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A decrease in cellular RNA increases the insolubility of TDP-43.
Published 2013“…(C) Immunoblots of the immunoprecipitated protein with anti-V5 antibody or control IgG. (D) Reverse transcription-PCR (RT-PCR) of hNFL from immunoprecipitated RNA. …”
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Flow chart of the study procedures.
Published 2023“…</p><p>Conclusions</p><p>In a mostly HIV patient population, RPR titer can show more than four-fold spontaneous increase or decrease within 1–3 months. …”
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MiR-129-5p levels were decreased in mouse depression models.
Published 2025“…<p><b>A.</b> Experimental schedule. All mice underwent behavioral tests following CRS treatment. …”
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TGFβ1 expression was increased, and RASAL1 expression was decreased in NTM cells in response to a hypoxic environment.
Published 2016“…A 0hr Control was set to 100%, and the normoxic and hypoxic results were presented as a percentage of this; Normoxic = 95.5%, Hypoxic = 159.4% (P<0.01). n = 3 *P<0.05, **P<0.01. …”
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Relationship between Differential Hepatic microRNA Expression and Decreased Hepatic Cytochrome P450 3A Activity in Cirrhosis
Published 2013“…In this study, we examined if certain microRNAs (miRNA) are associated with decreased hepatic CYP3A activity in cirrhosis.…”
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Missense Variant in MAPK Inactivator <i>PTPN5</i> Is Associated with Decreased Severity of Post-Burn Hypertrophic Scarring
Published 2016“…</p><p>Conclusions</p><p>We report <i>PTPN5</i> as a novel genetic locus associated with HTS severity. …”
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Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2‑Aminoquinoline Inhibitors
Published 2017“…We previously developed a class of membrane-permeable 2-aminoquinoline inhibitors and later rearranged the scaffold to decrease off-target binding. …”
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