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DataSheet_1_Specific Targeting of Lymphoma Cells Using Semisynthetic Anti-Idiotype Shark Antibodies.pdf
Published 2020“…First initial experiments to utilize the generated vNAR-Fc variants for BCR-clustering to induce apoptosis or ADCC/ADCP did not result in a significant decrease of cell viability. …”
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20012
Fluctuations in airway bacterial communities associated with clinical states and disease stages in cystic fibrosis
Published 2018“…We sequenced the V3-V5 hypervariable region of the bacterial 16S rRNA gene in DNA derived from 631 sputum specimens collected from 111 CF patients over 10 years. …”
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20013
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Equilibrium unfolding studies of refolded hVDAC-2 using GdnHCl.
Published 2014“…The color scheme used in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0092183#pone-0092183-g005" target="_blank">Figure 5</a> for the various samples is also retained here. …”
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5-FU nanoparticle enhanced 5-FU to inhibit the growth of hepatic caner through ASGPR -mediated endocytosis <i>in vitro</i>.
Published 2013“…At the 24, 48 and 72 h time points, the rate of tumor inhibition rate decreased from in the order GC/5-FU-SMMC-7721 to 5-FU-SW480 to 5-FU-SMMC-7721 to CS/5-FU-SMMC-7721 to CS/5-FU-SW480 to GC/5-FU-SW480.…”
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20018
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20020
Image_4_Substrate Specificity of Acyltransferase Domains for Efficient Transfer of Acyl Groups.TIF
Published 2018“…In Streptomycestsukubaensis YN06, we found that AT4<sub>FkbB</sub> [an AT in the fourth module of tacrolimus (FK506) PKS] transferred both allylmalonyl (allmal) and emthylmalonyl (ethmal) units to ACPs, which was supposed responsible for the production of both FK506 and its analog FK520, respectively. Mutations of five residues in AT4<sub>FkbB</sub> (Q119A, L185I-V186D-V187T, and F203L) caused decreased efficiency of allmal transfer, but a higher ratio of ethmal transfer, supposedly due to less nucleophilic attacks between Ser599 in the active site of AT4<sub>FkbB</sub> and the carbonyl carbon in the allmal unit, as observed from molecular dynamics simulations. …”