miR-1247-3p was downregulated in CRC resistant cells. by Dequan Wang (6007007)

Downregulation of miR-1247-3p inhibited apoptosis and reduced chemosensitivity in cells. by Dequan Wang (6007007)

Loewe synergy-antagonism score analysis shows additive and synergistic effects after ALKi and ABT-199 combination treatment. by Richard Junior Zapata Dongo (17912565)

miR-1247-3p was downregulated in tissues of patients with CRC and was associated with prognosis and drug resistance. by Dequan Wang (6007007)

Requirement of D2R–RGS balance under various levels of [<i>DA</i>]_basal and [<i>DA</i>]_dip. by Hidetoshi Urakubo (578508)

Overexpression of miR-1247-3p promoted apoptosis and inhibited resistance in drug-resistant cells. by Dequan Wang (6007007)

Differential NKG2D expression on CD56+CD3+ lymphocytes from chronic genotype 1 infection is associated with core protein aa substitutions. by Po-sung Chu (549427)

Effect of <i>attP40</i> and derivatives on <i>msp-300</i> transcript levels. by Kevin van der Graaf (14259532)

Parameter values for patches in the simulated landscape. by Miguel A. Acevedo (381283)

Effect of Methanol Additives on Soot Inhibition during <i>n</i>‑Decane Pyrolysis by Lu Liu (171341)

“…The simulation results show that the mole fractions of C₂H₂, C₃H₃, C₅H₅, and BINs decrease significantly with methanol addition. …”

Effect of Methanol Additives on Soot Inhibition during <i>n</i>‑Decane Pyrolysis by Lu Liu (171341)

“…The simulation results show that the mole fractions of C₂H₂, C₃H₃, C₅H₅, and BINs decrease significantly with methanol addition. …”

Functional validation of a miRNA-34a-TREM2–3’UTR interaction. by Surjyadipta Bhattacharjee (3181674)

“…<p><b>(A)</b> ribonucleotide sequence of the 299 nt TREM2-mRNA-3’-UTR is shown in the 5’-3’ direction; the 22 nt miRNA-34a-TREM2 3’UTR complementarity-interaction region is indicated by a black underline and the 8 nt TREM2-mRNA-3’-UTR seed sequence <b>5’-ACACUGCU-3’</b> is overlaid in yellow; a single arrowhead indicates the 5’ end of a poly A+ tail in the TREM2 mRNA (22 ‘A’ nt shown; the length of this poly A+ tail is variable); TREM2 mRNA sequence derived from NM_018965; TREM2 transcript is the major X1 variant (see also <a href="http://switchdb.switchgeargenomics.com/productinfo/id_801321/" target="_blank">http://switchdb.switchgeargenomics.com/productinfo/id_801321/</a>) (<b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.g003" target="_blank">Fig 3</a></b>); <b>(B)</b> TREM2-mRNA-3’UTR expression vector luciferase reporter assay (pLightSwitch-3’UTR; Cat#S801178; Switchgear Genomics, Palo Alto CA); in this vector, the entire 299 nucleotide TREM2 3’UTR was ligated into the unique Nhe1-Xho1 site; <b>(C)</b> control C8B4 murine microglial cells, 1 week in culture; phase contrast bright field microscopy 20x; C8B4 cells transfected with the TREM2-mRNA-3’UTR expression vector luciferase reporter were treated exogenously with miRNA-34a, a scrambled control miRNA-34a (miRNA-sc) or control miRNA-183; see references and text for further details [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.ref018" target="_blank">18</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.ref019" target="_blank">19</a>]; <b>(D)</b> compared to control, C8B4 cells transfected with a scrambled (<b>sc</b>) control pLightSwitch-3’UTR vector, the TREM2-mRNA-3‘UTR vector exhibited decreased luciferase signal to a mean of 0.16-fold of controls in the presence of miRNA-34a; this same vector exhibited no change in the presence of the control miRNA-34a-sc or miRNA-183; for each experiment (using different batches of MG cells) a control luciferase signal was generated and included separate appropriate controls with each analysis; in addition a control vector β-actin-3’UTR showed no significant effects on the relative luciferase signal yield after treatment with either miRNA-183 or miRNA-34a (data not shown); dashed horizontal line set to 1.0 for ease of comparison; N = 5; *<i>p</i><0.001 (ANOVA). …”

Table_5_Evidence of exhausted lymphocytes after the third anti-SARS-CoV-2 vaccine dose in cancer patients.docx by Javier David Benitez Fuentes (14281331)

“…The patients with decreased cellular response after the booster had a higher expression of PD1⁺CD8⁺ and CD57⁺PD1⁺CD8⁺ exhausted T cells compared with those with an increased cellular response both in vivo and in vitro. …”

Recombinant soluble HLA-DO expression and characterization. by Yuri O. Poluektov (443384)

“…(B) Soluble co-expressed DO/DM complex was purified using Mags.DO5 monoclonal antibody affinity column. Four replicate samples were resolved on Bis-Tris SDS-PAGE gels in decreasing protein concentrations. …”

Histology of hearts and pancreas of Swiss mice at day 10 after oral inoculation with CVB3 wild type and mutant viruses as described previously [26]. by Jawhar Gharbi (11492361)

Frailty and quality of life among older people with and without a cancer diagnosis: Findings from TOPICS-MDS by Noralie Geessink (4688338)

“…A ten percent increase in frailty was also associated with a decrease in QOL at baseline (CSAL:-0.35 (95%-CI:-0.38;-0.32), EQ-5D:-0.12 (95%-CI:-0.12;-0.11)) and follow-up (CSAL:-0.27 (95%-CI:-0.30;-0.24), EQ-5D:-0.07 (95%-CI:-0.07;-0.06)). …”

Figure S1 - Antimicrobial Resistance in Invasive Non-typhoid <em>Salmonella</em> from the Democratic Republic of the Congo: Emergence of Decreased Fluoroquinolone Susceptibility an... by Octavie Lunguya (122719)

Effects of HWHF on insulin secretion from (A & B) BRIN-BD11 cells and (C) pancreatic islets, (D) protein glycation, (E) insulin release in the presence of established stimulators o... by Prawej Ansari (12191266)

Hypothetical examples of the wisdom of crowds by a majority rule. by Masaru Shirasuna (14755745)

Fluoxetine ameliorates cartilage degradation in osteoarthritis by inhibiting Wnt/β-catenin signaling by Kentaro Miyamoto (123271)

“…Fluoxetine inhibited both Wnt3A- and LiCl-induced loss of proteoglycans in chondrogenically differentiated ATDC5 cells. …”