The interaction between Dvl1 and Eps8 is required for Wnt3a-mediated axonal remodeling. by Eleanna Stamatakou (781280)

“…(B) Expression of the PDZ domain of Dvl1 in N2a cells decreases the binding of Dvl1 and Eps8 by 38%, as assessed by co-immunoprecipitation experiments. …”

Comparing Cosine and Sine Functions for Calculating the Magnetic Shielding of ²⁹Si Nuclei across Siliceous Zeolites by A. A. Rybakov (4812234)

“…The models, along with α-quartz, were considered to evaluate the advantages of the effects on both chemical shifts and chemical shift anisotropies, as measured for α-quartz and ZSM-12. The decrease of the O dipole with the Si–O–Si angle is usually interpreted as a variation of the electronic density at the O lone pairs. …”

Stem Cell-Derived, microRNA-Carrying Extracellular Vesicles: A Novel Approach to Interfering with Mesangial Cell Collagen Production in a Hyperglycaemic Setting by Sara Gallo (3111309)

“…This resulted in STAT5 down-regulation and a decrease in miR-21 content, TGFβ expression and matrix protein synthesis within MCs. …”

Noise pollution limits metal bioaccumulation and growth rate in a filter feeder, the Pacific oyster <i>Magallana gigas</i> by Mohcine Charifi (4535101)

“…This latter conclusion points towards a potential risk in terms of ecosystem productivity.…”

Silencing or suppression of TRPM7 impairs ERK and JNK signaling pathways. by Zhao Zeng (478844)

“…Densitometric analysis shows a decrease of p-ERK and p-JNK. TRPM7 siRNA significantly decreases the protein level of TRPM7 by 36.5% (n = 3), the phosphorylation of ERK and JNK by 67.8% ± 22.4% (n = 3) and 80.5% ± 25.3% (n = 3) respectively (*, <i>p</i> < 0.05). …”

Impaired differentiation of alveolar epithelial type I cells in E18.5 <i>Snx5^-/-</i> lungs. by Sun-Kyoung Im (36750)

“…T1α, a marker of alveolar epithelial type I cells, was significantly decreased in <i>Snx5^-/-</i> compared to <i>Snx5^+/+</i> lung (n  =  5). …”

Cucurbitacin E Chemosensitizes Colorectal Cancer Cells via Mitigating TFAP4/Wnt/β-Catenin Signaling by Peng Yang (296696)

“…Remarkably, the combination of CE and 5-FU treatment attenuated β-catenin, MDR1, and ABCC1 expressions, while TFAP4 overexpression reversed their expressions by 2.68 ± 0.46-, 0.72 ± 0.44-, and 0.93 ± 0.21-fold, respectively. …”

Overview of differences in modelling approach and data used by the UN IGME and the IHME for estimating the U5MR and the number of under-five deaths. by Leontine Alkema (111799)

“…In only four countries did this ratio change significantly over time, and in all cases it was decreasing, not increasing. Based on this analysis, it was decided to apply a 10% upward adjustment to under-five mortality for Belarus, Hungary, and Lithuania, and a 20% adjustment for the other countries, including the Russian Federation. …”

Image_5_miR-181b-5p May Regulate Muscle Growth in Tilapia by Targeting Myostatin b.JPEG by Zaoya Zhao (8071304)

“…</p><p>Conclusion: Taken together, our results suggested that miR-181b-5p could promote the growth of skeletal muscle by decreasing the MSTNb protein level in tilapia.…”

Table5_Tau protein modulates an epigenetic mechanism of cellular senescence in human SH-SY5Y neuroblastoma cells.docx by Claudia Magrin (13969128)

Image1_Pan-cancer analysis of the prognostic and immunological roles of DEAD-box helicase 5 (DDX5) in human tumors.TIF by Shixuan Liu (11269115)

“…The aberrant regulation of DDX5 expression possibly plays a significant role in the genesis of cancer. …”

FIG1A- FIG1N. by Elaine Carvalho de Oliveira (11630455)

Average velocity per 5% of the distance during normal and 3, 4, and 5 kg assisted 60 m sprints for men and women. by Roland van den Tillaar (6407390)

Malaria prevalence over the years is presented by age (Fig 3A), sex (Fig 3B), history of fever (Fig 3C), geographical zones (Fig 3D), ITN use (Fig 3E), and elevation (Fig 3F). by Frank Chacky (3446654)

<em>Saccharomyces boulardii</em> Improves Intestinal Epithelial Cell Restitution by Inhibiting αvβ5 Integrin Activation State by Alexandra Canonici (133661)

“…Indeed, by using cell adhesion assays, we showed that <em>Sb</em> supernatant contains heat sensitive molecule(s), with a molecular weight higher than 9 kDa, which decreased αvβ5 integrin-mediated adhesion to vitronectin by competing with the integrin. …”

All-Atom Simulations Reveal the Effect of Membrane Composition on the Signaling of the NKG2A/CD94/HLA‑E Immune Receptor Complex by Martin Ljubič (15680161)

“…Our results reveal significant variations in the behavior of the immune complex structure across five different membrane compositions, which include POPC, POPA, DPPC, and DLPC phospholipids, and a mixed POPC/cholesterol system. …”

Table_1_Development of multiplex real-time PCR for simultaneous detection of SARS-CoV-2, CCoV, and FIPV.pdf by Yan Liu (25061)

“…</p>Methods and results<p>In this study, we developed a novel multiplex TaqMan-probe-based real-time PCR assay for the simultaneous detection and differentiation of SARS-CoV-2, CCoV, and FIPV. …”

TRPM7 regulates intracellular Ca²⁺ and Mg²⁺ concentration of cortical astrocytes. by Zhao Zeng (478844)

“…However, knockdown of TRPM7 in mouse cortical astrocytes significantly decreases intracellular Mg²⁺ by 43.5% ± 9.8% (*, <i>p</i> < 0.05, n = 4). …”

Data Sheet 5_Regulatory mechanism of ABCB1 transcriptional repression by HDAC5 in rat hepatocytes under hypoxic environment.zip by Ziqin Wei (19433134)

“…In the BRL hypoxia model, ABCB1 and SP1 expression decreased while HDAC5 expression increased. After SAHA treatment, ABCB1 and SP1 expression were upregulated while HDAC5 was downregulated. …”

Silencing TRPM7 in Mouse Cortical Astrocytes Impairs Cell Proliferation and Migration via ERK and JNK Signaling Pathways by Zhao Zeng (478844)

“…Knocking down TRPM7 with specific siRNA impairs the proliferation and migration of astrocytes by 40.2% ± 3.9% and 40.1% ± 11.5%, respectively. Consistently, inhibition of TRPM7 with 2-aminoethoxydiphenyl borate (2-APB) also decreases astrocyte proliferation and migration by 46.1% ± 2.5% and 64.2% ± 2.4%. …”