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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
منشور في 2024"…Mutation of the two residues in NLuc revealed a decreased but stable activity of the R162A, but not Q32A, mutant NLuc in live cell and in vitro assays performed using lysates prepared from cells expressing the proteins and with the furimazine substrate. …"
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apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes
منشور في 2021"…</p><h3>Conclusions</h3><p dir="ltr">Apoproteins apoA2, apoC1, apoC3 and apoE are decreased in women with GDM and may have a role in inflammation, as apoA2 and C3 correlated with CRP. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…"
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…We identified γ-secretase inhibitor (LY411575) as a potent regulator of osteoblastic differentiation of hBMSC that may be useful as a therapeutic option for treating conditions associated with ectopic bone formation.…"
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Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex
منشور في 2022"…<p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences <a href="https://dx.doi.org/10.3389/fmolb.2022.846996" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.846996</a>, published online 22 July 2022.…"
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
منشور في 2023"…Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …"
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
منشور في 2023"…Among VN individuals, anti-S1 IgA levels began to decrease significantly (1.4-fold; p = 0.007) after two months, and both NtAb and S-RBD IgG levels began to decline significantly (NtAb: 2.0-fold; p = 0.042, S-RBD IgG: 2.4-fold; p = 0.035) after three months. …"
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neurons
منشور في 2019"…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …"
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Deep Reinforcement Learning Powered IRS-Assisted Downlink NOMA
منشور في 2022"…As the imperfection increases by ten times, the rate decreases by more than 10%.</p><h2>Other Information</h2><p dir="ltr">Published in: IEEE Open Journal of the Communications Society<br>License: <a href="https://creativecommons.org/licenses/by/4.0/legalcode" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1109/ojcoms.2022.3165590" target="_blank">https://dx.doi.org/10.1109/ojcoms.2022.3165590</a></p>…"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…In aged HSA-mUCP1 mice, urinary MG-derived AGEs/FL ratio was decreased ca. 60% whereas there was no change in CML/FL ratio – a marker of oxidative damage. …"
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Insights Into SARS-CoV-2 S1-RBD-ACE2 Interaction Using Computational Tools and Membrane Microarray Platform
منشور في 2024"…Further, treatment of cells with pitstop2, but not blebbistatin, resulted in a decrease in the S1-RBD depletion. …"
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Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis
منشور في 2019"…<h3>Background</h3><p dir="ltr">Brief intervention is a critical method for identifying patients with problematic substance use in primary care settings and for motivating them to consider treatment options. …"
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Effect of speed and gradient on plantar force when running on an AlterG® treadmill
منشور في 2021"…Gradient made little difference except for a downhill grade of − 5% decreasing force peaks as compared to level or uphill running.…"
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Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications
منشور في 2019"…In the TCGA TNBC/Basal-like cohort the <b><i>MAP3K21</i></b><b> </b><b>rs1294255-G</b> allele was associated with a decreased OVS. …"
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Investigating the Role of FOXA2 Transcription Factor in Adipogenesis Using Human-Induced Pluripotent Stem Cells
منشور في 2025"…However, the role of FOXA2 in human adipocytes has not been studied. Therefore, in this study, we aimed to investigate the role of <i>FOXA2</i> in adipogenesis using previously established wild-type induced pluripotent stem cells (WT-iPSCs) and <i>FOXA2</i> knockout iPSCs (FOXA2 KO iPSCs). …"
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Enhanced thermoelectric properties of Bi<sub>2</sub>Te<sub>2.55</sub>Se<sub>0.45</sub> nanocomposites using eco-friendly Eocene Midra Shale palygorskite nanofillers: A sustainable...
منشور في 2025"…The EMS was obtained from one of Qatar’s substantial hydrocarbon reservoirs and mixed with the Bi2Te2.55Se0.45 alloy using ball-milling and hot-pressing techniques. …"
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The impact of COVID‐19 pandemic lockdown on smoking habits and lifestyle: A cross‐sectional study
منشور في 2023"…While those who had a decrease in their smoking level experienced a somehow healthier lifestyle regarding nutrition and other aspects.…"