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40221
Conflicting selection pressures prevent the outgrowth of TIP-resistant HIV mutants in a host population.
Published 2016“…For example, at <i>P</i> = 2.5, decreasing <i>η</i> results in major increases in transmission from TIP<sup>+</sup> individuals (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004799#pcbi.1004799.g001" target="_blank">Fig 1B</a>) that overwhelm the modest decreases in transmission from TIP<sup>-</sup> individuals, essentially removing the evolutionary conflict at the population-scale. …”
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40222
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40223
E4orf4 sensitizes cells to killing by drugs inducing DNA damage or replication stress.
Published 2016“…Cell survival was measured by a clonogenic assay using various cell dilutions, without further Dox addition. …”
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40224
Patient recruitment diagram.
Published 2023“…</p><p>Results</p><p>There was a reported decrease in mobility from admission to discharge in both men (p = 0.02) and women (p = 0.01). …”
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40225
Protein expression of HO-1, HO-2 and Nrf2 in the gastric mucosa of intact rats and in those exposed to 75% ethanol with or without the pretreatment with CORM-2 applied i.g. in thre...
Published 2015“…Panels A and C: pretreatment with CORM-2 (100 mg/kg i.g.) significantly decreased the signal of HO-1 (A) and Nrf2 (C) expression as compared to those recorded in vehicle-control gastric mucosa (p<0.05) as marked by cross. …”
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40226
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40227
Negative Epistasis between Sickle and Foetal Haemoglobin Suggests a Reduction in Protection against Malaria
Published 2015“…An increase in HbF was associated with a decrease in risk of malaria OR=0.50 (95%CI: 0.28, 0.90; p=0.021) in HbAA, whereas for HbSS the risk of malaria increased OR=2.94 (1.44, 5.98; p=0.003). …”
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40228
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40229
Enhanced pyruvate dehydrogenase activity improves cardiac outcomes in a murine model of cardiac arrest
Published 2017“…In both heart and brain, CA increased lactate concentrations (1.9-fold and 3.1-fold increase, respectively, <i>P</i><0.01), decreased PDH enzyme activity (24% and 50% reduction, respectively, <i>P</i><0.01), and increased PDK protein expressions (1.2-fold and 1.9-fold, respectively, <i>P</i><0.01). …”
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40230
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40231
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40232
Effects of cardiopulmonary bypass on NOP (A) and ppNOC (B) mRNA, N/OFQ peptide (C) concentrations.
Published 2013“…For ppNOC PCR 6 samples at t=0, 4 samples at t=3h and 6 samples at t=24 failed to amplify and there was insufficient material for analysis of a further 2 samples at t=24. Plasma N/OFQ measurements were made in samples from all patients at all time points (n=120), but for 5 samples at t=0, 4 samples at t=3h and 3 samples at t=24h, measurements were set at the lower limit of detection (1.25pg mL<sup>-1</sup>). …”
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40233
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40234
Uptake of FITC-labeled dextran by XS52 cells via macropinocytosis in a PI3K dependent manner.
Published 2013“…Values of the densitometric analysis are expressed as x-fold decrease of phosphorylated Akt (p-Akt) formation compared to untreated cells ± SEM from three experiments. …”
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40235
PrA inhibited DC maturation responding to LPS and diminished DC-mediated T cell allostimulation.
Published 2013“…The highest dose induced a significant decrease in viable DC count, so only 5 nM and 20 nM were used in subsequent experiments. …”
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40236
Depth-temperature profile for Shark 33 demonstrating a shift in vertical movement pattern.
Published 2015“…<p>The reverse diel vertical migration transitions with a progressive decrease in daytime surface time and increase in vertical oscillations forming V-shaped profiles that span both day and night.…”
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40237
Adverse event list.
Published 2025“…</p><p>Non-motor symptoms of PD, motor parkinsonian signs off medication, and quality of life improved significantly during the treatment phase, including the MDS-UPDRS total score (mean decrease −11.09; 95% Confidence Interval [CI]; −18, −4.1; <i>p</i> = 0.006), the Parkinson’s disease Questionnaire-39 (PDQ-39) summary index (mean decrease −2.91; 95% CI; −4.4, −1.4; <i>p</i> = 0.005), and the Non-Motor Symptoms Questionnaire (NMS-Quest) (mean decrease −4.27; 95% CI; −6.5, −2.1; <i>p</i> = 0.009). …”
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40238
Patient characteristics.
Published 2025“…</p><p>Non-motor symptoms of PD, motor parkinsonian signs off medication, and quality of life improved significantly during the treatment phase, including the MDS-UPDRS total score (mean decrease −11.09; 95% Confidence Interval [CI]; −18, −4.1; <i>p</i> = 0.006), the Parkinson’s disease Questionnaire-39 (PDQ-39) summary index (mean decrease −2.91; 95% CI; −4.4, −1.4; <i>p</i> = 0.005), and the Non-Motor Symptoms Questionnaire (NMS-Quest) (mean decrease −4.27; 95% CI; −6.5, −2.1; <i>p</i> = 0.009). …”
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40239
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40240
Socket Shield Technique to Improve the Outcomes of Immediate Implant: A Systematic Review and Meta-Analysis
Published 2023“…Additionally, SST had a significant increase in implant stability (MD = 3.46, 95 % CI [1.22, 5.69], p = 0.002) and pink esthetic score (MD = 1.60, 95% CI [0.90, 2.30], p < 0.0001). …”
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