sup>) but not Syt7 with mutations in the top C2 domain sequences containing the Syt7 Ca<sup>2+</sup> binding sites (Syt7<sup>C2A</sup>*<sup>B</sup>*). …”
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(R)-albuterol decreases cytokine mRNA levels in activated T cells
Published 2011“…</p><p></p> (R)-albuterol, (S)-albuterol or racemic albuterol (R + S) at a dose (10M) were added to T (EL-4) cells pre-activated with mitogens Concanavalin A (Con A, 5 μg/ml) and phorbol myristate acetate (PMA, 100 ng/ml) (CP). …”
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Flow chart of the study procedures.
Published 2023“…</p><p>Conclusions</p><p>In a mostly HIV patient population, RPR titer can show more than four-fold spontaneous increase or decrease within 1–3 months. …”
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