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Decrease of SMAD3 protein, but not SMAD2 in DBA iPSCs.
Published 2015“…The ratio of protein level to WT is labelled under the image. A) No change of mRNA level of <i>SMAD2</i> or <i>SMAD3</i> in the DBA iPSCs with <i>RPS19</i> or <i>RPL5</i> mutations. …”
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SLE T cells display more genes with increased rather than decreased expression.
Published 2015“…<p><b>A)</b> Distribution of expression stratified at the 1.5-, 2-fold and q<0.05 CUFFDIFF2 significance levels. …”
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Decreased Brain Levels of Vitamin B12 in Aging, Autism and Schizophrenia
Published 2016“…Vitamin B<sub>12</sub> (cobalamin, Cbl) exists in multiple forms, including methylcobalamin (MeCbl) and adenosylcobalamin (AdoCbl), serving as cofactors for MS and methylmalonylCoA mutase, respectively. We measured levels of five Cbl species in postmortem human frontal cortex of 43 control subjects, from 19 weeks of fetal development through 80 years of age, and 12 autistic and 9 schizophrenic subjects. …”
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MMR mutants show decreased mating-type silencing.
Published 2020“…The plasmids (<i>pRS425</i> and <i>pRS425-Gal10-MSH2</i>) were transformed to <i>msh2</i>Δ mutants in both WT (<i>his3Δ</i>) and UCC3505 backgrounds. Cells were five-fold serially diluted and then spotted onto SD-ura-leu + 2% glucose (left) or SD-ura-leu + 2% galactose (right) agar plates. …”
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Molecular and Structural Analysis of Mosaic Variants of Penicillin-Binding Protein 2 Conferring Decreased Susceptibility to Expanded-Spectrum Cephalosporins in <i>Neisseria gonorrh...
Published 2010“…Agents Chemother. 50</i>, 3638−3645]. However, we observed that the minimum inhibitory concentrations (MICs) of penicillin, ceftriaxone, and cefixime for a wild-type strain (FA19) containing a <i>penA</i> gene with these three mutations increased only 1.5-, 1.5-, and 3.5-fold, respectively. …”
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Bioavailable Soil Phosphorus Decreases with Increasing Elevation in a Subarctic Tundra Landscape
Published 2014“…Meadow soils did not have lower concentrations of Resin-P than heath soils, but they did have 2–fold and 1.5–fold higher concentrations of NaOH-extractable organic P and Residual P, respectively. …”
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The rate of lariat formation is decreased two-fold by isoginkgetin treatment.
Published 2014“…<p>(<b>A</b>) Genome-wide expression of 5′ splice sites, 3′ splice sites, and introns are increased relative to exons upon treatment of HeLa cells with isoginkgetin (30 µM, 18 hours), based on total RNA-Seq (dUTP method <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0089673#pone.0089673-Parkhomchuk1" target="_blank">[18]</a>, Illumina). …”
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